Concern about health risks associated with rising obesity has become nearly universal, with the mean body mass index （BMI） and the prevalence of obese and overweight individuals increasing substantially worldwide du...Concern about health risks associated with rising obesity has become nearly universal, with the mean body mass index （BMI） and the prevalence of obese and overweight individuals increasing substantially worldwide during the previous three decades. Unfortunately, prevention and treatment of obesity and related complications have proven complex, and successful strategies to tackle this pathology remain limited. Epidemiological studies have highlighted potential environmental exposures, including diet, energy expenditure, early life influences, sleep deprivation, endocrine disruptors, chronic inflammation, and microbiome sta- tus, contributing to higher risk of obesity （Franks and McCarthy, 2016）. Among these, the microbiome has received extensive attention during the previous decade.展开更多
文摘Concern about health risks associated with rising obesity has become nearly universal, with the mean body mass index （BMI） and the prevalence of obese and overweight individuals increasing substantially worldwide during the previous three decades. Unfortunately, prevention and treatment of obesity and related complications have proven complex, and successful strategies to tackle this pathology remain limited. Epidemiological studies have highlighted potential environmental exposures, including diet, energy expenditure, early life influences, sleep deprivation, endocrine disruptors, chronic inflammation, and microbiome sta- tus, contributing to higher risk of obesity （Franks and McCarthy, 2016）. Among these, the microbiome has received extensive attention during the previous decade.
