Osmanthus fragrans Lour.is a well-known aromatic plant widely used as a food ingredient due to its unique floral fragrance and bioactive compounds.To fully utilize O.fragrans resources,we established an O.fragrans mul...Osmanthus fragrans Lour.is a well-known aromatic plant widely used as a food ingredient due to its unique floral fragrance and bioactive compounds.To fully utilize O.fragrans resources,we established an O.fragrans multi-omics database called the O.fragrans Information Resource(OfIR:http://yanglab.hzau.edu.cn/OfIR/home/).OfIR is a convenient and comprehensive multi-omics database that efficiently integrates phenotype and genetic variation from 127 O.fragrans cultivars,and provides many easy-to-use analysis tools,including primer design,sequence extraction,multi-sequence alignment,GO and KEGG enrichment analysis,variation annotation,and electronic PCR.Two case studies were used to demonstrate its power to mine candidate genetic variation sites or genes associated with specific traits or regulatory networks.In summary,the multi-omics database OfIR provides a convenient and user-friendly platform for researchers in mining functional genes and contributes to the genetic breeding of O.fragrans.展开更多
In the post-genome-wide association study era,multi-omics techniques have shown great power and poten-tial for candidate gene mining and functional genomics research.However,due to the lack of effective data integrati...In the post-genome-wide association study era,multi-omics techniques have shown great power and poten-tial for candidate gene mining and functional genomics research.However,due to the lack of effective data integration and multi-omics analysis platforms,such techniques have not still been applied widely in rape-seed,an important oil crop worldwide.Here,we report a rapeseed multi-omics database(BnlR;http:/l yanglab.hzau.edu.cn/BnlR),which provides datasets of six omics including genomics,transcriptomics,variomics,epigenetics,phenomics,and metabolomics,as well as numerous"variation-gene expression-phenotype"associations by using multiple statistical methods.In addition,a series of multi-omics search and analysis tools are integrated to facilitate the browsing and application of these datasets.BnlR is the most comprehensive multi-omics database for rapeseed so far,and two case studies demonstrated its power to mine candidate genes associated with specific traits and analyze their potential regulatory mechanisms.展开更多
Dear Editor,The transition from the vegetative to the reproductive phase of plant development,known as the floral transition,plays important roles in the plant life cycle.Flowering is a vulnerable but crucial phase fo...Dear Editor,The transition from the vegetative to the reproductive phase of plant development,known as the floral transition,plays important roles in the plant life cycle.Flowering is a vulnerable but crucial phase for building crop yield,and proper timing of this period is therefore vital for obtaining optimal yields(Jung and Muller,2009).Analysis of flowering time is currently an important research topic in several fields,including plant molecular genetics,evolutionary biology,ecology,and crop breeding(Huang et al.,2011).展开更多
基金supported by research grants provided by the National Natural Science Foundation of China(Grant Nos.32101581,32271951,and 32372754)the Hubei Provincial Central Leading Local Special Project(Grant No.2022BGE263)+3 种基金the Key Research and Science and Technology Program of Hubei Province(Grant No.2021BBA098)the Hubei Province Natural Science Foundation(Grant Nos.2023AFB1063 and 2024AFB1057)the Innovation Team Project from Hubei University of Science and Technology(Grant No.2022T02)a PhD grant from the Hubei University of Science and Technology(Grant Nos.BK202002and BK202419).
文摘Osmanthus fragrans Lour.is a well-known aromatic plant widely used as a food ingredient due to its unique floral fragrance and bioactive compounds.To fully utilize O.fragrans resources,we established an O.fragrans multi-omics database called the O.fragrans Information Resource(OfIR:http://yanglab.hzau.edu.cn/OfIR/home/).OfIR is a convenient and comprehensive multi-omics database that efficiently integrates phenotype and genetic variation from 127 O.fragrans cultivars,and provides many easy-to-use analysis tools,including primer design,sequence extraction,multi-sequence alignment,GO and KEGG enrichment analysis,variation annotation,and electronic PCR.Two case studies were used to demonstrate its power to mine candidate genetic variation sites or genes associated with specific traits or regulatory networks.In summary,the multi-omics database OfIR provides a convenient and user-friendly platform for researchers in mining functional genes and contributes to the genetic breeding of O.fragrans.
基金supported by the National Natural Science Foundation of China(32070559)the National Key Research and Development Plan of China(2021YFF1000100)+2 种基金the China Postdoctoral Science Foundation(2022M710875)the Hubei Hongshan Laboratory(2021HSZD004)and the Developing Bioinformatics Platform in Hainan Yazhou Bay Seed Lab(no.JBGS-B21HJ0001).
文摘In the post-genome-wide association study era,multi-omics techniques have shown great power and poten-tial for candidate gene mining and functional genomics research.However,due to the lack of effective data integration and multi-omics analysis platforms,such techniques have not still been applied widely in rape-seed,an important oil crop worldwide.Here,we report a rapeseed multi-omics database(BnlR;http:/l yanglab.hzau.edu.cn/BnlR),which provides datasets of six omics including genomics,transcriptomics,variomics,epigenetics,phenomics,and metabolomics,as well as numerous"variation-gene expression-phenotype"associations by using multiple statistical methods.In addition,a series of multi-omics search and analysis tools are integrated to facilitate the browsing and application of these datasets.BnlR is the most comprehensive multi-omics database for rapeseed so far,and two case studies demonstrated its power to mine candidate genes associated with specific traits and analyze their potential regulatory mechanisms.
基金supported by the National Key R&D Program of China (2022YFF1001400)the National Natural Science Foundation of China (32322061 and 32070559)Fundamental Research Funds for the Central University HZAU (2662023XXPY001).
文摘Dear Editor,The transition from the vegetative to the reproductive phase of plant development,known as the floral transition,plays important roles in the plant life cycle.Flowering is a vulnerable but crucial phase for building crop yield,and proper timing of this period is therefore vital for obtaining optimal yields(Jung and Muller,2009).Analysis of flowering time is currently an important research topic in several fields,including plant molecular genetics,evolutionary biology,ecology,and crop breeding(Huang et al.,2011).
