建立了碱辅助微波解聚-高效液相色谱测定灰尘中聚对苯二甲酸乙二醇酯(PET)微塑料含量的方法,并初步评估了安徽省某城市地铁站灰尘中的PET微塑料暴露水平及其影响因素。PET微塑料在含有1.0 g KOH的20 mL正戊醇溶液中,90℃微波解聚70 min...建立了碱辅助微波解聚-高效液相色谱测定灰尘中聚对苯二甲酸乙二醇酯(PET)微塑料含量的方法,并初步评估了安徽省某城市地铁站灰尘中的PET微塑料暴露水平及其影响因素。PET微塑料在含有1.0 g KOH的20 mL正戊醇溶液中,90℃微波解聚70 min,得到解聚产物对苯二甲酸。在0.5~100μg/mL浓度范围内,对苯二甲酸浓度与峰面积呈良好的线性关系(r=0.9999),检出限和定量限分别为0.17μg/mL和0.57μg/mL。地铁站灰尘中PET微塑料的浓度范围为8.24~79.42 mg/g,并且站内灰尘浓度显著高于站外(P<0.05)。统计分析结果显示,乘客流量与站内灰尘中PET微塑料含量呈显著正相关(r=0.51,P<0.05)。本方法适用于环境中PET微塑料的常规监测,为微塑料的暴露评估提供了有效的分析方法。展开更多
Emodin(1, 3, 8-trihydroxy-6-methylanthraquinone) is a derived anthraquinone compound extracted from roots and barks of pharmaceutical plants, including Rheum palmatum, Aloe vera, Giant knotweed, Polygonum multiflorum ...Emodin(1, 3, 8-trihydroxy-6-methylanthraquinone) is a derived anthraquinone compound extracted from roots and barks of pharmaceutical plants, including Rheum palmatum, Aloe vera, Giant knotweed, Polygonum multiflorum and Polygonum cuspidatum. The review aims to provide a scientific summary of emodin in pharmacological activities and toxicity in order to identify the therapeutic potential for its use in human specific organs as a new medicine. Based on the fundamental properties, such as anticancer, anti-inflammatory, antioxidant, antibacterial, antivirs, anti-diabetes, immunosuppressive and osteogenesis promotion, emodin is expected to become an effective preventive and therapeutic drug of cancer, myocardial infarction, atherosclerosis, diabetes, acute pancreatitis, asthma, periodontitis, fatty livers and neurodegenerative diseases. This article intends to provide a novel insight for further development of emodin, hoping to reveal the potential of emodin and necessity of further studies in this field.展开更多
基金the National Natural Science Foundation of China(Nos.31370992,3167040349,31670951,3197100408)the Project of the Science and Technology Department in Sichuan Province(No.2017JY0228)。
文摘Emodin(1, 3, 8-trihydroxy-6-methylanthraquinone) is a derived anthraquinone compound extracted from roots and barks of pharmaceutical plants, including Rheum palmatum, Aloe vera, Giant knotweed, Polygonum multiflorum and Polygonum cuspidatum. The review aims to provide a scientific summary of emodin in pharmacological activities and toxicity in order to identify the therapeutic potential for its use in human specific organs as a new medicine. Based on the fundamental properties, such as anticancer, anti-inflammatory, antioxidant, antibacterial, antivirs, anti-diabetes, immunosuppressive and osteogenesis promotion, emodin is expected to become an effective preventive and therapeutic drug of cancer, myocardial infarction, atherosclerosis, diabetes, acute pancreatitis, asthma, periodontitis, fatty livers and neurodegenerative diseases. This article intends to provide a novel insight for further development of emodin, hoping to reveal the potential of emodin and necessity of further studies in this field.
