Due to the high decay rate of the non-radiative transition of long wavelengths, the molecular design of efficient and stable near-infrared(NIR) electroluminescent materials remains a big challenge. Herein,a new tetrad...Due to the high decay rate of the non-radiative transition of long wavelengths, the molecular design of efficient and stable near-infrared(NIR) electroluminescent materials remains a big challenge. Herein,a new tetradentate cyclometalated platinum(II) complex with an N∧C∧C∧N coordinated framework has been developed and used as a dopant for NIR organic light-emitting diodes(OLEDs). The complex exhibited a short-lived(0.5–1.5 μs) metal-to-ligand charge transfer(MLCT) excited state in doped and neat films. The resulting NIR OLEDs(λ_(EL)= 730 nm) achieved maximum external quantum efficiency(EQE_(max))of 5.2% and radiance of 74626 m W sr^(-1)m^(–2). Of note, the device exhibited excellent stability with operational lifetime of 119 h for LT_(90). This work demonstrated the great potential of tetradentate platinum(II)complexes in the field of NIR OLEDs.展开更多
Flooding is an abiotic stress that impacts soybean [Glycine max (L.) Merr.] growth and reduces seed germination. Effect of flooding on soybean plant grown at different growth stage has been previously conducted and re...Flooding is an abiotic stress that impacts soybean [Glycine max (L.) Merr.] growth and reduces seed germination. Effect of flooding on soybean plant grown at different growth stage has been previously conducted and reported. However, soybean seed germination responses to flood stress are largely unknown. The objective of this study was to elucidate flooding influence on soybean seed germination after planting in the field. The research showed that seed germination rate (SGR) of each genotype, without flood stress, was significantly different and ranged between 64.7% to 84.0% and 69.0% to 90.7% while using untreated and fungicide-treated seed (P < 0.0001), respectively. Results indicated that fungicide treatment improved soybean seed survival and germination in the field. The average of SGR of high-yielding soybean group was significantly higher than those of non-high-yielding soybean (P < 0.0001). The results indicated that high-yielding trait of each genotype was correlated with seed germination and survival. Under flood stress in the field, SGR means of untreated and fungicide-treated seed significantly decreased over eight flooding treatment times (P Flooding effect on germination between untreated and fungicide-treated seed was not significantly different (P = 0.1559). Furthermore, comparing the high-yielding and flood-tolerant soybean groups showed no difference in their SGR means over eight flooding treatment times (P = 0.7687 and P = 0.8490), indicating that soybean seed germination did not depend on genotype, yield, and flood tolerance trait, and seed treated by fungicide did not increase its germination in the field under the flood stress. Hence, it is necessary to develop new soybean seed pelleting to improve seed germination in the field under flooding conditions.展开更多
This study examines the impact of the Belt and Road Initiative(BRI)on China's export potential at the product level.Using country–product-level data from the Centre d'Etudes Prospectives d'Informations In...This study examines the impact of the Belt and Road Initiative(BRI)on China's export potential at the product level.Using country–product-level data from the Centre d'Etudes Prospectives d'Informations Internationales-Base pour l'Analyse du Commerce International(CEPII-BACI),which includes 5,049 product types across 196 economies from 2007 to 2022,it explores the trade effects of the BRI and its mechanisms from the perspective of global value chains.The results indicate that the BRI has increased China's product export potential significantly to participating countires.The BRI has had the greatest impact on capital goods and labor-and capital-intensive industries.The effect has been most pronounced in China's exports to Southeast Asia,South Asia,and Europe.The mechanism analysis reveals that the BRI has improved the division of labor in the global value chains for participating countries along the BRI,strengthened China's position in their output supply chains,and stimulated the growth of China's exports.展开更多
Human adenoviruses(HAdvs)are major respiratory pathogens.Specifically,human adenovirus type 4(HAdV4)and human adenovirus type 7(HAdV7)are known for causing fever and pneumonia,with docu-mented cases of fatalities amon...Human adenoviruses(HAdvs)are major respiratory pathogens.Specifically,human adenovirus type 4(HAdV4)and human adenovirus type 7(HAdV7)are known for causing fever and pneumonia,with docu-mented cases of fatalities among the population.In recent years,HAdV4/HAdv7 has been implicated in caus-ing substantial outbreaks,leading to increased morbidity in multiple countries.Most HAdV4 and HAdV7 infections have been reported in North America,Asia,Europe,Africa,South America,Oceania,and the Middle East.Most fatalities occurred in North America(the United States)and Asia(China and Singapore).Engineered recombinant adenoviruses have played a crucial role as vaccine vectors.In this study,we con-structed a recombinant adenovirus,Ad4ITRmut-Ad7E3,and evaluated it in vitro and in vivo.We observed that the replication rate of Ad4ITRmut-Ad7E3 was lower than that of the RI-67 strain,indicating that the mutation of inverted terminal repeats(ITRs)weakened the replication ability of HAdV4.Immunization of BALB/c mice with the bivalent Ad4ITRmut-Ad7E3 vaccine strain,administered by intraperitoneal injection and oral gavage,resulted in the elicitation of neutralizing antibodies targeting HAdV4 and HAdv7.This finding not only pro-vides a novel method and technique for the efficient construction of a polyvalent recombinant adenovirus vac-cine candidate against HAdV4 and HAdv7 but also against other prevalent adenovirus serotypes such as HAdV3,HAdV11,HAdV14,and HAdv55,from various regions.展开更多
Fracture is one of the most common traumatic diseases in clinical practice,and metal plates have always been the first choice for fracture treatment because of their high strength.However,the bone plates have high ela...Fracture is one of the most common traumatic diseases in clinical practice,and metal plates have always been the first choice for fracture treatment because of their high strength.However,the bone plates have high elastic modulus and do not match the biomechanics of human bone,which adversely affects callus formation and fracture healing.Moreover,the complex microenvironment in the human body can induce corrosion of metallic materials and release toxic ions,which reduces the biocompatibility of the bone plate,and may necessitate surgical removal of the implant.In this study,tantalum(Ta)was deposited on porous silicon carbide(SiC)scaffolds by chemical vapor deposition technology to prepare a novel porous tantalum(pTa)trabecular bone metal plate.The function of the novel bone plate was evaluated by implantation in an animal fracture model.The results showed that the novel bone plate was effective in fracture fixation,without breakage.Both X-ray and microcomputed tomography analysis showed indirect healing by both pTa trabecular bone metal plates and titanium(Ti)plates;however,elastic fixation and obvious callus formation were observed after fixation with pTa trabecular bone metal plates,indicating better bone repair.Histology showed that pTa promoted the formation of new bone and integrated well with the host bone.Therefore,this novel pTa trabecular bone metal plate has good prospects for application in treating fractures.展开更多
基金financially supported by the National Natural Science Foundation of China (Nos. 51903157 and 52130308)the Shenzhen Science and Technology Program (Nos. KQTD20170330110107046 and ZDSYS20210623091813040)the School of Materials Science and Engineering, Jiangsu Engineering Laboratory of Light-Electricity-Heat Energy-Converting Materials and Applications (No. GDRGCS2021001)。
文摘Due to the high decay rate of the non-radiative transition of long wavelengths, the molecular design of efficient and stable near-infrared(NIR) electroluminescent materials remains a big challenge. Herein,a new tetradentate cyclometalated platinum(II) complex with an N∧C∧C∧N coordinated framework has been developed and used as a dopant for NIR organic light-emitting diodes(OLEDs). The complex exhibited a short-lived(0.5–1.5 μs) metal-to-ligand charge transfer(MLCT) excited state in doped and neat films. The resulting NIR OLEDs(λ_(EL)= 730 nm) achieved maximum external quantum efficiency(EQE_(max))of 5.2% and radiance of 74626 m W sr^(-1)m^(–2). Of note, the device exhibited excellent stability with operational lifetime of 119 h for LT_(90). This work demonstrated the great potential of tetradentate platinum(II)complexes in the field of NIR OLEDs.
文摘Flooding is an abiotic stress that impacts soybean [Glycine max (L.) Merr.] growth and reduces seed germination. Effect of flooding on soybean plant grown at different growth stage has been previously conducted and reported. However, soybean seed germination responses to flood stress are largely unknown. The objective of this study was to elucidate flooding influence on soybean seed germination after planting in the field. The research showed that seed germination rate (SGR) of each genotype, without flood stress, was significantly different and ranged between 64.7% to 84.0% and 69.0% to 90.7% while using untreated and fungicide-treated seed (P < 0.0001), respectively. Results indicated that fungicide treatment improved soybean seed survival and germination in the field. The average of SGR of high-yielding soybean group was significantly higher than those of non-high-yielding soybean (P < 0.0001). The results indicated that high-yielding trait of each genotype was correlated with seed germination and survival. Under flood stress in the field, SGR means of untreated and fungicide-treated seed significantly decreased over eight flooding treatment times (P Flooding effect on germination between untreated and fungicide-treated seed was not significantly different (P = 0.1559). Furthermore, comparing the high-yielding and flood-tolerant soybean groups showed no difference in their SGR means over eight flooding treatment times (P = 0.7687 and P = 0.8490), indicating that soybean seed germination did not depend on genotype, yield, and flood tolerance trait, and seed treated by fungicide did not increase its germination in the field under the flood stress. Hence, it is necessary to develop new soybean seed pelleting to improve seed germination in the field under flooding conditions.
基金support from the Science Foundation of Ministry of Education of China(No.23YJC790190).
文摘This study examines the impact of the Belt and Road Initiative(BRI)on China's export potential at the product level.Using country–product-level data from the Centre d'Etudes Prospectives d'Informations Internationales-Base pour l'Analyse du Commerce International(CEPII-BACI),which includes 5,049 product types across 196 economies from 2007 to 2022,it explores the trade effects of the BRI and its mechanisms from the perspective of global value chains.The results indicate that the BRI has increased China's product export potential significantly to participating countires.The BRI has had the greatest impact on capital goods and labor-and capital-intensive industries.The effect has been most pronounced in China's exports to Southeast Asia,South Asia,and Europe.The mechanism analysis reveals that the BRI has improved the division of labor in the global value chains for participating countries along the BRI,strengthened China's position in their output supply chains,and stimulated the growth of China's exports.
基金supported by grants from the National Key Research and Development Program of China(Grant No.2018YFA0900800).
文摘Human adenoviruses(HAdvs)are major respiratory pathogens.Specifically,human adenovirus type 4(HAdV4)and human adenovirus type 7(HAdV7)are known for causing fever and pneumonia,with docu-mented cases of fatalities among the population.In recent years,HAdV4/HAdv7 has been implicated in caus-ing substantial outbreaks,leading to increased morbidity in multiple countries.Most HAdV4 and HAdV7 infections have been reported in North America,Asia,Europe,Africa,South America,Oceania,and the Middle East.Most fatalities occurred in North America(the United States)and Asia(China and Singapore).Engineered recombinant adenoviruses have played a crucial role as vaccine vectors.In this study,we con-structed a recombinant adenovirus,Ad4ITRmut-Ad7E3,and evaluated it in vitro and in vivo.We observed that the replication rate of Ad4ITRmut-Ad7E3 was lower than that of the RI-67 strain,indicating that the mutation of inverted terminal repeats(ITRs)weakened the replication ability of HAdV4.Immunization of BALB/c mice with the bivalent Ad4ITRmut-Ad7E3 vaccine strain,administered by intraperitoneal injection and oral gavage,resulted in the elicitation of neutralizing antibodies targeting HAdV4 and HAdv7.This finding not only pro-vides a novel method and technique for the efficient construction of a polyvalent recombinant adenovirus vac-cine candidate against HAdV4 and HAdv7 but also against other prevalent adenovirus serotypes such as HAdV3,HAdV11,HAdV14,and HAdv55,from various regions.
基金supported by the National Natural Science Foundation of China[82172398]Dalian Medical Key Specialty‘Dengfeng Plan’Construction Project and China Postdoctoral Science Foundation[2022M720616].
文摘Fracture is one of the most common traumatic diseases in clinical practice,and metal plates have always been the first choice for fracture treatment because of their high strength.However,the bone plates have high elastic modulus and do not match the biomechanics of human bone,which adversely affects callus formation and fracture healing.Moreover,the complex microenvironment in the human body can induce corrosion of metallic materials and release toxic ions,which reduces the biocompatibility of the bone plate,and may necessitate surgical removal of the implant.In this study,tantalum(Ta)was deposited on porous silicon carbide(SiC)scaffolds by chemical vapor deposition technology to prepare a novel porous tantalum(pTa)trabecular bone metal plate.The function of the novel bone plate was evaluated by implantation in an animal fracture model.The results showed that the novel bone plate was effective in fracture fixation,without breakage.Both X-ray and microcomputed tomography analysis showed indirect healing by both pTa trabecular bone metal plates and titanium(Ti)plates;however,elastic fixation and obvious callus formation were observed after fixation with pTa trabecular bone metal plates,indicating better bone repair.Histology showed that pTa promoted the formation of new bone and integrated well with the host bone.Therefore,this novel pTa trabecular bone metal plate has good prospects for application in treating fractures.
