Taking salicylic acid as the active ingredient and 10%sodium hydroxide aqueous solution as the neutralizer,the best matrix for preparing gel was screened,and the salicylic acid aqueous gel was prepared.The properties,...Taking salicylic acid as the active ingredient and 10%sodium hydroxide aqueous solution as the neutralizer,the best matrix for preparing gel was screened,and the salicylic acid aqueous gel was prepared.The properties,pH value and viscosity were determined,and the stability,antibacterial activity and irritation were evaluated.The experimental results showed that the best gel matrix was cellulose,which had the best stability,could increase the solubility of salicylic acid in gel preparations,solved the problem of easy precipitation of salicylic acid crystals,enhanced the antibacterial activity,and reduced irritation,providing a reference for the application of salicylic acid in cosmetics.展开更多
文摘Taking salicylic acid as the active ingredient and 10%sodium hydroxide aqueous solution as the neutralizer,the best matrix for preparing gel was screened,and the salicylic acid aqueous gel was prepared.The properties,pH value and viscosity were determined,and the stability,antibacterial activity and irritation were evaluated.The experimental results showed that the best gel matrix was cellulose,which had the best stability,could increase the solubility of salicylic acid in gel preparations,solved the problem of easy precipitation of salicylic acid crystals,enhanced the antibacterial activity,and reduced irritation,providing a reference for the application of salicylic acid in cosmetics.
