This paper presents a P-Q coordination based highvoltage ride through(HVRT) control strategy for doubly fed induction generators(DFIGs) based on a combined Q-V control and P-V de-loading control. The active/reactive p...This paper presents a P-Q coordination based highvoltage ride through(HVRT) control strategy for doubly fed induction generators(DFIGs) based on a combined Q-V control and P-V de-loading control. The active/reactive power injection effect of DFIG on transient overvoltage is firstly analyzed and the reactive power capacity evaluation of DFIG considering its de-loading operation is then conducted. In the proposed strategy, the reactive power limit of DFIG can be flexibly extended during the transient process in coordination with its active power adjustment. As a result, the transient overvoltage caused by DC bipolar block can be effectively suppressed. Moreover, key outer loop parameters such as Q-V control coefficient and deloading coefficient can be determined based on the voltage level of point of common coupling(PCC) and the available power capacity of DFIG. Finally, case studies based on MATLAB/Simulink simulation are used to verify the effectiveness of the proposed control strategy.展开更多
Glioblastoma(GBM)causes nearly universal mortality as a result of the failure of conventional therapies including surgical resection,targeted radiation therapy,and chemotherapy.An increasingly important treatment opti...Glioblastoma(GBM)causes nearly universal mortality as a result of the failure of conventional therapies including surgical resection,targeted radiation therapy,and chemotherapy.An increasingly important treatment option is combining immunotherapy with other therapies in both preclinical and clinical studies.The central nervous system(CNS)has been historically considered an immune privileged area,but increasing evidence,including the recent rediscovery of meningeal lymphatic vessels(MLVs),has overturned this notion.MLVs are populated by multiple immune cells and connect the CNS to the periphery by draining cerebrospinal fluid with soluble CNS antigens and immune cells into cervical lymph nodes.In the past few years,more and more studies have indicated that MLVs are involved in the regulation of inflammation and the immune response in the pathogenesis of various CNS diseases including GBM.Here,we explore the critical interlinkages between MLVs and GBM therapies including chemotherapy,radiotherapy and immunotherapy,and propose the meningeal lymphatic vasculature as a general target for GBM therapy.展开更多
基金jointly supported by the National Natural Science Foundation of China (No.51677165,No.51837004)the National Key R&D Program of China (No.2017YFB0902000)。
文摘This paper presents a P-Q coordination based highvoltage ride through(HVRT) control strategy for doubly fed induction generators(DFIGs) based on a combined Q-V control and P-V de-loading control. The active/reactive power injection effect of DFIG on transient overvoltage is firstly analyzed and the reactive power capacity evaluation of DFIG considering its de-loading operation is then conducted. In the proposed strategy, the reactive power limit of DFIG can be flexibly extended during the transient process in coordination with its active power adjustment. As a result, the transient overvoltage caused by DC bipolar block can be effectively suppressed. Moreover, key outer loop parameters such as Q-V control coefficient and deloading coefficient can be determined based on the voltage level of point of common coupling(PCC) and the available power capacity of DFIG. Finally, case studies based on MATLAB/Simulink simulation are used to verify the effectiveness of the proposed control strategy.
基金supported by research grants from the National Natural Science Foundation of China(81930011,91739304,and 31821091)the National Key R&D Program of China(2019YFA0801603)+1 种基金supported by a Postdoctoral Fellowship of the Peking-Tsinghua Center for Life Sciencesthe China Postdoctoral Science Foundation(2022T150012).
文摘Glioblastoma(GBM)causes nearly universal mortality as a result of the failure of conventional therapies including surgical resection,targeted radiation therapy,and chemotherapy.An increasingly important treatment option is combining immunotherapy with other therapies in both preclinical and clinical studies.The central nervous system(CNS)has been historically considered an immune privileged area,but increasing evidence,including the recent rediscovery of meningeal lymphatic vessels(MLVs),has overturned this notion.MLVs are populated by multiple immune cells and connect the CNS to the periphery by draining cerebrospinal fluid with soluble CNS antigens and immune cells into cervical lymph nodes.In the past few years,more and more studies have indicated that MLVs are involved in the regulation of inflammation and the immune response in the pathogenesis of various CNS diseases including GBM.Here,we explore the critical interlinkages between MLVs and GBM therapies including chemotherapy,radiotherapy and immunotherapy,and propose the meningeal lymphatic vasculature as a general target for GBM therapy.
