为了提高豆渣的综合利用价值,减少资源浪费,以豆渣为原料,与大米粉、玉米淀粉及单脂肪酸甘油酯均匀混合后,通过双螺杆挤压机制备豆渣重组米。豆渣重组米经过挤压使部分不溶性膳食纤维转化成可溶性膳食纤维,且膳食纤维含量明显高于普通...为了提高豆渣的综合利用价值,减少资源浪费,以豆渣为原料,与大米粉、玉米淀粉及单脂肪酸甘油酯均匀混合后,通过双螺杆挤压机制备豆渣重组米。豆渣重组米经过挤压使部分不溶性膳食纤维转化成可溶性膳食纤维,且膳食纤维含量明显高于普通大米。豆渣重组米的水溶性指数、吸水指数、持水指数、吸油指数和膨胀指数分别是(469.25±1.77)g/g、(5.42±0.05)%、(7.77±0.03)g/g、(3.68±0.11)g/g、(8.58±0.11)mL/g,较普通大米有显著性提高(P<0.05)。豆渣重组米降低了小鼠体质量的增加量,增加了小鼠的葡萄糖耐受量,豆渣重组米组小鼠的血糖曲线下面积为(1313.83±45.17)mmol·h/L,明显低于空白组。通过16 s rDNA基因组学分析,发现豆渣重组米组小鼠肠道菌群的物种数(4625.04)、Chao1指数(5124.28)、Shannon指数(8.70)均高于空白组,豆渣重组米增加了肠道菌群的丰富度和多样性,提高了拟杆菌门的丰度。展开更多
Because of their excellent low-temperature(−15 to−40℃)tolerance,sodium-ion batteries are emerging as a complement to lithium-ion batteries for use in extremely cold environments(e.g.high-latitude areas).Hard carbon h...Because of their excellent low-temperature(−15 to−40℃)tolerance,sodium-ion batteries are emerging as a complement to lithium-ion batteries for use in extremely cold environments(e.g.high-latitude areas).Hard carbon has a high low-voltage sodium storage capacity and a good initial efficiency,making it one of the most promising anode materials for sodium-ion batteries.It has a complex structure,featuring closed pores,nano graphitic domains,and surface functional groups.The sodium storage sites in hard carbon are reviewed as are the widely accepted sodium storage mechanisms.The main factors contributing to the degradation of the good low-temperature performance in hard carbon anodes are considered,including sodium dendrite formation,low ion diffusion rates,and surface-side reactions.Finally,strategies to increase the low-temperature sodium storage performance of hard carbon anodes are summarized,including bulk structure design,and improvements in interfaces and cut-off voltage.Guidance is provided for improving the low-temperature performance of hard carbon anodes to accelerate the development of these batteries.展开更多
目的:探讨术前淋巴细胞/单核细胞比值(ratio of lymphocyte to monocyte,LMR)与结直肠癌临床特征及预后的相关性。方法:回顾性分析2010年1月—2012年5月在上海交通大学医学院附属仁济医院胃肠外科行手术治疗且随访资料完整的218例结直...目的:探讨术前淋巴细胞/单核细胞比值(ratio of lymphocyte to monocyte,LMR)与结直肠癌临床特征及预后的相关性。方法:回顾性分析2010年1月—2012年5月在上海交通大学医学院附属仁济医院胃肠外科行手术治疗且随访资料完整的218例结直肠患者的临床病理资料。根据受试者工作特征(receiver operating characteristic,ROC)曲线结果确定LMR预测术后5年总生存率的最佳截断值(cut-ovalue),将患者分为低LMR组和高LMR组。比较2组临床病理特征的差异。应用Kaplan-Meier法计算生存率,并采用log-rank检验对组间生存率进行比较,COX比例风险模型分析结直肠患者预后的影响因素。结果:术前LMR预测术后5年总生存率的最佳截断值为4.7,由此将入组患者分为2组,即高LMR组(LMR>4.7)和低LMR组(LMR≤4.7)。2组患者的T分期和临床分期差异有统计学意义(P值均<0.05)。术前高LMR组和低LMR组结直肠癌患者的术后5年总生存率分别为72.2%和48.6%(P=0.008)。预后的单因素分析结果显示,N分期、临床分期、术前癌胚抗原水平和术前LMR与结直肠癌患者术后5年总生存率相关(P值均<0.05)。多因素分析结果显示,N分期、临床分期和术前LMR均是结直肠癌患者术后5年总生存率的独立预后因素(P值均<0.05)。结论:术前LMR≤4.7提示结直肠癌患者预后较差。术前LMR可作为结直肠癌患者的独立预后因素。展开更多
Smart specialization is a regional development strategy that identifies regional innovation advantages through the analysis of cluster networks,while strengthening both intra-cluster and inter-cluster technological li...Smart specialization is a regional development strategy that identifies regional innovation advantages through the analysis of cluster networks,while strengthening both intra-cluster and inter-cluster technological linkages to promote coordinated regional development.Drawing on branch office flow and patent cooperation data,and employing methods such as the Expectation-Maximization(EM)clustering algorithm and the‘Product Space’approach,this study investigates innovation and technological linkages both within and across industrial clusters.The key findings are as follows.First,Jiangsu’s clusters demonstrate two patterns:closely integrated industrial networks in southern cities like Suzhou,fostering strong industrial resilience,and distinct technological boundaries in northern and central cities like Yancheng,resulting in weaker integration.Second,the cluster network exhibits a single-core structure at the municipal level,centered around Nanjing,with a multi-tiered hierarchy at the district level.Third,innovation linkages between clusters follow a dual-core structure,with Nanjing and Suzhou as central hubs.In this structure,large enterprises in Nanjing and small and medium-sized enterprises(SMEs)in Suzhou reflect complementary industrial characteristics.Finally,both technology-intensive and low-tech manufacturing industries show a higher propensity for cross-regional innovation,with some cities demonstrating significant advantages in high-tech industries.Grounded in the framework of smart specialization,this study conducts an in-depth analysis of innovation and technological linkages within cluster networks at the industrial level,offering scientific insights to support the localized implementation of smart specialization strategies in the Chinese context.展开更多
文摘为了提高豆渣的综合利用价值,减少资源浪费,以豆渣为原料,与大米粉、玉米淀粉及单脂肪酸甘油酯均匀混合后,通过双螺杆挤压机制备豆渣重组米。豆渣重组米经过挤压使部分不溶性膳食纤维转化成可溶性膳食纤维,且膳食纤维含量明显高于普通大米。豆渣重组米的水溶性指数、吸水指数、持水指数、吸油指数和膨胀指数分别是(469.25±1.77)g/g、(5.42±0.05)%、(7.77±0.03)g/g、(3.68±0.11)g/g、(8.58±0.11)mL/g,较普通大米有显著性提高(P<0.05)。豆渣重组米降低了小鼠体质量的增加量,增加了小鼠的葡萄糖耐受量,豆渣重组米组小鼠的血糖曲线下面积为(1313.83±45.17)mmol·h/L,明显低于空白组。通过16 s rDNA基因组学分析,发现豆渣重组米组小鼠肠道菌群的物种数(4625.04)、Chao1指数(5124.28)、Shannon指数(8.70)均高于空白组,豆渣重组米增加了肠道菌群的丰富度和多样性,提高了拟杆菌门的丰度。
文摘Because of their excellent low-temperature(−15 to−40℃)tolerance,sodium-ion batteries are emerging as a complement to lithium-ion batteries for use in extremely cold environments(e.g.high-latitude areas).Hard carbon has a high low-voltage sodium storage capacity and a good initial efficiency,making it one of the most promising anode materials for sodium-ion batteries.It has a complex structure,featuring closed pores,nano graphitic domains,and surface functional groups.The sodium storage sites in hard carbon are reviewed as are the widely accepted sodium storage mechanisms.The main factors contributing to the degradation of the good low-temperature performance in hard carbon anodes are considered,including sodium dendrite formation,low ion diffusion rates,and surface-side reactions.Finally,strategies to increase the low-temperature sodium storage performance of hard carbon anodes are summarized,including bulk structure design,and improvements in interfaces and cut-off voltage.Guidance is provided for improving the low-temperature performance of hard carbon anodes to accelerate the development of these batteries.
文摘目的:探讨术前淋巴细胞/单核细胞比值(ratio of lymphocyte to monocyte,LMR)与结直肠癌临床特征及预后的相关性。方法:回顾性分析2010年1月—2012年5月在上海交通大学医学院附属仁济医院胃肠外科行手术治疗且随访资料完整的218例结直肠患者的临床病理资料。根据受试者工作特征(receiver operating characteristic,ROC)曲线结果确定LMR预测术后5年总生存率的最佳截断值(cut-ovalue),将患者分为低LMR组和高LMR组。比较2组临床病理特征的差异。应用Kaplan-Meier法计算生存率,并采用log-rank检验对组间生存率进行比较,COX比例风险模型分析结直肠患者预后的影响因素。结果:术前LMR预测术后5年总生存率的最佳截断值为4.7,由此将入组患者分为2组,即高LMR组(LMR>4.7)和低LMR组(LMR≤4.7)。2组患者的T分期和临床分期差异有统计学意义(P值均<0.05)。术前高LMR组和低LMR组结直肠癌患者的术后5年总生存率分别为72.2%和48.6%(P=0.008)。预后的单因素分析结果显示,N分期、临床分期、术前癌胚抗原水平和术前LMR与结直肠癌患者术后5年总生存率相关(P值均<0.05)。多因素分析结果显示,N分期、临床分期和术前LMR均是结直肠癌患者术后5年总生存率的独立预后因素(P值均<0.05)。结论:术前LMR≤4.7提示结直肠癌患者预后较差。术前LMR可作为结直肠癌患者的独立预后因素。
基金Under the auspices of the National Natural Science Foundation of China(No.42330510,41871160,42371262)。
文摘Smart specialization is a regional development strategy that identifies regional innovation advantages through the analysis of cluster networks,while strengthening both intra-cluster and inter-cluster technological linkages to promote coordinated regional development.Drawing on branch office flow and patent cooperation data,and employing methods such as the Expectation-Maximization(EM)clustering algorithm and the‘Product Space’approach,this study investigates innovation and technological linkages both within and across industrial clusters.The key findings are as follows.First,Jiangsu’s clusters demonstrate two patterns:closely integrated industrial networks in southern cities like Suzhou,fostering strong industrial resilience,and distinct technological boundaries in northern and central cities like Yancheng,resulting in weaker integration.Second,the cluster network exhibits a single-core structure at the municipal level,centered around Nanjing,with a multi-tiered hierarchy at the district level.Third,innovation linkages between clusters follow a dual-core structure,with Nanjing and Suzhou as central hubs.In this structure,large enterprises in Nanjing and small and medium-sized enterprises(SMEs)in Suzhou reflect complementary industrial characteristics.Finally,both technology-intensive and low-tech manufacturing industries show a higher propensity for cross-regional innovation,with some cities demonstrating significant advantages in high-tech industries.Grounded in the framework of smart specialization,this study conducts an in-depth analysis of innovation and technological linkages within cluster networks at the industrial level,offering scientific insights to support the localized implementation of smart specialization strategies in the Chinese context.
