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A novel robust aerodynamic optimization technique coupled with adjoint solvers and polynomial chaos expansion 被引量:5
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作者 Wei ZHANG Qiang WANG +1 位作者 Fanzhi ZENG chao yan 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2022年第10期35-55,共21页
Uncertainty is common in the life cycle of an aircraft, and Robust Aerodynamic Optimization(RAO) that considers uncertainty is important in aircraft design. To avoid the curse of dimensionality in surrogate-based opti... Uncertainty is common in the life cycle of an aircraft, and Robust Aerodynamic Optimization(RAO) that considers uncertainty is important in aircraft design. To avoid the curse of dimensionality in surrogate-based optimization, this study proposes an adjoint RAO technique called “R-Opt”. Polynomial Chaos Expansion(PCE) is coupled with the R-Opt technique to quantify uncertainty in the responses of the target(including its mean and standard deviation). Only one process of PCE model construction is required in each iteration, and the gradients of uncertainty can be inferred via chain rules. The proposed method is more efficient than prevalent methods,and avoids the problem of a disagreement over the best PCE basis from among a number of PCE models(especially in case of sparse PCE). It also supports the application of sparse PCE.Two benchmark tests and two airfoil cases were used to verify R-Opt, and the optimal solutions were deemed to be robust. It improved the mean aerodynamic performance and reduced the standard deviation of the target. 展开更多
关键词 Adjoint technique Polynomial chaos expansion Robust design Uncertainty analysis Uncertainty gradient propagation
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十八碳二烯酸酯特异性脂肪酶菌株筛选鉴定及优化的研究
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作者 刘田伟 吴伟 +8 位作者 李昌珠 刘汝宽 李培旺 陈景震 肖静晶 晁燕 谭华元 陈韵竹 易有金 《中国粮油学报》 北大核心 2025年第6期109-118,共10页
为得到功能油脂的特异性产脂肪酶菌株,以油茶籽油为唯一碳源,应用罗丹明B培养基从发酵油茶饼粕中得到产脂肪酶菌株,采用p-NPP为底物测定酶活,筛选出1株高产酶菌株CoB10,经16S rDNA基因序列比对及系统发育树的构建,确定该菌株为链霉菌(St... 为得到功能油脂的特异性产脂肪酶菌株,以油茶籽油为唯一碳源,应用罗丹明B培养基从发酵油茶饼粕中得到产脂肪酶菌株,采用p-NPP为底物测定酶活,筛选出1株高产酶菌株CoB10,经16S rDNA基因序列比对及系统发育树的构建,确定该菌株为链霉菌(Streptomyces)。CoB10具备水解油茶籽油中甘油三酯的能力,经超高效液相色谱-质谱联用检测,CoB10组油茶籽油中甘油三酯含量明显下降,由439.16μg/mg降低到329.76μg/mg,CoB10可特异水解十八碳二烯酸酯。采用单因素实验及响应面法对菌株产脂肪酶活力的发酵条件进行优化,得到最优发酵条件为发酵温度37.4℃、接种质量分数2.1%、油茶籽油质量分数1.5%、初始pH 6.9,此条件下菌株产脂肪酶活力为0.460 U/mL,是优化前(0.295 U/mL)的1.56倍。 展开更多
关键词 脂肪酶 十八碳二烯酸 响应面优化 发酵条件 酶学性质
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解表清里方通过调控TLR7/MAPK/NF-κB通路对甲流病毒感染所致肺炎的防治作用
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作者 明雨 马一川 +2 位作者 姚睿祺 晁燕 张洪春 《中国实验方剂学杂志》 北大核心 2025年第11期173-181,共9页
目的:探讨解表清里方对甲型流感病毒(IAV)感染所致肺炎的药效机制。方法:将132只Balb/c小鼠随机分为空白(NC)组,模型(IAV)组,奥司他韦(OSV)组(37.5mg·kg^(-1)),解表清里方高、中、低剂量(H、M、L-JQD)组(6.05、3.02、1.51 g·k... 目的:探讨解表清里方对甲型流感病毒(IAV)感染所致肺炎的药效机制。方法:将132只Balb/c小鼠随机分为空白(NC)组,模型(IAV)组,奥司他韦(OSV)组(37.5mg·kg^(-1)),解表清里方高、中、低剂量(H、M、L-JQD)组(6.05、3.02、1.51 g·kg^(-1))。NC组给予生理盐水滴鼻,其他各组在鼻内接种A/Brisbane/02/2018(H1N1)[pdm09-like virus(H1N1)]构建流感病毒感染的动物模型。造模2 h后,NC组和IAV组给予生理盐水灌胃,其他各组给予对应药物灌胃,7 d。给药期间每日记录小鼠体质量、生存状态、死亡数量。第3、7天测量小鼠肺指数;苏木素-伊红(HE)染色观察肺组织病理形态学变化;使用实时荧光定量聚合酶链式反应(Real-time PCR)检测肺组织中病毒载量(IAV-M)、Toll样受体7(TLR7)、p38丝裂原活化蛋白激酶(p38MAPK)、核转录因子-κB(NF-κB)m RNA表达;使用蛋白免疫印迹法(Western blot)检测肺组织中p38 MAPK、NF-κB蛋白表达水平;使用酶联免疫吸附测定法(ELISA)检测血清中白细胞介素(IL)-2、IL-6、肿瘤坏死因子(TNF)-α含量。结果:与NC组比较,IAV组小鼠生存质量下降,生存天数减少(P<0.01),肺部充血、炎性细胞浸润,肺指数升高(P<0.01),病毒载量升高(P<0.01),TLR7、p38 MAPK、NF-κB表达升高(P<0.05,P<0.01),IL-2含量降低(P<0.01),IL-6、TNF-α含量升高(P<0.01)。与IAV组比较,H-JQD组小鼠生存天数延长(P<0.05);JQD三组小鼠肺组织病理改变减轻,肺指数下降(P<0.01);M、H-JQD组小鼠肺组织病毒载量减少(P<0.01)。与IAV组比较,H-JQD组小鼠TLR7、p38 MAPK、NF-κB m RNA表达降低(P<0.05,P<0.01),p38MAPK、NF-κB蛋白表达水平减少(P<0.01),血清中IL-2含量增加(P<0.01),IL-6、TNF-α含量减少(P<0.05,P<0.01);M-JQD组小鼠肺组织NF-κB m RNA表达降低(P<0.01),p38 MAPK蛋白表达水平减少(P<0.05),血清中IL-2含量增加(P<0.01),TNF-α含量减少(P<0.01)。结论:M、H-JQD剂量依赖性地下调TLR7/MAPK/NF-κB信号通路,增加IL-2,减少IL-6、TNF-α细胞因子的过度分泌,从而改善IAV感染所致的肺炎。 展开更多
关键词 解表清里方 甲型流感病毒(IAV) 流行性感冒 Toll样受体7(TLR7)/丝裂原活化蛋白激酶(MAPK)/核转录因子-κB(NF-κB)信号通路 细胞因子
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基于单细胞转录组测序分析构建花斑裸鲤三种造血器官细胞图谱
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作者 寇若彬 刘丹 +8 位作者 高强 晁燕 张存芳 聂苗苗 贾军梅 谭瑾 郭守全 姚占雯 祁得林 《动物学杂志》 北大核心 2025年第1期69-79,共11页
利用单细胞转录组测序技术在细胞水平探究花斑裸鲤(Gymnocypris eckloni)肾、肝和脾三种造血器官中的细胞组成类型,系统描绘花斑裸鲤这三种造血器官的细胞图谱,为进一步研究花斑裸鲤造血系统发育,尤其是红细胞发育积累科学数据。研究方... 利用单细胞转录组测序技术在细胞水平探究花斑裸鲤(Gymnocypris eckloni)肾、肝和脾三种造血器官中的细胞组成类型,系统描绘花斑裸鲤这三种造血器官的细胞图谱,为进一步研究花斑裸鲤造血系统发育,尤其是红细胞发育积累科学数据。研究方法包括花斑裸鲤肾、肝和脾三种造血器官的单细胞悬液制备、单细胞RNA-seq文库构建、测序以及降维聚类分析、细胞注释、差异基因分析和功能富集分析。结果表明,花斑裸鲤三种造血器官内存在类型丰富的细胞,包括红细胞、中性粒细胞、T细胞、B细胞、树突状细胞、上皮细胞、巨噬细胞、血管内皮细胞、肌细胞、成纤维细胞、单核细胞和神经细胞。在三种器官中细胞分布存在较大的异质性:脾中参与发挥红细胞功能的细胞群分布占比较大;肾中参与免疫反应的细胞群分布占比较大;肝中血管内皮细胞和肌细胞分布占比较大。在功能方面,花斑裸鲤与多数硬骨鱼类相似,它的肾、脾和肝不仅参与造血及红细胞的发育,而且对于免疫系统的发育和应答等过程也发挥一定作用。本研究从单细胞角度对花斑裸鲤造血系统发育研究进行了一定的补充与完善,展现了三种造血器官中细胞分布的特征与差异,对于后续进一步预测花斑裸鲤的红细胞发育路径提供了一定的研究基础。 展开更多
关键词 单细胞转录组测序 造血系统发育 细胞图谱 花斑裸鲤
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探讨梅花针对内斜视术后儿童多焦视觉诱发电位的影响与疗效评估 被引量:1
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作者 付燕梅 巢艳 +1 位作者 林川 胡扬涛 《中国中医眼科杂志》 2025年第7期619-625,共7页
目的 探讨梅花针对内斜视术后儿童多焦视觉诱发电位(mVEP)的影响,为内斜术后的疗效评估提供新的依据。方法 纳入2022年7月—2024年7月南昌市第九〇八医院眼科住院手术的交替性内斜视患儿80例(160只眼),随机分为对照组和治疗组各40例(80... 目的 探讨梅花针对内斜视术后儿童多焦视觉诱发电位(mVEP)的影响,为内斜术后的疗效评估提供新的依据。方法 纳入2022年7月—2024年7月南昌市第九〇八医院眼科住院手术的交替性内斜视患儿80例(160只眼),随机分为对照组和治疗组各40例(80只眼)。对照组给予常规手术治疗,治疗组在术前进行一个疗程梅花针治疗后再进行内斜视手术。分别于2组患者术前和术后1、3、6个月检测视网膜mVEP并进行比较。结果 (1)6个离心度视网膜mVEP振幅反应密度及潜伏期:治疗组术后3、6个月第一、二环的视网膜mVEP振幅反应密度均较术前提高,差异均有统计学意义(P<0.05)。2组间比较,治疗组术后3、6个月第一、二环的视网膜mVEP振幅反应密度均高于对照组,差异均有统计学意义(P<0.05)。2组术后各时间点6个离心度的视网膜mVEP潜伏期与术前比较,及术后各时间点2组间比较,差异均无统计学意义(P>0.05)。(2)鼻、颞侧视网膜mVEP的振幅反应密度及潜伏期:治疗组术后3、6个月鼻、颞侧视网膜mVEP的振幅反应密度均较术前提高,差异均有统计学意义(P<0.05)。2组间比较,治疗组术后3、6个月鼻、颞侧视网膜mVEP的振幅反应密度均高于对照组(P<0.05)。2组术后各时间点鼻、颞侧视网膜mVEP的潜伏期与术前比较及术后各时间点2组间比较,差异均无统计学意义(P>0.05)。(3)上、下半侧视网膜mVEP的振幅反应密度及潜伏期:治疗组术后3、6个月上、下半侧视网膜mVEP的振幅反应密度均较术前提高,差异均有统计学意义(P<0.05)。2组间比较,术后3、6个月治疗组上、下半侧视网膜mVEP的振幅反应密度均高于对照组,差异均有统计学意义(P<0.05)。2组术后各时间点上、下半侧视网膜mVEP的潜伏期与术前比较及术后各时间点2组间比较,差异均无统计学意义(P>0.05)。(4)眼位情况:术后1个月2组患者均可以保持正位,术后6个月治疗组眼正位例数(39例)高于对照组(30例),差异有统计学意义(χ^(2)=8.537,P=0.003)。结论 内斜视患者术后视觉传导通路均有不同程度的恢复,术后联合梅花针治疗视觉传导通路有明显提高。 展开更多
关键词 多焦视觉诱发电位 梅花针 内斜视
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负压封闭引流技术联合可调式皮肤牵开器治疗胫骨开放性骨折后骨外露的疗效研究 被引量:15
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作者 严超 尚峥辉 +4 位作者 陈剑锋 伍伟飞 陈波 张坤 张帆 《中国现代医学杂志》 CAS 2019年第4期123-126,共4页
目的探讨负压封闭引流(VSD技术)联合可调式皮肤牵开器治疗创伤后胫骨骨外露的效果。方法 22例胫骨开放性骨折后较大面积胫骨外露患者先行清创及VSD,连续3次细菌培养阴性。创面清洁后应用可调式皮肤牵开器逐步牵拉方法覆盖骨外露创面,待... 目的探讨负压封闭引流(VSD技术)联合可调式皮肤牵开器治疗创伤后胫骨骨外露的效果。方法 22例胫骨开放性骨折后较大面积胫骨外露患者先行清创及VSD,连续3次细菌培养阴性。创面清洁后应用可调式皮肤牵开器逐步牵拉方法覆盖骨外露创面,待皮缘靠拢后行清创缝合。结果 22例患者中皮缘靠拢清创缝合后19例胫骨外露创面14 d后拆线,愈合良好;2例患者出现伤口渗液,经换药后伤口闭合;1例患者最终出现感染性窦道渗液出院。所有患者获随访,随访时间6~8个月,平均6.5个月。结论 VSD贯序可调式皮肤牵开器牵张治疗胫骨骨外露可避免皮瓣手术的痛苦,减小手术创伤,治疗效果良好。 展开更多
关键词 胫骨骨折 引流术 骨折愈合 治疗结果
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Inconsistent capacity of potential HONO sources to enhance secondary pollutants:Evidence from WRF-Chem modeling
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作者 Jingwei Zhang Haiyan Ran +13 位作者 Yu Qu chaofan Lian Weigang Wang Yusheng Zhang Feixue Zheng Xiaolong Fan Dawei Lu chao yan Kaspar RDaellenbach Zhiqiang Ma Yongchun Liu Maofa Ge Markku Kulmala Junling An 《Journal of Environmental Sciences》 2025年第12期812-830,共19页
Nitrous acid(HONO)is a crucial source of OH radicals in the troposphere,significantly enhancing secondary pollutants like secondary organic aerosols(SOA)and peroxyacetyl nitrates(PAN).While prior research has examined... Nitrous acid(HONO)is a crucial source of OH radicals in the troposphere,significantly enhancing secondary pollutants like secondary organic aerosols(SOA)and peroxyacetyl nitrates(PAN).While prior research has examined HONO sources and their total impacts on secondary pollution,the specific enhancement capacity of each individual HONO source remains underexplored.This study uses observational data from 2015 to 2018 for HONO,SOA,and PAN across six sites in China,combined with WRF-Chem model adding six potential HONO sources to evaluate their capacity:traffic emissions(E_traffic),soil emissions(E_soil),indoor-outdoor exchange(E_indoor),nitrate photolysis(P_nit),and NO_(2) heterogeneous reactions on aerosol and ground surfaces(Het_a,Het_g).The simulated HONO contributions near the ground in urban Beijing were:12%from NO+OH(default source),10%-20%from E_traffic,1%-12%from P_nit,2%-10%from Het_a,and 50%-70% from Het_g.For SOA and PAN,we calculated incremental contributions enhanced by each HONO source and derived enhancement ratios(ERs)normalized against HONO’s contribution:~7 for P_nit,~2 for Het_a,~0.9 for Het_g,~0.8 for E_soil,~0.3 for E_traffic,and~0.1 for E_indoor.HONO sources’capacity to enhance secondary pollutants varies,being larger for aerosol-related sources.Vertical analysis on HONO concentration,spatial distribution,RO_(x) radical cycling rates,and OH enhancements revealed that aerosol-related HONO sources,especially P_nit,contribute more to secondary pollution.Future research should focus more on assessing real-world impacts of HONO sources,besides identifying their budgets.Additionally,uptake coefficient(γ)and nitrate photolysis frequency(J_(nitrate))critically affect HONO and secondary pollutant formation,necessitating further investigations. 展开更多
关键词 Nitrous acid WRF-Chem Secondary organic aerosols Peroxyacetyl nitrate Atmospheric oxidation capacity Vertical profiles
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Dynamic evolution of the NDVI and driving factors in the Mu Us Sandy Land of China from 2002 to 2021
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作者 chao yan ZHU Yonghua +2 位作者 WANG Xiaohan LI Jiamin LIANG Li'e 《Journal of Arid Land》 2025年第5期605-623,共19页
Investigating the spatiotemporal evolution of vegetation and its response mechanisms to natural and anthropogenic elements is crucial for regional vegetation restoration and ecological preservation.The Mu Us Sandy Lan... Investigating the spatiotemporal evolution of vegetation and its response mechanisms to natural and anthropogenic elements is crucial for regional vegetation restoration and ecological preservation.The Mu Us Sandy Land(MUSL),which is situated in the semi-arid zone of northwestern China adjacent to the Loess Plateau,has been at the forefront of desertification and oasis formation over the past two millennia.This study is based on the synthesis of the Normalized Difference Vegetation Index(NDVI)data from MOD13A3 data in the MODIS(Moderate-Resolution Imaging Spectroradiometer)dataset(2002-2021)and climate data(temperature and precipitation)at annual and monthly scales from the National Earth System Science Data Center.A range of analytical methods,including univariate linear regression,Theil-Sen trend analysis and Mann-Kendall significance test,correlation analysis,residual analysis,and Hurst index,were used to explore the response mechanisms of the NDVI to climate change and human activities and to predict the future trends of the NDVI in the MUSL.The results showed that through the method of correlation analysis,in terms of both spatially averaged correlation coefficients and area proportion,the NDVI was positively correlated with temperature and precipitation in 97.59%and 96.51%of the study area,respectively,indicating that temperature has a greater impact on the NDVI than precipitation.Residual analysis quantified the contributions of climate change and human activities to the NDVI changes,revealing that climate change and human activities contribute up to 30.00%and 70.00%,respectively,suggesting that human activities predominantly affect the NDVI changes in the MUSL.The Hurst index was used to categorize the future trend of the NDVI into four main directions of development:continuous degradation(0.05%of the study area),degradation in the past but improvement in the future(54.45%),improvement in the past but degradation in the future(0.13%),and continuous improvement(45.36%).In more than 50.00%of the regions that have been degraded in the past but were expected to improve in the future,the NDVI was expected to exhibit a stable trend of anti-persistent improvement.These findings provide theoretical support for future ecological protection,planning,and the implementation of ecological engineering in the MUSL,and also offer a theoretical basis for the planning and execution of construction projects,environmental protection measures,and the sustainable development of vegetation. 展开更多
关键词 Normalized Difference Vegetation Index(NDVI) climate change human activities residual analysis Hurst index Mu Us Sandy Land
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A production term correction for Menter shear-stress transport turbulence model for adverse pressure gradient flows before separation
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作者 Hanqi SONG Mingze MA +2 位作者 Jinrong ZHANG Yifan LI chao yan 《Chinese Journal of Aeronautics》 2025年第5期28-38,共11页
To address the early separation problem in the Menter Shear-Stress Transport(SST)turbulence model,a correction for the Turbulent Kinetic Energy(TKE)production term,P_(k),is introduced to account for the effect of the ... To address the early separation problem in the Menter Shear-Stress Transport(SST)turbulence model,a correction for the Turbulent Kinetic Energy(TKE)production term,P_(k),is introduced to account for the effect of the Adverse Pressure Gradient(APG).The correction is determined based on the distribution of Pkin the APG region before separation.When the friction coefficient C_(f) is decomposed,its direct dependence on Pkis clearly observed.However,with the introduction of Bradshaw’s assumption,Pkin the SST turbulence model is over-suppressed,resulting in a lower inner peak or no significant inner peak distribution at all.To address this problem,this paper proposes a Gaussian function,HGauss,which corrects the numerical values of P_(k) involved in the calculation of the Menter SST model by focusing on the inner peak region of P_(k).The modified SST model is then applied to four cases with APGs.The modification leads to an increase in the wall friction coefficient C_(f)in the APG region and causes a downstream shift in the separation location,improving the model’s consistency with high-accuracy data and experimental results.It is demonstrated that this correction can improve the early separation problem in the Menter SST turbulence model. 展开更多
关键词 Early separation problem Adverse pressuregradient Turbulencemodels Productionterm Gaussian function Boundary layer flow
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Dual-Branch Gaze Estimation Algorithm with Gaussian Mixture Distribution Heatmaps and Dynamic Adaptive Loss Function
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作者 Songyin Dai chaoran Zhang +2 位作者 Cheng Xu chao yan Jie Huang 《Journal of Beijing Institute of Technology》 2025年第5期433-446,共14页
Gaze estimation,a crucial non-verbal communication cue,has achieved remarkable progress through convolutional neural networks.However,accurate gaze prediction in uncon-strained environments,particularly in extreme hea... Gaze estimation,a crucial non-verbal communication cue,has achieved remarkable progress through convolutional neural networks.However,accurate gaze prediction in uncon-strained environments,particularly in extreme head poses,partial occlusions,and abnormal lighting,remains challenging.Existing models often struggle to effectively focus on discriminative ocular features,leading to suboptimal performance.To address these limitations,this paper proposes dual-branch gaze estimation with Gaussian mixture distribution heatmaps and dynamic adaptive loss function(DMGDL),a novel dual-branch gaze estimation algorithm.By introducing Gaussian mixture distribution heatmaps centered on pupil positions as spatial attention guides,the model is enabled to prioritize ocular regions.Additionally,a dual-branch network architecture is designed to separately extract features for yaw and pitch angles,enhancing flexibility and mitigating cross-angle interference.A dynamic adaptive loss function is further formulated to address discontinuities in angle estimation,improving robustness and convergence stability.Experimental evaluations on three benchmark datasets demonstrate that DMGDL outperforms state-of-the-art methods,achiev-ing a mean angular error of 3.98°on the Max-Planck institute for informatics face gaze(MPI-IFaceGaze)dataset,10.21°on the physically unconstrained gaze estimation in the wild(Gaze360)dataset and 6.14°on the real-time eye gaze estimation in natural environments(RT-Gene)dataset,exhibiting superior generalization and robustness. 展开更多
关键词 gaze estimation Gaussian mixture distribution heatmaps dynamic adaptive loss func-tion attention mechanism dual-branch network
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Novel adaptive IMEX two-step Runge-Kutta temporal discretization methods for unsteady flows
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作者 Xueyu QIN Jian YU +2 位作者 Xin ZHANG Zhenhua JIANG chao yan 《Chinese Journal of Aeronautics》 2025年第8期142-153,共12页
Efficient and accurate simulation of unsteady flow presents a significant challenge that needs to be overcome in computational fluid dynamics.Temporal discretization method plays a crucial role in the simulation of un... Efficient and accurate simulation of unsteady flow presents a significant challenge that needs to be overcome in computational fluid dynamics.Temporal discretization method plays a crucial role in the simulation of unsteady flows.To enhance computational efficiency,we propose the Implicit-Explicit Two-Step Runge-Kutta(IMEX-TSRK)time-stepping discretization methods for unsteady flows,and develop a novel adaptive algorithm that correctly partitions spatial regions to apply implicit or explicit methods.The novel adaptive IMEX-TSRK schemes effectively handle the numerical stiffness of the small grid size and improve computational efficiency.Compared to implicit and explicit Runge-Kutta(RK)schemes,the IMEX-TSRK methods achieve the same order of accuracy with fewer first derivative calculations.Numerical case tests demonstrate that the IMEX-TSRK methods maintain numerical stability while enhancing computational efficiency.Specifically,in high Reynolds number flows,the computational efficiency of the IMEX-TSRK methods surpasses that of explicit RK schemes by more than one order of magnitude,and that of implicit RK schemes several times over. 展开更多
关键词 Implicit-explicit temporal methods Two-step Runge-Kutta methods Adaptive algorithm Unsteady flows Navier-Stokes equations
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Correction:Positron annihilation study of defect formation and evolution in matrix graphite under He ion irradiation
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作者 Hong-Xia Xu Jian-Dang Liu +8 位作者 Bang-Jiao Ye Zi-Wen Pan Jun Lin Jin-Liang Song Jian-Qing Cao chao yan Ying-Ping Hao Jin-Xing Cheng Qing-Bo Wang 《Nuclear Science and Techniques》 2025年第6期241-241,共1页
Correction:Nuclear Science and Techniques(2025)36:4 https://doi.org/10.1007/s41365-024-01548-5 In this article,the caption for Fig(s)1,3,and 4 was inadvert-ently truncated.The incorrect and the corrected captions are ... Correction:Nuclear Science and Techniques(2025)36:4 https://doi.org/10.1007/s41365-024-01548-5 In this article,the caption for Fig(s)1,3,and 4 was inadvert-ently truncated.The incorrect and the corrected captions are given below. 展开更多
关键词 defect formation EVOLUTION He ion irradiation positron annihilation matrix graphite
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Noncovalently functionalized organic graphene aerogel composite for high-performance proton storage
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作者 Jing He Maoding Cheng +3 位作者 Qinglong Jiang Subramania Angaiah Minjie Shi chao yan 《Chinese Journal of Chemical Engineering》 2025年第3期260-268,共9页
Although organic compounds are considered to be promising electrode materials with their remarkable characteristics such as diverse structures,design controllability,and environmental friendliness,their low charge-tra... Although organic compounds are considered to be promising electrode materials with their remarkable characteristics such as diverse structures,design controllability,and environmental friendliness,their low charge-transfer capability and limited cycling durability hinder their application in aqueous proton batteries.Herein,we prepared a noncovalent phenazine-based graphene aerogel(H/G)composite for aqueous proton storage,which is realized by redox-active Hexaazatrinaphthalene(HATN)organic compound combined with conductive reduced graphene oxide(rGO).The integration of rGO into HATN not only effectively optimizes the electronic structure of the H/G composite to enhance its electrochemical activity,but also the favorable noncovalent π-π interaction existed between HATN and rGO provides a stable structure for fast electron transportation.The obvious electron transfer in the aerogel composite promotes fast and reversible redox reactions occurred with the imino-active HATN in the composite electrode for proton uptake/removal in an aqueous acidic electrolyte,which are demonstrated by in-situ Fourier transform infrared(FTIR)investigation,theoretical calculations and experimental measurements.Therefore,it can deliver a fast,stable and efficient aqueous proton storage behavior with a large specific capacity of 274 mA·h·g^(-1) and considerable calendar life with~100%capacity retention after 3000 cycles,surpassing previously reported proton-based organic electrodes in aqueous acidic electrolytes.Furthermore,an outstanding soft-package aqueous proton(APB)has been fabricated with considerable long-term cycling stability. 展开更多
关键词 Organic compounds Composite materials Noncovalent interactions Energy storage Aqueous proton batteries
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江西省2023年高考军招体检人员近视患病率及不同屈光手术相关分析
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作者 林川 臧鹰 +3 位作者 巢艳 付燕梅 戴玉凤 罗娟 《中国医药指南》 2025年第20期127-129,共3页
目的分析江西省高考军招体检的毕业生近视患病率及行屈光手术的疗效,为近视防控工作、干预手段疗效提供数据支持。方法本研究为横断面研究,以普查的方式对2023年6月27日至2023年6月30日参加江西省高考军招体检项目的毕业生进行调查。对... 目的分析江西省高考军招体检的毕业生近视患病率及行屈光手术的疗效,为近视防控工作、干预手段疗效提供数据支持。方法本研究为横断面研究,以普查的方式对2023年6月27日至2023年6月30日参加江西省高考军招体检项目的毕业生进行调查。对所有受试者采用军检规范化检查,对结果进行全面、综合分析。结果纳入2023年江西省参加军检的高考毕业生共1788人,其中近视1502人,近视患病率84.00%。近视人群中,行屈光手术治疗758人次,手术日期距体检日期超过半年者428人次。其中飞秒激光小切口角膜基质透镜切除术(SMILE)250人,飞秒激光辅助的准分子激光原位角膜磨镶术手术(FS-LASIK)155人,表层激光手术(T-PRK)5人,晶状体眼后房型人工晶状体植入术(ICL)0人。结论建议采用预防措施降低江西省高中生近视患病率,针对屈光手术术后并发症,加强术后复查等健康教育和及时的医疗干预。 展开更多
关键词 近视 体检 视力 屈光手术 并发症
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Positron annihilation study of defect formation and evolution in matrix graphite under He ion irradiation
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作者 Hong-Xia Xu Jian-Dang Liu +8 位作者 Bang-Jiao Ye Zi-Wen Pan Jun Lin Jin-Liang Song Jian-Qing Cao chao yan Ying-Ping Hao Jin-Xing Cheng Qing-Bo Wang 《Nuclear Science and Techniques》 2025年第1期13-21,共9页
The stability of matrix graphite under neutron irradiation and in corrosive environments is crucial for the safe operation of molten salt reactors(MSRs).Raman spectroscopy and a slow positron beam were employed to inv... The stability of matrix graphite under neutron irradiation and in corrosive environments is crucial for the safe operation of molten salt reactors(MSRs).Raman spectroscopy and a slow positron beam were employed to investigate the effects of He ion irradiation fluences and subsequent annealing on the microstructure and defects of the matrix graphite.He ions with 500 keV energy and fluences ranging from 1.1×10^(15)ions∕cm^(2)to 3.5×10^(17)ions∕cm^(2)were used to simulate neutron irradiation at 300 K.The samples with an irradiation fluence of 3.5×10^(16)ions∕cm^(2)were subjected to isochronal annealing at different temperatures(573 K,873 K and 1173 K)for 3 h.The Raman results revealed that the D peak gradually increased,whereas the intrinsic G peak decreased with increasing irradiation fluence.At the same irradiation fluence,the D peak gradually decreased,whereas the intrinsic G peak increased with increasing annealing temperature.Slow positron beam analysis demonstrated that the density or size of irradiation defects(vacancy type)increased with higher irradiation fluence,but decreased rapidly with increasing annealing temperature.The Raman spectral analysis of sample cross sections subjected to high irradiation fluences revealed the emergence of amorphization precisely at the depth where ion damage was most pronounced,whereas the surface retained its crystalline structure.Raman and positron annihilation analyses indicated that the matrix graphite exhibited good irradiation resistance to He ions at 300 K.However,vacancy-type defects induced by He ion irradiation exhibit poor thermal stability and can be easily removed during annealing. 展开更多
关键词 GRAPHITE Positron annihilation IRRADIATION Raman spectrum
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Near-infrared optical imaging for intraoperative identi-cation and assessment of parathyroid glands
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作者 Jie Kang Ziyang Ye +1 位作者 chao yan Bobo Gu 《Journal of Innovative Optical Health Sciences》 2025年第5期17-31,共15页
Accurate identification and viability assessment of the parathyroid glands(PGs)are critical when performing thyroid and parathyroid surgeries.Traditional visual inspection-based intrao-perative methods suffer from sub... Accurate identification and viability assessment of the parathyroid glands(PGs)are critical when performing thyroid and parathyroid surgeries.Traditional visual inspection-based intrao-perative methods suffer from subjectivity and uncertainty.Near-infrared(NIR)imaging meth-ods,including NIR autofluorescence(NIRAF)imaging and indocyanine green fluorescence imaging(ICGFI),have emerged as promising and reliable techniques for intraoperative PG identification and assessment.Here,the principles and clinical performanoe of NIR imaging methods were comprehensively reviewed. 展开更多
关键词 Parathyroid glands NEAR-INFRARED AUTOFLUORESCENCE indocyanine green.
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Efficient implementation of the k-√k L turbulence model with the discontinuous Galerkin method
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作者 Zhenhua Jiang chao yan +1 位作者 Jian Yu Yao Li 《Acta Mechanica Sinica》 2025年第4期70-81,共12页
We present the approaches to implementing the k-√k L turbulence model within the framework of the high-order discontinuous Galerkin(DG)method.We use the DG discretization to solve the full Reynolds-averaged Navier-St... We present the approaches to implementing the k-√k L turbulence model within the framework of the high-order discontinuous Galerkin(DG)method.We use the DG discretization to solve the full Reynolds-averaged Navier-Stokes equations.In order to enhance the robustness of approaches,some effective techniques are designed.The HWENO(Hermite weighted essentially non-oscillatory)limiting strategy is adopted for stabilizing the turbulence model variable k.Modifications have been made to the model equation itself by using the auxiliary variable that is always positive.The 2nd-order derivatives of velocities required in computing the von Karman length scale are evaluated in a way to maintain the compactness of DG methods.Numerical results demonstrate that the approaches have achieved the desirable accuracy for both steady and unsteady turbulent simulations. 展开更多
关键词 Discontinuous Galerkin method k-√k L turbulence model High-order scheme
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尾叶桉GLU4无性系F5H基因的克隆表达及序列分析 被引量:2
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作者 肖玉菲 刘海龙 +2 位作者 刘雄盛 晏巢 陈博雯 《生物技术》 CAS 2018年第3期205-211,共7页
[目的]克隆尾叶桉(Eucalyptus urophylla)GLU4中F5H基因全长,并对其进行序列和表达模式分析。[方法]根据NCBI公布的F5H基因保守序列设计引物,以尾叶桉GLU4茎部组织为试验材料克隆其g DNA和c DNA片段,利用荧光定量PCR分析其在植株不同组... [目的]克隆尾叶桉(Eucalyptus urophylla)GLU4中F5H基因全长,并对其进行序列和表达模式分析。[方法]根据NCBI公布的F5H基因保守序列设计引物,以尾叶桉GLU4茎部组织为试验材料克隆其g DNA和c DNA片段,利用荧光定量PCR分析其在植株不同组织中的表达模式。[结果]该基因g DNA长2 358 bp,c DNA长1 610 bp,含有2个外显子、1个内含子。开放阅读框编码529个氨基酸,Eu F5H编码的蛋白为一个带负电荷、存在跨膜结构、定位在内质网起始分泌途径中的蛋白质,二级结构包含典型的的α-螺旋和β-折叠,根据三级结构推测其可能具有羟化酶活性。Eu F5H蛋白与蓝桉亲缘关系较近,Eu F5H在不同组织中表达水平差异显著,其中半木质化茎中表达水平相对最高。[结论]成功获得了尾叶桉GLU4木质素合成酶基因F5H的全长序列。 展开更多
关键词 尾叶桉 F5H 木质素合成 基因克隆 序列分析 表达模式
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血栓弹力图仪评价丹参多酚酸盐治疗稳定型心绞痛患者的凝血功能和血小板抑制率 被引量:2
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作者 高云龙 吕玉华 +3 位作者 周袁申 晁艳 周厚全 吴新忠 《华南国防医学杂志》 CAS 2020年第12期857-860,共4页
目的应用血栓弹力图仪(thrombelastography,TEG)分析丹参多酚酸盐治疗稳定性心绞痛患者的凝血和血小板功能,评估药物治疗效果。方法选择稳定性心绞痛患者82例,按治疗分为丹参多酚酸盐组(n=26)、氯吡格雷组(n=28)和替格瑞洛组(n=28)。应... 目的应用血栓弹力图仪(thrombelastography,TEG)分析丹参多酚酸盐治疗稳定性心绞痛患者的凝血和血小板功能,评估药物治疗效果。方法选择稳定性心绞痛患者82例,按治疗分为丹参多酚酸盐组(n=26)、氯吡格雷组(n=28)和替格瑞洛组(n=28)。应用TEG测定丹参多酚酸盐用药前后凝血指标及二磷酸腺苷(adenonisine disphosphate,ADP)诱导的血小板聚集功能,应用Sysmex凝血分析仪分析凝血功能,应用Sysmex全血分析仪测定血小板计数。应用TEG测定氯吡格雷及替格瑞洛用药后ADP诱导的血小板聚集功能。结果丹参多酚酸盐组用药前后TEG的凝血指标、凝血功能和血小板计数无差异(P>0.05);其抗血小板有效率为80.77%,ADP诱导的血小板聚集抑制率(48.50%±21.60%)明显低于氯吡格雷组(60.24%±15.62%)和替格瑞洛组(80.90%±18.77%);其药物使用后残余血块强度(35.67 mm±12.45 mm)明显高于氯吡格雷组(32.60 mm±8.34 mm)和替格瑞洛组(22.09 mm±13.06 mm)(P<0.05)。结论丹参多酚酸盐可抑制ADP诱导的血小板聚集,且不影响凝血功能,药效较氯吡格雷和替格瑞洛温和。 展开更多
关键词 血栓弹力图仪 丹参多酚酸盐 稳定性心绞痛
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基于微信企业号的机房报警信息推送平台研究 被引量:5
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作者 刘淑影 晁妍 +1 位作者 王静 曾涛 《重庆科技学院学报(自然科学版)》 CAS 2019年第3期94-96,103,共4页
保证学校中心机房的安全运行是智慧校园建设的重要环节,中心机房一旦出现异常情况,必须及时发出报警信息。鉴于常用的报警信息短信发送方式存在的不足,研究开发了基于微信企业号的机房智能报警信息推送平台。介绍了此平台的基本框架及... 保证学校中心机房的安全运行是智慧校园建设的重要环节,中心机房一旦出现异常情况,必须及时发出报警信息。鉴于常用的报警信息短信发送方式存在的不足,研究开发了基于微信企业号的机房智能报警信息推送平台。介绍了此平台的基本框架及各项功能的实现机制。 展开更多
关键词 智慧校园 机房监控 报警信息 信息推送平台 微信企业号
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