Objective： To observe the efficacy and safety of Jingui Shengqi Pill （金匮肾气丸, JSP） in treating partial androgen deficiency in aging males （PADAM）, and to explore the new approach in improving the quality of l...Objective： To observe the efficacy and safety of Jingui Shengqi Pill （金匮肾气丸, JSP） in treating partial androgen deficiency in aging males （PADAM）, and to explore the new approach in improving the quality of life in PADAM patients. Methods： Forty patients with PADAM were treated with JSP, the efficacy was evaluated with international index of erectile function （IIEF） scoring, PADAM questionnaire scoring, hormone, prostatic specific antigen （PSA）, etc., and the data before treatment were compared with those after treatment in the same group. Results： After 3 months of treatment, PADAM scoring and IIEF scoring were all significantly improved. Symptoms regarding physical ability, vasomotion, and psychical and mental condition all got improved more markedly than symptoms regarding sexual hypofunction. The serum level of testosterone was 3.85±0.36 before treatment and 5.02±0.83 after treatmnet （P〈0.05）; luteinizing hormone of 7.33±2.14 and 4.84±1.43 （P〈0.01）, follicule-stimulating hormone of 10.22±4.48 and 6.47±3.28 （P〈0.01）, respectively. The level of PSA failed to change significantly （1.94±0.55 and 2.06±0.47, P〉0.05）. Conclusion： JSP is effective and safe in treating PADAM, the mechanism of it is different from supplementing extrinsic androgen. It may have produced the effect by means of favorably regulating the condition of sex hormone to improve the balance of pituitary-sex gland axis, so it has more extensive clinical application.展开更多
AIM: To assess the safety and feasibility of peroral esophageal myotomy(POEM) in patients with achalasia.METHODS: From January 2012 to March 2014, 50 patients(28 men, 22 women; mean age: 42.8 years, range: 14-70 years...AIM: To assess the safety and feasibility of peroral esophageal myotomy(POEM) in patients with achalasia.METHODS: From January 2012 to March 2014, 50 patients(28 men, 22 women; mean age: 42.8 years, range: 14-70 years) underwent POEM. Pre- and postoperative symptoms were quantified using the Eckardt scoring system. Barium swallow and esophagogastroscopy were performed before and after POEM, respectively. Esophageal motility was evaluated in all patients, both preoperatively and one month after POEM treatment, using a high-resolution manometry system. Manometry data, Eckardt scores, lower esophageal sphincter pressure and barium swallow results were used to evaluate the effect of the procedure.RESULTS: POEM was successfully completed for all patients. The mean procedure time was 55.4 ± 17.3 min and the mean total length of myotomy of the circular esophagus was 10.5 ± 2.6 cm. No specific complications occurred, with the exception of two patients that developed as ymptomatic pneumomediastinum and subcutaneous emphysema. Clinical improvement in symptoms was achieved in all patients. Approximately 77.5% of patients experienced weight gain 6 mo after POEM, with an average of 4.78 kg(range: 2-15 kg). The lower esophageal sphincter resting pressure, four second integrated relaxation pressure and Eckardt scores were all significantly reduced after POEM(Ps < 0.05). A small segment of proximal esophageal peristalsis appeared postoperatively in two patients, but without normal esophageal peristalsis. The average diameter of the esophageal lumen decreased significantly from 4.39 to 3.09 cm(P < 0.01). CONCLUSION: POEM can relieve achalasia symptoms, improve gastroesophageal junction relaxation and restore esophageal body motility function, but not normal esophageal peristalsis.展开更多
The conservative form and singular perturbed ordinary differential equation with periodic boundary value problem were studied, and a conservative difference scheme was constructed. Using the method of decomposing the ...The conservative form and singular perturbed ordinary differential equation with periodic boundary value problem were studied, and a conservative difference scheme was constructed. Using the method of decomposing the singular term from its solution and combining an asymptotic expansion of the equation, it is proved that the scheme converges uniformly to the solution of differential equation with order one.展开更多
The role of auxiliary LAB as vehicle in dyeing polyester/wool blends with disperse dyes is described. Dye exhaustion and bonding on polyester/wool samples are studied under different experimental conditions - the LAB ...The role of auxiliary LAB as vehicle in dyeing polyester/wool blends with disperse dyes is described. Dye exhaustion and bonding on polyester/wool samples are studied under different experimental conditions - the LAB amount, the temperature and pH value- to achieve optimum conditions. The results are compared with those obtained with and without conventional dyeing auxiliary products. Although dye exhaustion is higher in the presence of commercial carriers, the dye bonded increases markedly in the presence of auxiliary LAB in both fibers. The role played by auxiliary LAB in polyester/wool blend dyeing can provide a new method for this process.展开更多
In recent twenty years, much numerical simulation work has been done on the evolution of Qinghai-Xizang (Tibetan) plateau. In this paper some principal numerical models and results are reviewed and analyzed. The earli...In recent twenty years, much numerical simulation work has been done on the evolution of Qinghai-Xizang (Tibetan) plateau. In this paper some principal numerical models and results are reviewed and analyzed. The earlier plane stress or plane strain model has much discrepancy with the actual deformation of Qinghai-Xizang plateau, such as the thickening of Tibetan crust and the lateral extrusion of Tibet along strike-slip faults. The thin viscous sheet model and the thin-plate model may simulate the change of the crustal thickness and the deformation pro-duced by gravitational force. It is suitable for studying the large-scale and long-time deformation. The influence of faults on the deformation of Tibetan plateau should be further studied.展开更多
The crystal structure of novel coordination polymer with excellent characteristic luminescence of Eu3+, the three-dimentional network of {Eu2(p-BDC)3(Phen)2(H2O)2}n is presented.
A New View on Sino-U. S. Relations Sino-U. S. relations seem to have emerged into a more positive light in recent years. China and the United States have sustained a strong relationship since 9/11, for the simple reas...A New View on Sino-U. S. Relations Sino-U. S. relations seem to have emerged into a more positive light in recent years. China and the United States have sustained a strong relationship since 9/11, for the simple reason that international relations at present require展开更多
A method for modeling broadcast protocols in OPNET is introduced by illustrating a simulation of a new real-time Ethernet MAC protocol. The details of network models in OPNET are given and the procedure in modeling is...A method for modeling broadcast protocols in OPNET is introduced by illustrating a simulation of a new real-time Ethernet MAC protocol. The details of network models in OPNET are given and the procedure in modeling is introduced. Simulation results verify that the protocol is correct and efficient.展开更多
A discrete variable structure control(DVSC) method for the linear time invariant systems with time delay was presented. The continuous time delay systems are first transformed into the standard discrete form which con...A discrete variable structure control(DVSC) method for the linear time invariant systems with time delay was presented. The continuous time delay systems are first transformed into the standard discrete form which contains no time delay by augmenting the state variables. Then the switching surface is determined by using the ideal quasi sliding mode. As it is difficult for the state trajectory to reach the switching surface exactly, the reaching condition in the form of approach law is used to design the controller. The deduced switching surface and controller contain not only the current step of state feedback but also some former steps of controls. Stability analysis with and without time delay information is also investigated in this paper. Numerical simulation was carried out to demonstrate the effectiveness and feasibility of the presented control method.展开更多
A new active control method was proposed, in which the analytical control law was deduced by using a step by step integral method to differential equation of motion under the condition of static error being zero. This...A new active control method was proposed, in which the analytical control law was deduced by using a step by step integral method to differential equation of motion under the condition of static error being zero. This control law is terse in mathematical expression and convenient for practical use. The simulation results demonstrate that the proposed method can provide much more remarkable peak response reduction of seismically excited structures than the classical LQR method.展开更多
An existence theorem of maximal elements for a new type of preference correspondences which are Q(0)-majorized is given. Then some existence theorems of equilibrium for abstract economy and qualitative game in which t...An existence theorem of maximal elements for a new type of preference correspondences which are Q(0)-majorized is given. Then some existence theorems of equilibrium for abstract economy and qualitative game in which the constraint or preference correspondences are Q(0)-majorized are obtained in locally convex topological vector spaces.展开更多
How to solve unit commitment and load dispatch of power system by genetic algorithms is discussed in this paper. A combination encoding scheme of binary encoding and floating number encoding and corresponding genetic ...How to solve unit commitment and load dispatch of power system by genetic algorithms is discussed in this paper. A combination encoding scheme of binary encoding and floating number encoding and corresponding genetic operators are developed. Meanwhile a contract mapping genetic algorithm is used to enhance traditional GA’s convergence. The result of a practical example shows that this algorithm is effective.展开更多
Considering the difficulty of creating water quality model for activated sludge system, a typical BP artificial neural network model has been established to simulate the operation of a waste water treatment facilities...Considering the difficulty of creating water quality model for activated sludge system, a typical BP artificial neural network model has been established to simulate the operation of a waste water treatment facilities. The comparison of prediction results with the on-spot measurements shows the model, the model is accurate and this model can also be used to realize intelligentized on-line control of the wastewater processing process.展开更多
Cubic boron nitride(c-BN) films were deposited on W6Mo5Cr4V2 high speed steel(HSS) substrate implanted with boron ion by RF-magnetron sputtering. The films were analyzed by the bending beam method, scratch test, XPS a...Cubic boron nitride(c-BN) films were deposited on W6Mo5Cr4V2 high speed steel(HSS) substrate implanted with boron ion by RF-magnetron sputtering. The films were analyzed by the bending beam method, scratch test, XPS and AFM. The experimental results show that the implantation of boron atom can reduce the internal stress and improve the adhesion strength of the films. The critical load of scratch test rises to 27.45 N, compared to 1.75 N of c-BN film on the unimplanted HSS. The AFM shows that the surface of the c-BN film on the implanted HSS is low in roughness and small in grain size. Then the composition of the boron implanted layer was analyzed by the XPS. And the influence of the boron implanted layer on the internal stress and adhesion strength of c-BN films were investigated.展开更多
A co-evolutional immune algorithm for the optimization of a function with real parameters is de-scribed.It uses a cooperative co-evolution of two populations,one is a population of antibodies and theother is a populat...A co-evolutional immune algorithm for the optimization of a function with real parameters is de-scribed.It uses a cooperative co-evolution of two populations,one is a population of antibodies and theother is a population of successful mutation vectors.These two population evolve together to improve thediversity of the antibodies.The algorithm described is then tested on a suite of optimization problems.The results show that on most of test functions,this algorithm can converge to the global optimum atquicker rate in a given range,the performance of optimization is improved effetely.展开更多
An incremental time-delay neural network based on synapse growth, which is suitable for dynamic control and learning of autonomous robots, is proposed to improve the learning and retrieving performance of dynamical re...An incremental time-delay neural network based on synapse growth, which is suitable for dynamic control and learning of autonomous robots, is proposed to improve the learning and retrieving performance of dynamical recurrent associative memory architecture. The model allows steady and continuous establishment of associative memory for spatio-temporal regularities and time series in discrete sequence of inputs. The inserted hidden units can be taken as the long-term memories that expand the capacity of network and sometimes may fade away under certain condition. Preliminary experiment has shown that this incremental network may be a promising approach to endow autonomous robots with the ability of adapting to new data without destroying the learned patterns. The system also benefits from its potential chaos character for emergence.展开更多
The goal in reinforcement learning is to learn the value of state-action pair in order to maximize the total reward. For continuous states and actions in the real world, the representation of value functions is critic...The goal in reinforcement learning is to learn the value of state-action pair in order to maximize the total reward. For continuous states and actions in the real world, the representation of value functions is critical. Furthermore, the samples in value functions are sequentially obtained. Therefore, an online sup-port vector regression （OSVR） is set up, which is a function approximator to estimate value functions in reinforcement learning. OSVR updates the regression function by analyzing the possible variation of sup-port vector sets after new samples are inserted to the training set. To evaluate the OSVR learning ability, it is applied to the mountain-car task. The simulation results indicate that the OSVR has a preferable con- vergence speed and can solve continuous problems that are infeasible using lookup table.展开更多
文摘Objective： To observe the efficacy and safety of Jingui Shengqi Pill （金匮肾气丸, JSP） in treating partial androgen deficiency in aging males （PADAM）, and to explore the new approach in improving the quality of life in PADAM patients. Methods： Forty patients with PADAM were treated with JSP, the efficacy was evaluated with international index of erectile function （IIEF） scoring, PADAM questionnaire scoring, hormone, prostatic specific antigen （PSA）, etc., and the data before treatment were compared with those after treatment in the same group. Results： After 3 months of treatment, PADAM scoring and IIEF scoring were all significantly improved. Symptoms regarding physical ability, vasomotion, and psychical and mental condition all got improved more markedly than symptoms regarding sexual hypofunction. The serum level of testosterone was 3.85±0.36 before treatment and 5.02±0.83 after treatmnet （P〈0.05）; luteinizing hormone of 7.33±2.14 and 4.84±1.43 （P〈0.01）, follicule-stimulating hormone of 10.22±4.48 and 6.47±3.28 （P〈0.01）, respectively. The level of PSA failed to change significantly （1.94±0.55 and 2.06±0.47, P〉0.05）. Conclusion： JSP is effective and safe in treating PADAM, the mechanism of it is different from supplementing extrinsic androgen. It may have produced the effect by means of favorably regulating the condition of sex hormone to improve the balance of pituitary-sex gland axis, so it has more extensive clinical application.
文摘AIM: To assess the safety and feasibility of peroral esophageal myotomy(POEM) in patients with achalasia.METHODS: From January 2012 to March 2014, 50 patients(28 men, 22 women; mean age: 42.8 years, range: 14-70 years) underwent POEM. Pre- and postoperative symptoms were quantified using the Eckardt scoring system. Barium swallow and esophagogastroscopy were performed before and after POEM, respectively. Esophageal motility was evaluated in all patients, both preoperatively and one month after POEM treatment, using a high-resolution manometry system. Manometry data, Eckardt scores, lower esophageal sphincter pressure and barium swallow results were used to evaluate the effect of the procedure.RESULTS: POEM was successfully completed for all patients. The mean procedure time was 55.4 ± 17.3 min and the mean total length of myotomy of the circular esophagus was 10.5 ± 2.6 cm. No specific complications occurred, with the exception of two patients that developed as ymptomatic pneumomediastinum and subcutaneous emphysema. Clinical improvement in symptoms was achieved in all patients. Approximately 77.5% of patients experienced weight gain 6 mo after POEM, with an average of 4.78 kg(range: 2-15 kg). The lower esophageal sphincter resting pressure, four second integrated relaxation pressure and Eckardt scores were all significantly reduced after POEM(Ps < 0.05). A small segment of proximal esophageal peristalsis appeared postoperatively in two patients, but without normal esophageal peristalsis. The average diameter of the esophageal lumen decreased significantly from 4.39 to 3.09 cm(P < 0.01). CONCLUSION: POEM can relieve achalasia symptoms, improve gastroesophageal junction relaxation and restore esophageal body motility function, but not normal esophageal peristalsis.
文摘The conservative form and singular perturbed ordinary differential equation with periodic boundary value problem were studied, and a conservative difference scheme was constructed. Using the method of decomposing the singular term from its solution and combining an asymptotic expansion of the equation, it is proved that the scheme converges uniformly to the solution of differential equation with order one.
文摘The role of auxiliary LAB as vehicle in dyeing polyester/wool blends with disperse dyes is described. Dye exhaustion and bonding on polyester/wool samples are studied under different experimental conditions - the LAB amount, the temperature and pH value- to achieve optimum conditions. The results are compared with those obtained with and without conventional dyeing auxiliary products. Although dye exhaustion is higher in the presence of commercial carriers, the dye bonded increases markedly in the presence of auxiliary LAB in both fibers. The role played by auxiliary LAB in polyester/wool blend dyeing can provide a new method for this process.
文摘In recent twenty years, much numerical simulation work has been done on the evolution of Qinghai-Xizang (Tibetan) plateau. In this paper some principal numerical models and results are reviewed and analyzed. The earlier plane stress or plane strain model has much discrepancy with the actual deformation of Qinghai-Xizang plateau, such as the thickening of Tibetan crust and the lateral extrusion of Tibet along strike-slip faults. The thin viscous sheet model and the thin-plate model may simulate the change of the crustal thickness and the deformation pro-duced by gravitational force. It is suitable for studying the large-scale and long-time deformation. The influence of faults on the deformation of Tibetan plateau should be further studied.
基金We are grateful to State Key Project of Foundational Research of China (G1998061308) and the National Natural Science Foundation of China (G200071004) for support of this research.
文摘The crystal structure of novel coordination polymer with excellent characteristic luminescence of Eu3+, the three-dimentional network of {Eu2(p-BDC)3(Phen)2(H2O)2}n is presented.
文摘A New View on Sino-U. S. Relations Sino-U. S. relations seem to have emerged into a more positive light in recent years. China and the United States have sustained a strong relationship since 9/11, for the simple reason that international relations at present require
文摘A method for modeling broadcast protocols in OPNET is introduced by illustrating a simulation of a new real-time Ethernet MAC protocol. The details of network models in OPNET are given and the procedure in modeling is introduced. Simulation results verify that the protocol is correct and efficient.
文摘A discrete variable structure control(DVSC) method for the linear time invariant systems with time delay was presented. The continuous time delay systems are first transformed into the standard discrete form which contains no time delay by augmenting the state variables. Then the switching surface is determined by using the ideal quasi sliding mode. As it is difficult for the state trajectory to reach the switching surface exactly, the reaching condition in the form of approach law is used to design the controller. The deduced switching surface and controller contain not only the current step of state feedback but also some former steps of controls. Stability analysis with and without time delay information is also investigated in this paper. Numerical simulation was carried out to demonstrate the effectiveness and feasibility of the presented control method.
文摘A new active control method was proposed, in which the analytical control law was deduced by using a step by step integral method to differential equation of motion under the condition of static error being zero. This control law is terse in mathematical expression and convenient for practical use. The simulation results demonstrate that the proposed method can provide much more remarkable peak response reduction of seismically excited structures than the classical LQR method.
文摘An existence theorem of maximal elements for a new type of preference correspondences which are Q(0)-majorized is given. Then some existence theorems of equilibrium for abstract economy and qualitative game in which the constraint or preference correspondences are Q(0)-majorized are obtained in locally convex topological vector spaces.
文摘How to solve unit commitment and load dispatch of power system by genetic algorithms is discussed in this paper. A combination encoding scheme of binary encoding and floating number encoding and corresponding genetic operators are developed. Meanwhile a contract mapping genetic algorithm is used to enhance traditional GA’s convergence. The result of a practical example shows that this algorithm is effective.
文摘Considering the difficulty of creating water quality model for activated sludge system, a typical BP artificial neural network model has been established to simulate the operation of a waste water treatment facilities. The comparison of prediction results with the on-spot measurements shows the model, the model is accurate and this model can also be used to realize intelligentized on-line control of the wastewater processing process.
基金National Natural Science Foundation ofChina(No.59971065)
文摘Cubic boron nitride(c-BN) films were deposited on W6Mo5Cr4V2 high speed steel(HSS) substrate implanted with boron ion by RF-magnetron sputtering. The films were analyzed by the bending beam method, scratch test, XPS and AFM. The experimental results show that the implantation of boron atom can reduce the internal stress and improve the adhesion strength of the films. The critical load of scratch test rises to 27.45 N, compared to 1.75 N of c-BN film on the unimplanted HSS. The AFM shows that the surface of the c-BN film on the implanted HSS is low in roughness and small in grain size. Then the composition of the boron implanted layer was analyzed by the XPS. And the influence of the boron implanted layer on the internal stress and adhesion strength of c-BN films were investigated.
基金Supported by the National Fundamental Research Project(A1420060159)
文摘A co-evolutional immune algorithm for the optimization of a function with real parameters is de-scribed.It uses a cooperative co-evolution of two populations,one is a population of antibodies and theother is a population of successful mutation vectors.These two population evolve together to improve thediversity of the antibodies.The algorithm described is then tested on a suite of optimization problems.The results show that on most of test functions,this algorithm can converge to the global optimum atquicker rate in a given range,the performance of optimization is improved effetely.
文摘An incremental time-delay neural network based on synapse growth, which is suitable for dynamic control and learning of autonomous robots, is proposed to improve the learning and retrieving performance of dynamical recurrent associative memory architecture. The model allows steady and continuous establishment of associative memory for spatio-temporal regularities and time series in discrete sequence of inputs. The inserted hidden units can be taken as the long-term memories that expand the capacity of network and sometimes may fade away under certain condition. Preliminary experiment has shown that this incremental network may be a promising approach to endow autonomous robots with the ability of adapting to new data without destroying the learned patterns. The system also benefits from its potential chaos character for emergence.
文摘The goal in reinforcement learning is to learn the value of state-action pair in order to maximize the total reward. For continuous states and actions in the real world, the representation of value functions is critical. Furthermore, the samples in value functions are sequentially obtained. Therefore, an online sup-port vector regression （OSVR） is set up, which is a function approximator to estimate value functions in reinforcement learning. OSVR updates the regression function by analyzing the possible variation of sup-port vector sets after new samples are inserted to the training set. To evaluate the OSVR learning ability, it is applied to the mountain-car task. The simulation results indicate that the OSVR has a preferable con- vergence speed and can solve continuous problems that are infeasible using lookup table.
