Insect-derived traditional Chinese medicine(TCM)constitutes an essential component of TCM,with the earliest records found in“52 Bingfang”(Prescriptions of fifty-two diseases,which is one of the earliest Chinese medi...Insect-derived traditional Chinese medicine(TCM)constitutes an essential component of TCM,with the earliest records found in“52 Bingfang”(Prescriptions of fifty-two diseases,which is one of the earliest Chinese medical prescriptions).展开更多
Strongylium Kirby is one of the largest genera in the family Tenebrionidae.A new species belonging to this genus was found during our study of tenebrionid specimens from the Jiulong National Wetland Park,Zhejiang.The ...Strongylium Kirby is one of the largest genera in the family Tenebrionidae.A new species belonging to this genus was found during our study of tenebrionid specimens from the Jiulong National Wetland Park,Zhejiang.The new species,Strongylium jiulongense Yuan&Wang sp.nov.,is described.The habitus,illustrations and diagnosis with S.masumotoi Yuan&Ren,2006 are also presented.展开更多
The sixth generation(6G)mobile networks will reshape the world by offering instant,efficient,and intelligent hyper-connectivity,as envisioned by the previously proposed Ubiquitous-X 6G networks.Such hyper-massive and ...The sixth generation(6G)mobile networks will reshape the world by offering instant,efficient,and intelligent hyper-connectivity,as envisioned by the previously proposed Ubiquitous-X 6G networks.Such hyper-massive and global connectivity will introduce tremendous challenges into the operation and management of 6G networks,calling for revolutionary theories and technological innovations.To this end,we propose a new route to boost network capabilities toward a wisdom-evolutionary and primitive-concise network(WePCN)vision for the Ubiquitous-X 6G network.In particular,we aim to concretize the evolution path toward the WePCN by first conceiving a new semantic representation framework,namely semantic base,and then establishing an intelligent and efficient semantic communication(IE-SC)network architecture.In the IE-SC architecture,a semantic intelligence plane is employed to interconnect the semantic-empowered physical-bearing layer,network protocol layer,and application-intent layer via semantic information flows.The proposed architecture integrates artificial intelligence and network technologies to enable intelligent interactions among various communication objects in 6G.It features a lower bandwidth requirement,less redundancy,and more accurate intent identification.We also present a brief review of recent advances in semantic communications and highlight potential use cases,complemented by a range of open challenges for 6G.展开更多
本文通过对含有平面四配位氮团簇NLi_(3)E^(+)(E=N,P,As)和它们的平面四配位碳等电子体CLi_(3)E(E=N,P,As)进行详细地对比,研究了电子定域策略在设计含平面四配位氮团簇时的适应性.结果表明,NLi_(3)E^(+)团簇具有类似于CLi_(3)E的平面结...本文通过对含有平面四配位氮团簇NLi_(3)E^(+)(E=N,P,As)和它们的平面四配位碳等电子体CLi_(3)E(E=N,P,As)进行详细地对比,研究了电子定域策略在设计含平面四配位氮团簇时的适应性.结果表明,NLi_(3)E^(+)团簇具有类似于CLi_(3)E的平面结构,且其平面性都是由一个定域的π键决定的.然而,与CLi_(3)E相比,NLi_(3)E^(+)明显具有更高的电子结构稳定性、热力学稳定性和动力学稳定性,这可以从更宽的HOMO-LUMO能隙(4.58~4.68 eV vs.2.10~2.74 eV)在CCSD(T)/aug-cc-pVTZ水平下较低的能量和DFT水平下的分子动力学模拟中表现出的更好刚性得到验证.结果表明,电子定域策略可能更适合设计中心原子为较高电负性且更倾向于形成定域键的平面多配位分子.在这些团簇中,NLi_(3)E^(+)的稳定性最好,更适合进行气相合成及后续的质谱选择和光谱表征.展开更多
Glycyrrhizae Radix et Rhizoma,a traditional Chinese medicine also known as Gan Cao(GC),is frequently included in clinical prescriptions for the treatment of pneumonia.However,the pharmacological components of GC for p...Glycyrrhizae Radix et Rhizoma,a traditional Chinese medicine also known as Gan Cao(GC),is frequently included in clinical prescriptions for the treatment of pneumonia.However,the pharmacological components of GC for pneumonia treatment are rarely explored.Gan An He Ji oral liquid(GAHJ)has a simple composition and contains GC liquid extracts and paregoric,and has been used clinically for many years.Therefore,GAHJ was selected as a compound preparation for the study of GC in the treatment of pneumonia.We conducted an in vivo study of patients with pneumonia undergoing GAHJ treatments for three days.Using the intelligent mass spectrometry data-processing technologies to analyze the metabolism of GC in vivo,we obtained 168 related components of GC in humans,consisting of 24 prototype components and 144 metabolites,with 135 compounds screened in plasma and 82 in urine.After analysis of the metabolic transformation relationship and relative exposure,six components(liquiritin,liquiritigenin,glycyrrhizin,glycyrrhetinic acid,daidzin,and formononetin)were selected as potential effective components.The experimental results based on two animal pneumonia models and the inflammatory cell model showed that the mixture of these six components was effective in the treatment of pneumonia and lung injury and could effectively downregulate the level of inducible nitric oxide synthase(iNOS).Interestingly,glycyrrhetinic acid exhibited the strongest inhibition on iNOS and the highest exposure in vivo.The following molecular dynamic simulations indicated a strong bond between glycyrrhetinic acid and iNOS.Thus,the current study provides a pharmaceutical basis for GC and reveals the possible corresponding mechanisms in pneumonia treatment.展开更多
One new species,Uenostrongylium scaber Yuan Ren sp.nov.(China,Zhejiang),is described.Habitus and illustrations are provided,and a key to the genus Uenostrongylium is also given.
One new species of the genus Strongylium from Yunnan,China,S.dulongjiangense sp.nov.,is described.This new species is unique due to the yellow elytra and glabrous body.A list of the species in the genus Strongylium fr...One new species of the genus Strongylium from Yunnan,China,S.dulongjiangense sp.nov.,is described.This new species is unique due to the yellow elytra and glabrous body.A list of the species in the genus Strongylium from Yunnan and a key to the Chinese species of the S.rufipenne species group are provided.展开更多
Human-Computer dialogue systems provide a natural language based interface between human and computers. They are widely demanded in network information services, intelligent accompanying robots, and so on. A Human-Com...Human-Computer dialogue systems provide a natural language based interface between human and computers. They are widely demanded in network information services, intelligent accompanying robots, and so on. A Human-Computer dialogue system typically consists of three parts, namely Natural Language Understanding （NLU）, Dialogue Management （DM） and Natural Language Generation （NLG）. Each part has several different subtasks. Each subtask has been received lots of attentions, many improvements have been achieved on each subtask, respectively. But systems built in traditional pipeline way, where different subtasks are assembled sequently, suffered from some problems such as error accu- mulation and expanding, domain transferring. Therefore, researches on jointly modeling several subtasks in one part or cross different parts have been prompted greatly in recent years, especially the rapid developments on deep neural networks based joint models. There is even a few work aiming to integrate all subtasks of a dialogue system in a single model, namely end-to-end models. This paper introduces two basic frames of current dialogue systems and gives a brief survey on recent advances on variety subtasks at first, and then focuses on joint models for multiple subtasks of dialogues. We review several different joint models including integration of several subtasks inside NLU or NLG, jointly modeling cross NLG and DM, and jointly modeling through NLU, DM and NLG. Both advantages and problems of those joint models are discussed. We consider that the joint models, or end-to-end models, will be one important trend for developing Human-Computer dialogue systems.展开更多
A new species,Uenostrongylium gaoi Lin&Yuan sp.nov.from Guangdong,China,is described.It resembles Uenostrongylium scaber Yuan&Ren,2018 from Zhejiang due to the granulated upper edge of elytral punctures.Habitu...A new species,Uenostrongylium gaoi Lin&Yuan sp.nov.from Guangdong,China,is described.It resembles Uenostrongylium scaber Yuan&Ren,2018 from Zhejiang due to the granulated upper edge of elytral punctures.Habitus and illustrations are provided.展开更多
基金funded by the National Natural Science Foundation of China(Grant Nos.:82222068,82070423,82270348,and 82173779)the Innovation Team and Talents Cultivation Pro-gram of National Administration of Traditional Chinese Medicine,China(Grant No:ZYYCXTD-D-202206)+1 种基金Fujian Province Science and Technology Project,China(Grant Nos.:2021J01420479,2021J02058,2022J011374,and 2022J02057)Fundamental Research Funds for the Chinese Central Universities,China(Grant No.:20720230070).
文摘Insect-derived traditional Chinese medicine(TCM)constitutes an essential component of TCM,with the earliest records found in“52 Bingfang”(Prescriptions of fifty-two diseases,which is one of the earliest Chinese medical prescriptions).
基金supported by the National Natural Science Foundation of China(3246013131960113)+1 种基金the China Scholarship Council program(202308610209)the Natural Science Foundation of Shaanxi Province(2023-JC-YB-17).
文摘Strongylium Kirby is one of the largest genera in the family Tenebrionidae.A new species belonging to this genus was found during our study of tenebrionid specimens from the Jiulong National Wetland Park,Zhejiang.The new species,Strongylium jiulongense Yuan&Wang sp.nov.,is described.The habitus,illustrations and diagnosis with S.masumotoi Yuan&Ren,2006 are also presented.
基金the National Key Research and Development Program of China(2019YFC1511302)in part by the National Natural Science Foundation of China(61871057)in part by the Fundamental Research Funds for the Central Universities(2019XD-A13).
文摘The sixth generation(6G)mobile networks will reshape the world by offering instant,efficient,and intelligent hyper-connectivity,as envisioned by the previously proposed Ubiquitous-X 6G networks.Such hyper-massive and global connectivity will introduce tremendous challenges into the operation and management of 6G networks,calling for revolutionary theories and technological innovations.To this end,we propose a new route to boost network capabilities toward a wisdom-evolutionary and primitive-concise network(WePCN)vision for the Ubiquitous-X 6G network.In particular,we aim to concretize the evolution path toward the WePCN by first conceiving a new semantic representation framework,namely semantic base,and then establishing an intelligent and efficient semantic communication(IE-SC)network architecture.In the IE-SC architecture,a semantic intelligence plane is employed to interconnect the semantic-empowered physical-bearing layer,network protocol layer,and application-intent layer via semantic information flows.The proposed architecture integrates artificial intelligence and network technologies to enable intelligent interactions among various communication objects in 6G.It features a lower bandwidth requirement,less redundancy,and more accurate intent identification.We also present a brief review of recent advances in semantic communications and highlight potential use cases,complemented by a range of open challenges for 6G.
基金This work was supported by the National Natural Science Foundation of China(No.22073058)the Natural Science Foundation of Shanxi Province(No.201901D111018 and No.20210302124682)the Scientific and Technologial Innovation Programs of Higher Education Institutions in Shanxi(No.2020L0618).
基金supported by the National Natural Foudation of China(No.21720102006 and No.22073058)the High Performance Computer Center of Shanxi University.
文摘本文通过对含有平面四配位氮团簇NLi_(3)E^(+)(E=N,P,As)和它们的平面四配位碳等电子体CLi_(3)E(E=N,P,As)进行详细地对比,研究了电子定域策略在设计含平面四配位氮团簇时的适应性.结果表明,NLi_(3)E^(+)团簇具有类似于CLi_(3)E的平面结构,且其平面性都是由一个定域的π键决定的.然而,与CLi_(3)E相比,NLi_(3)E^(+)明显具有更高的电子结构稳定性、热力学稳定性和动力学稳定性,这可以从更宽的HOMO-LUMO能隙(4.58~4.68 eV vs.2.10~2.74 eV)在CCSD(T)/aug-cc-pVTZ水平下较低的能量和DFT水平下的分子动力学模拟中表现出的更好刚性得到验证.结果表明,电子定域策略可能更适合设计中心原子为较高电负性且更倾向于形成定域键的平面多配位分子.在这些团簇中,NLi_(3)E^(+)的稳定性最好,更适合进行气相合成及后续的质谱选择和光谱表征.
基金funded by the National Natural Science Foundation of China(Grant Nos.:82141215,82173694,82173779,82222068,and U1903119)Fujian Province Science and Technology Project(Grant Nos.:2021J011340 and 2020Y0013)Xiamen Municipal Bureau of Science and Technology Planning Project(Grant No.:3502Z2021YJ11).
文摘Glycyrrhizae Radix et Rhizoma,a traditional Chinese medicine also known as Gan Cao(GC),is frequently included in clinical prescriptions for the treatment of pneumonia.However,the pharmacological components of GC for pneumonia treatment are rarely explored.Gan An He Ji oral liquid(GAHJ)has a simple composition and contains GC liquid extracts and paregoric,and has been used clinically for many years.Therefore,GAHJ was selected as a compound preparation for the study of GC in the treatment of pneumonia.We conducted an in vivo study of patients with pneumonia undergoing GAHJ treatments for three days.Using the intelligent mass spectrometry data-processing technologies to analyze the metabolism of GC in vivo,we obtained 168 related components of GC in humans,consisting of 24 prototype components and 144 metabolites,with 135 compounds screened in plasma and 82 in urine.After analysis of the metabolic transformation relationship and relative exposure,six components(liquiritin,liquiritigenin,glycyrrhizin,glycyrrhetinic acid,daidzin,and formononetin)were selected as potential effective components.The experimental results based on two animal pneumonia models and the inflammatory cell model showed that the mixture of these six components was effective in the treatment of pneumonia and lung injury and could effectively downregulate the level of inducible nitric oxide synthase(iNOS).Interestingly,glycyrrhetinic acid exhibited the strongest inhibition on iNOS and the highest exposure in vivo.The following molecular dynamic simulations indicated a strong bond between glycyrrhetinic acid and iNOS.Thus,the current study provides a pharmaceutical basis for GC and reveals the possible corresponding mechanisms in pneumonia treatment.
基金supported by the National Natural Science Foundation of China(31501888)the Scientific Research Projects of the Shaanxi Education Department(15JK1837)the High-level University Construction Projects Funded Projects of Shaanxi Province(2012SXTS03)
文摘One new species,Uenostrongylium scaber Yuan Ren sp.nov.(China,Zhejiang),is described.Habitus and illustrations are provided,and a key to the genus Uenostrongylium is also given.
基金supported by the National Natural Science Foundation of China(31960113)the Doctoral Scientific Research Project of Yan’an University(YDBK2017-06)。
文摘One new species of the genus Strongylium from Yunnan,China,S.dulongjiangense sp.nov.,is described.This new species is unique due to the yellow elytra and glabrous body.A list of the species in the genus Strongylium from Yunnan and a key to the Chinese species of the S.rufipenne species group are provided.
文摘Human-Computer dialogue systems provide a natural language based interface between human and computers. They are widely demanded in network information services, intelligent accompanying robots, and so on. A Human-Computer dialogue system typically consists of three parts, namely Natural Language Understanding （NLU）, Dialogue Management （DM） and Natural Language Generation （NLG）. Each part has several different subtasks. Each subtask has been received lots of attentions, many improvements have been achieved on each subtask, respectively. But systems built in traditional pipeline way, where different subtasks are assembled sequently, suffered from some problems such as error accu- mulation and expanding, domain transferring. Therefore, researches on jointly modeling several subtasks in one part or cross different parts have been prompted greatly in recent years, especially the rapid developments on deep neural networks based joint models. There is even a few work aiming to integrate all subtasks of a dialogue system in a single model, namely end-to-end models. This paper introduces two basic frames of current dialogue systems and gives a brief survey on recent advances on variety subtasks at first, and then focuses on joint models for multiple subtasks of dialogues. We review several different joint models including integration of several subtasks inside NLU or NLG, jointly modeling cross NLG and DM, and jointly modeling through NLU, DM and NLG. Both advantages and problems of those joint models are discussed. We consider that the joint models, or end-to-end models, will be one important trend for developing Human-Computer dialogue systems.
基金supported by the National Natural Science Foundation of China(31960113)the Doctoral Scientific Research Project of Yan’an University(YDBK2017-06)GDAS Special Project of Science and Technology Development(2020GDASYL-20200102021,2020GDASYL-20200301003)。
文摘A new species,Uenostrongylium gaoi Lin&Yuan sp.nov.from Guangdong,China,is described.It resembles Uenostrongylium scaber Yuan&Ren,2018 from Zhejiang due to the granulated upper edge of elytral punctures.Habitus and illustrations are provided.
