OBJECTIVE： To assess the efficacy and safety of Yunxiangjing （YXJ）, derived from Chinese herbal medicine, in the management of acute radiation-induced proctitis （ARIP） in patients with pelvic malignancy. METHODS...OBJECTIVE： To assess the efficacy and safety of Yunxiangjing （YXJ）, derived from Chinese herbal medicine, in the management of acute radiation-induced proctitis （ARIP） in patients with pelvic malignancy. METHODS： Forty-eight patients with grade 2 ARIP were administered YXJ as an enema （I ： 30 dilution） for 2 weeks and followed up for 2 years. All were a sessed for response and ARIP grade. Quality of life （QOL） was assessed with the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30. RESULTS： Of the 48 patients, six （12.5%） achieved complete remission of ARIP and 28 （58.3%） showed a decrease from grade 2 to grade 1 ARIR No patient experienced a grade 〉3 toxicity. At the end of radio- therapy, patients showed significant improvements in QOL （P 〈 0.05）. Two years after treatment, 46 patients showed no late toxicity, with only two experiencing grade 1 late toxicity. CONCLUSION; YXJ can be used as an enema to manage acute radiation-induced proctitis in cancer patients undergoing radiotherapy. These findings suggest that YXJ enema may be an alternative treatment of ARIP.展开更多
随着城市机动车保有量的急剧增加,城市停车供需矛盾日益显著,路侧违章停车现象也更加突显。为探究路侧违章停车的分布规律及形成原因,结合GIS(geographic information system,地理信息系统)空间分析和聚类分析,提出了一种基于网格K-mean...随着城市机动车保有量的急剧增加,城市停车供需矛盾日益显著,路侧违章停车现象也更加突显。为探究路侧违章停车的分布规律及形成原因,结合GIS(geographic information system,地理信息系统)空间分析和聚类分析,提出了一种基于网格K-means(K均值)聚类分析的违停黑点识别方法。利用南京市秦淮区2021年的路侧违停数据识别出该区域的路侧违停黑点,据此分析违停黑点的道路环境特征,提取出老旧小区、购物广场、旅游景点三大典型违停场景,采用问卷调查的方法,总结出从众心理、路侧停车泊位供应不足、公共停车场距离较远、公共停车场收费标准较高、停车意识和法制观念淡薄、管理部门监督执法不严格等六大路侧违章停车的主要成因,为相关部门制定政策措施提供理论依据。展开更多
基金Supported by the Scientific Research Fund of the Administration of Traditional Chinese Medicine of Guangxi Province of China:The clinical trial of Chinese Herbal Formula Yunxiangjing Enemas on the treatment of Acute Radiation-Induced Proctitis(No.gzzc 1165)
文摘OBJECTIVE： To assess the efficacy and safety of Yunxiangjing （YXJ）, derived from Chinese herbal medicine, in the management of acute radiation-induced proctitis （ARIP） in patients with pelvic malignancy. METHODS： Forty-eight patients with grade 2 ARIP were administered YXJ as an enema （I ： 30 dilution） for 2 weeks and followed up for 2 years. All were a sessed for response and ARIP grade. Quality of life （QOL） was assessed with the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30. RESULTS： Of the 48 patients, six （12.5%） achieved complete remission of ARIP and 28 （58.3%） showed a decrease from grade 2 to grade 1 ARIR No patient experienced a grade 〉3 toxicity. At the end of radio- therapy, patients showed significant improvements in QOL （P 〈 0.05）. Two years after treatment, 46 patients showed no late toxicity, with only two experiencing grade 1 late toxicity. CONCLUSION; YXJ can be used as an enema to manage acute radiation-induced proctitis in cancer patients undergoing radiotherapy. These findings suggest that YXJ enema may be an alternative treatment of ARIP.
文摘随着城市机动车保有量的急剧增加,城市停车供需矛盾日益显著,路侧违章停车现象也更加突显。为探究路侧违章停车的分布规律及形成原因,结合GIS(geographic information system,地理信息系统)空间分析和聚类分析,提出了一种基于网格K-means(K均值)聚类分析的违停黑点识别方法。利用南京市秦淮区2021年的路侧违停数据识别出该区域的路侧违停黑点,据此分析违停黑点的道路环境特征,提取出老旧小区、购物广场、旅游景点三大典型违停场景,采用问卷调查的方法,总结出从众心理、路侧停车泊位供应不足、公共停车场距离较远、公共停车场收费标准较高、停车意识和法制观念淡薄、管理部门监督执法不严格等六大路侧违章停车的主要成因,为相关部门制定政策措施提供理论依据。
