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大蒜提取液对大肠埃希氏菌致家兔子宫内膜炎治疗试验
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作者 李生平 吕琛 +4 位作者 崔爱利 汪玥 朱栋栋 张勇 赵兴绪 《动物医学进展》 北大核心 2025年第7期52-57,共6页
为探索大蒜提取液对大肠埃希氏菌引起的家兔子宫内膜炎的治疗效果,从子宫内膜炎奶牛子宫脓液中分离鉴定出大肠埃希氏菌,采用榨汁法制备大蒜提取液,二倍稀释法制成各浓度药液(100%、50%、25%、12.5%、6.25%、3.13%、1.57%),用纸片扩散法... 为探索大蒜提取液对大肠埃希氏菌引起的家兔子宫内膜炎的治疗效果,从子宫内膜炎奶牛子宫脓液中分离鉴定出大肠埃希氏菌,采用榨汁法制备大蒜提取液,二倍稀释法制成各浓度药液(100%、50%、25%、12.5%、6.25%、3.13%、1.57%),用纸片扩散法筛选大蒜提取液对大肠埃希氏菌的最适抑菌浓度。结果显示,最适抑菌浓度为50%,抑菌圈直径为20.91 mm。家兔模型组子宫内膜上皮细胞脱落,结构不完整,并伴有充血,家兔血液中白细胞数增加,ELISA检测到模型组家兔子宫组织中IL-1β、IL-6、TNF-α等的浓度极显著上升(P<0.01),治疗组家兔子宫组织中IL-1β、IL-6、TNF-α等的浓度显著下降(P<0.01)。RT-qPCR检测到模型组家兔子宫组织中IL-1β、IL-6、TNF-α等的mRNA相对表达量极显著上升(P<0.01)。治疗组家兔子宫组织中IL-1β的mRNA相对表达量显著下降(P<0.05),TNF-α的mRNA相对表达量极显著下降(P<0.01),IL-6的mRNA相对表达量下降(P>0.05)。因此,大蒜提取液可能通过降低IL-1β、IL-6、TNF-α等促炎因子的相对表达量对家兔子宫内膜炎产生消炎作用。 展开更多
关键词 大蒜提取液 家兔 子宫内膜炎 白细胞介素-1Β 白细胞介素-6 肿瘤坏死因子-Α
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eMatrix水滴点阵激光联合透明质酸修护敷料治疗腹部妊娠纹 被引量:9
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作者 崔艾丽 金哲虎 《中国美容医学》 CAS 2019年第3期64-66,共3页
目的:观察eMatrix水滴点阵激光联合透明质酸修护敷料治疗腹部妊娠纹临床疗效。方法:30例腹部妊娠纹就医者随机分为治疗组和对照组,每组各15例。治疗组采用eMatrix水滴点阵激光后外用透明质酸修护敷料,2次/d,共使用7d;对照组使用eMatrix... 目的:观察eMatrix水滴点阵激光联合透明质酸修护敷料治疗腹部妊娠纹临床疗效。方法:30例腹部妊娠纹就医者随机分为治疗组和对照组,每组各15例。治疗组采用eMatrix水滴点阵激光后外用透明质酸修护敷料,2次/d,共使用7d;对照组使用eMatrix水滴点阵激光治疗。治疗结束后观察创面愈合时间,炎症后色沉的恢复情况。3个月后进行第2次治疗,共治疗3个疗程。结果:最后一次治疗结束后3个月观察评估就医者妊娠纹恢复情况。其中治疗组中9例显效,3例有效,3例无效,只有2例出现色素沉着,总有效率为80%;对照组5例显效,4例有效,6例无效,有8例出现了色素沉着,总有效率为60%,治疗组有效率显著高于对照组(P<0.05)。两组就医者均未见瘢痕、皮肤感染等并发症。结论:eMatrix水滴点阵激光联合透明质酸敷料能更好治疗妊娠纹并减少色素沉着的发生。 展开更多
关键词 eMatrix水滴点阵激光 妊娠纹 透明质酸修护敷料 联合治疗 疗效
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Studies on the Lanthanum-Modified Lead Titanate Ultrafine Particles by Raman Spectroscopy 被引量:1
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作者 cui ai-li GE Xu-dong +2 位作者 HU Yong-qi JIN Yong WANG Xiao-hui 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 1998年第2期76-79,共4页
Lanthanummodified lead titanate(PLT14) ultrafine particles were synthesized by means of stearic acid gel method. The structure of the samples was characterized using Xray diffraction(XRD) and TEM. The crystal graphic ... Lanthanummodified lead titanate(PLT14) ultrafine particles were synthesized by means of stearic acid gel method. The structure of the samples was characterized using Xray diffraction(XRD) and TEM. The crystal graphic parameters of the samples were calculated. The Raman spectra of PLT14 powders at a high pressure as well as a high temperature reveal that the phase transition pressure or temperature shifts to a lower pressure or temperature with the decrease of grain size. 展开更多
关键词 Raman spectrum PLT Ultrafine particle Size effect
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Human bocavirus in children suffering from acute lower respiratory tract infection in Beijing Children's Hospital 被引量:7
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作者 ZHANG Li-li TANG Liu-ying +8 位作者 XIE Zheng-de TAN Xiao-juan LI Chong-shan cui ai-li JI Yi-xin XU Song-tao MAO Nai-ying XU Wen-bo SHEN Kun-ling 《Chinese Medical Journal》 SCIE CAS CSCD 2008年第17期1607-1610,共4页
Background Human bocavirus (HBoV) is a parvovirus recently found to possibly cause respiratory tract disease in children and adults. This study investigated HBoV infection and its clinical characteristics in childre... Background Human bocavirus (HBoV) is a parvovirus recently found to possibly cause respiratory tract disease in children and adults. This study investigated HBoV infection and its clinical characteristics in children younger than five years of age suffering from acute lower respiratory tract infection in Beijing Children's Hospital. Methods Nasopharyngeal aspirates were collected from children suffering from acute lower respiratory tract infection during the winters of 2004 to 2006 (from November through the following February). HBoV was detected by polymerase chain reaction amplification and virus isolation and the amplification products were sequenced for identification. Results HBoV infection was detected in 16 of 333 study subjects. Coinfections with respiratory syncytial virus were detected in 3 of 16 HBoV positive patients with acute lower respiratory tract infection. The median age for HBoV positive children was 8 months (mean age, 17 months; range, 3 to 57 months). Among the HBoV positive children, 14 were younger than 3 years old, 9 were younger than 1 year old and 7 were younger than 6 months. These 16 positive HBoV children exhibited coughing and abnormal chest radiography findings and more than 60% of these children had wheezing and fever. Ten children were clinically diagnosed with pneumonia, 2 bronchiolitis, 2 acute bronchitis and 2 asthma. One child died. Conclusions HBoV was detected in about 5% of children with acute lower respiratory infection seen in Beijing Children's HosPital. Further investigations regarding clinical and epidemiologic characteristics of HBoV infection are needed. 展开更多
关键词 BOCAVIRUS CHILD respiratory tract infections polymerase chain reaction
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溃疡性结肠炎患者肠道菌群及体液免疫变化的临床意义 被引量:3
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作者 崔爱丽 庞世超 于莹莹 《中国肛肠病杂志》 2021年第4期28-30,共3页
为探讨溃疡性结肠炎患者肠道菌群及体液免疫变化的临床意义,将溃疡性结肠炎患者60例根据患者结肠炎严重程度分为轻度组和重度组,每组30例;同期选取50名于本院体检的健康人群作为对照组,检测并比较3组肠道菌群失调情况及免疫球蛋白指标... 为探讨溃疡性结肠炎患者肠道菌群及体液免疫变化的临床意义,将溃疡性结肠炎患者60例根据患者结肠炎严重程度分为轻度组和重度组,每组30例;同期选取50名于本院体检的健康人群作为对照组,检测并比较3组肠道菌群失调情况及免疫球蛋白指标水平。结果显示,轻度组和重度组肠道菌群失调率高于对照组(P <0.05),且轻度组失调率低于重度组(P <0.05)。轻度组与重度组IgA、IgG水平高于对照组(P <0.05),IgM水平低于对照组(P <0.05);且轻度组IgA、IgG水平低于重度组(P <0.05),IgM水平高于重度组(P <0.05)。结果表明,溃疡性结肠炎患者伴有肠道菌群失调,且随着病情发展其失调症状越严重,机体IgA、IgG水平上升,IgM水平下降;临床可根据肠道菌群与体液免疫变化判断疾病严重程度,指导治疗。 展开更多
关键词 溃疡性结肠炎 肠道菌群 体液免疫
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