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Hydrodynamic performance of KCS ship in steady turning:experimental and numerical studies
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作者 bowen zhao Hao Gu +3 位作者 Xinyan Yu Hongyang zhao Zhiguo Yang Bin Huang 《Acta Mechanica Sinica》 2025年第8期65-88,共24页
The turning performance of a ship is an important aspect of its maneuverability,and accurately predicting the hydrodynamic forces during ship turning motion is of great significance for the safe maneuvering design of ... The turning performance of a ship is an important aspect of its maneuverability,and accurately predicting the hydrodynamic forces during ship turning motion is of great significance for the safe maneuvering design of ships.This paper investigated the hydrodynamic performance of a KRISO container ship in steady turning using experimental and numerical approaches.The rotating arm tests were carried out in rotating arm basin of Zhejiang University,while the numerical simulations were conducted in commercial computational fluid dynamics software.Hydrodynamic forces and moments,hull surface wave height,wave patterns,and vorticity are studied under different velocities,radii,and drift angles.The results show that the increase in velocity has a significant impact on the forces and moments of the hull.The changes in longitudinal and transverse forces reflect the complex fluid dynamic interactions between the hull and water.Under conditions of small radius and large drift angle,the hull experiences greater forces and moments,indicating that stability and maneuverability will be more challenged during sudden turns.This study can provide experimental data and numerical simulation references for the research of ship turning maneuvers. 展开更多
关键词 Hydrodynamic performance KRISO container ship Steady turning Rotating arm test Numerical simulation Computational fluid dynamics
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Large Ensemble Simulations of Climate Models for Climate Change Research:A Review
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作者 Pengfei LIN Lu YANG +7 位作者 bowen zhao Hailong LIU Pengfei WANG Wenrong BAI Jing MA Jilin WEI Chenyang JIN Yuewen DING 《Advances in Atmospheric Sciences》 2025年第5期825-841,共17页
In recent decades,large ensemble simulation(LENS)or super-large ensemble simulation(SLENS)experiments with climate models,including the simulation of both the historical and future climate,have been increasingly explo... In recent decades,large ensemble simulation(LENS)or super-large ensemble simulation(SLENS)experiments with climate models,including the simulation of both the historical and future climate,have been increasingly exploited in the fields of climate change,climate variability,climate projection,and beyond.This paper provides an overview of LENS in climate systems.It delves into its definition,initialization,significance,and scientific concerns.Additionally,its development history and relevant theories,methods,and primary fields of application are also reviewed.Conclusions obtained from single-model LENS can be more robust compared with those from ensemble simulations with smaller numbers of members.The interactions among model biases,forced responses,and internal variabilities,which serve as the added value in LENS,are highlighted.Finally,we put forward the future trajectory of LENS with climate or Earth system models(ESMs).Super-large ensemble simulation,high-resolution LENS,LENS employing ESMs,and combining LENS with artificial intelligence,will greatly promote the study of climate and related applications. 展开更多
关键词 large ensemble internal variability climate system model climate change external forcing
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Genetic basis of the mucilage secretion ability associated with nitrogen fixation from aerial roots of maize inbred lines under low nitrogen conditions
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作者 bowen zhao Xin Hou +16 位作者 Zhongliang Yu Ronghui Zhang Huixin Teng Ziqiong Yang Jianju He Huijuan Wang Zhihao Song Jiankang Zheng Bolin Song Shiwei Ma Doudou Sun Xiaowei Fan Jingyang Gao Zijian Zhou Jiafa Chen Pei Jing Jianyu Wu 《The Crop Journal》 2025年第2期432-443,共12页
Recent studies have shown that mucilage secretion from aerial roots is an essential feature of modern maize inbred lines,with some retaining the nitrogen-fixing capabilities of ancient landraces.To explore the genetic... Recent studies have shown that mucilage secretion from aerial roots is an essential feature of modern maize inbred lines,with some retaining the nitrogen-fixing capabilities of ancient landraces.To explore the genetic basis of nitrogen fixation in mucilage and its evolution from teosinte(Zea mays ssp.mexicana)to modern maize,we developed a recombinant inbred line(RIL)population from teosinte and cultivated it under low-nitrogen conditions.Large-scale,multi-year,and multi-environment analyses of RIL-Teo,Doubled Haploid-A(DH-A),Doubled Haploid-B(DH-B),and association populations led to the identification of 15 quantitative trait loci(QTL),68 quantitative trait nucleotides(QTN),and 59 candidate genes linked to mucilage secretion from aerial roots.Functional verification of the candidate gene ZmAco3,which is associated with mucilage secretion in aerial roots,demonstrated that deletion of this gene resulted in a reduction in mucilage secretion in aerial roots.In addition,most maize inbred lines exhibited stronger mucilage secretion from aerial roots under low-nitrogen conditions than under normal-nitrogen conditions.We categorized mucilage secretion into constitutive and low-nitrogen-inducible types.Through genotype-by-environment interaction studies,8 QTL,16 QTN,and 19 candidate genes were identified,revealing the genetic mechanisms underlying mucilage secretion under low-nitrogen conditions.These findings provide a comprehensive genetic analysis of the mucilage-secreting ability of maize aerial roots,contributing to our understanding of nitrogen fixation and offering potential avenues for enhancing nitrogen fixation in modern maize lines.This research advances knowledge of plant nutrient acquisition strategies and has implications for sustainable agricultural practices. 展开更多
关键词 Biological nitrogen fixation Maize aerial root Mucilage secretion ability Low nitrogen Candidate genes
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科学可视化应用于药物分析实验教学——以葡萄糖的鉴别为例 被引量:1
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作者 陈睿婷 郑艳洁 +4 位作者 林小燕 王彦霖 许玉娜 赵博文 陈伟 《大学化学》 CAS 2023年第12期75-85,共11页
以葡萄糖鉴别为例,讲述了将科学可视化引入药物分析实验的教学设计和视频制作流程。以图片和视频的方式,形象生动地展示了实验原理、操作过程和实验现象,增加了课程的趣味性和吸引力。拍摄制作的一系列相关视频已应用于课堂教学并发布... 以葡萄糖鉴别为例,讲述了将科学可视化引入药物分析实验的教学设计和视频制作流程。以图片和视频的方式,形象生动地展示了实验原理、操作过程和实验现象,增加了课程的趣味性和吸引力。拍摄制作的一系列相关视频已应用于课堂教学并发布于视频网站,取得了较好的教学效果,并实现了更大范围的共享和交流。 展开更多
关键词 可视化教学 教学改革 药物鉴别 科学摄影 教学视频
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LICOM Model Datasets for the CMIP6 Ocean Model Intercomparison Project 被引量:16
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作者 Pengfei LIN Zhipeng YU +14 位作者 Hailong LIU Yongqiang YU Yiwen LI Jirong JIANG Wei XUE Kangjun CHEN Qian YANG bowen zhao Jilin WEI Mengrong DING Zhikuo SUN Yaqi WANG Yao MENG Weipeng ZHENG Jinfeng MA 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2020年第3期239-249,共11页
The datasets of two Ocean Model Intercomparison Project(OMIP)simulation experiments from the LASG/IAP Climate Ocean Model,version 3(LICOM3),forced by two different sets of atmospheric surface data,are described in thi... The datasets of two Ocean Model Intercomparison Project(OMIP)simulation experiments from the LASG/IAP Climate Ocean Model,version 3(LICOM3),forced by two different sets of atmospheric surface data,are described in this paper.The experiment forced by CORE-II(Co-ordinated Ocean–Ice Reference Experiments,Phase II)data(1948–2009)is called OMIP1,and that forced by JRA55-do(surface dataset for driving ocean–sea-ice models based on Japanese 55-year atmospheric reanalysis)data(1958–2018)is called OMIP2.First,the improvement of LICOM from CMIP5 to CMIP6 and the configurations of the two experiments are described.Second,the basic performances of the two experiments are validated using the climatological-mean and interannual time scales from observation.We find that the mean states,interannual variabilities,and long-term linear trends can be reproduced well by the two experiments.The differences between the two datasets are also discussed.Finally,the usage of these data is described.These datasets are helpful toward understanding the origin system bias of the fully coupled model. 展开更多
关键词 OMIP CMIP6 ocean sea-ice model model bias
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Eddy-resolving Simulation of CAS-LICOM3 for Phase 2 of the Ocean Model Intercomparison Project 被引量:8
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作者 Yiwen LI Hailong LIU +15 位作者 Mengrong DING Pengfei LIN Zipeng YU Yongqiang YU Yao MENG Yunlong LI Xiaodong JIAN Jinrong JIANG Kangjun CHEN Qian YANG Yaqi WANG bowen zhao Jilin WEI Jinfeng MA Weipeng ZHENG and Pengfei WANG 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2020年第10期1067-1080,共14页
A 61-year(1958–2018)global eddy-resolving dataset for phase 2 of the Ocean Model Intercomparison Project has been produced by the version 3 of Chinese Academy of Science,the State Key Laboratory of Numerical Modeling... A 61-year(1958–2018)global eddy-resolving dataset for phase 2 of the Ocean Model Intercomparison Project has been produced by the version 3 of Chinese Academy of Science,the State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics/Institute of Atmospheric Physics(LASG/IAP)Climate system Ocean Model(CAS-LICOM3).The monthly and a part of the surface daily data in this study can be accessed on the Earth System Grid Federation(ESGF)node.Besides the details of the model and experiments,the evolutions and spatial patterns of large-scale and mesoscale features are also presented.The mesoscale features are reproduced well in the high-resolution simulation,as the mesoscale activities can contribute up to 50%of the total SST variability in eddy-rich regions.Also,the large-scale circulations are remarkably improved compared with the low-resolution simulation,such as the climatological annual mean SST(the RMSE is reduced from 0.59°C to 0.47°C,globally)and the evolution of Atlantic Meridional Overturning Circulation.The preliminary evaluation also indicates that there are systematic biases in the salinity,the separation location of the western boundary currents,and the magnitude of eddy kinetic energy.All these biases are worthy of further investigation. 展开更多
关键词 eddy-resolving dataset mesoscale eddies CAS-LICOM3 OMIP
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Highly efficient and stable CuZr-based metallic glassy catalysts for azo dye degradation 被引量:6
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作者 bowen zhao Zhengwang Zhu +2 位作者 Xin Dong Qin Zhengkun Li Haifeng Zhang 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2020年第11期88-97,共10页
Metallic glasses with the unique disordered atomic structure and metastable nature have been recently applied to degrade the azo dyes and other organic pollutants based on their superior catalytic performance.In this ... Metallic glasses with the unique disordered atomic structure and metastable nature have been recently applied to degrade the azo dyes and other organic pollutants based on their superior catalytic performance.In this work,the functional properties of six Cu Zr-based metallic glassy ribbons with the different nominal components in degrading Acid OrangeⅡ(AOⅡ)azo dyes were investigated.The Cu47.5Zr46Al6.5 metallic glassy ribbons could exhibit the more advanced catalytic performance for degradation process,which could completely degrade azo dye aqueous solution within 30 min.Additionally,the Cu47.5Zr46Al6.5 metallic glassy ribbons also showed the excellent cyclic stability along with approximately 97.68%degradation efficiency after 10 cycles.These excellent catalytic performance and stability are closely related to the synergistic effect of exposed copper nanoparticles and produced copper oxides in the reaction,which contributes to accelerate the generation of more hydroxyl radicals(·OH)to react with dye molecules.Our findings can be able to develop a novel potential metallic glassy material for the functional application of wastewater treatment. 展开更多
关键词 Metallic glasses Catalytic performance DEGRADATION Azo dyes
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The Super-large Ensemble Experiments of CAS FGOALS-g3 被引量:3
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作者 Pengfei LIN bowen zhao +15 位作者 Jilin WEI Hailong LIU Wenxia ZHANG Xiaolong CHEN Jie JIANG Mengrong DING Wenmin MAN Jinrong JIANG Xu ZHANG Yuewen DING Wenrong BAI Chenyang JIN Zipeng YU Yiwen LI Weipeng ZHENG Tianjun ZHOU 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2022年第10期1746-1765,I0021-I0025,共25页
A super-large ensemble simulation dataset with 110 members has been produced by the fully coupled model FGOALS-g3 developed by researchers at the Institute of Atmospheric Physics,Chinese Academy of Sciences.This is th... A super-large ensemble simulation dataset with 110 members has been produced by the fully coupled model FGOALS-g3 developed by researchers at the Institute of Atmospheric Physics,Chinese Academy of Sciences.This is the first dataset of large ensemble simulations with a climate system model developed by a Chinese modeling center.The simulation has the largest realizations up to now worldwide in terms of single-model initial-condition large ensembles.Each member includes a historical experiment(1850-2014)and an experiment(2015-99)under the very high greenhouse gas emissions Shared Socioeconomic Pathway scenario(SSP5-8.5).The dataset includes monthly and daily temperature,precipitation,and other variables,requiring storage of 275 TB.Additionally,the surface air temperature(SAT)and land precipitation simulated by the FGOALS-g3 super-large ensemble have been validated and projected.The ensemble can capture the response of SAT and land precipitation to external forcings well,and the internal variabilities can be quantified.The availability of more than 100 realizations will help researchers to study rare events and improve the understanding of the impact of internal variability on forced climate changes. 展开更多
关键词 large ensemble forced response internal variability climate change
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Consistent Scaling Exponents at the Deconfined Quantum-Critical Point 被引量:3
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作者 Anders W.Sandvik bowen zhao 《Chinese Physics Letters》 SCIE CAS CSCD 2020年第5期93-97,共5页
We report a quantum Monte Carlo study of the phase transition between antiferromagnetic and valence-bond solid ground states in the square-lattice S=1/2 J-Q model.The critical correlation function of the Q terms gives... We report a quantum Monte Carlo study of the phase transition between antiferromagnetic and valence-bond solid ground states in the square-lattice S=1/2 J-Q model.The critical correlation function of the Q terms gives a scaling dimension corresponding to the value v=0.455±0.002 of the correlation-length exponent.This value agrees with previous(less precise)results from conventional methods,e.g.,finite-size scaling of the nearcritical order parameters.We also study the Q-derivatives of the Binder cumulants of the order parameters for L2 lattices with L up to 448.The slope grows as L1/v with a value of v consistent with the scaling dimension of the Q term.There are no indications of runaway flow to a first-order phase transition.The mutually consistent estimates of v provide compelling support for a continuous deconfined quantum-critical point. 展开更多
关键词 transition. CONFINED SCALING
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FGOALS-g3 Model Datasets for CMIP6 Flux-Anomaly-Forced Model Intercomparison Project 被引量:2
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作者 Yaqi WANG Zipeng YU +14 位作者 Pengfei LIN Hailong LIU Jiangbo JIN Lijuan LI Yanli TANG Li DONG Kangjun CHEN Yiwen LI Qian YANG Mengrong DING Yao MENG bowen zhao Jilin WEI Jinfeng MA and Zhikuo SUN 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2020年第10期1093-1101,共9页
The Flux-Anomaly-Forced Model Intercomparison Project(FAFMIP)is an endorsed Model Intercomparison Project in phase 6 of the Coupled Model Intercomparison Project(CMIP6).The goal of FAFMIP is to investigate the spread ... The Flux-Anomaly-Forced Model Intercomparison Project(FAFMIP)is an endorsed Model Intercomparison Project in phase 6 of the Coupled Model Intercomparison Project(CMIP6).The goal of FAFMIP is to investigate the spread in the atmosphere–ocean general circulation model projections of ocean climate change forced by increased CO2,including the uncertainties in the simulations of ocean heat uptake,global mean sea level rise due to ocean thermal expansion and dynamic sea level change due to ocean circulation and density changes.The FAFMIP experiments have already been conducted with the Flexible Global Ocean–Atmosphere–Land System Model,gridpoint version 3.0(FGOALS-g3).The model datasets have been submitted to the Earth System Grid Federation(ESGF)node.Here,the details of the experiments,the output variables and some baseline results are presented.Compared with the preliminary results of other models,the evolutions of global mean variables can be reproduced well by FGOALS-g3.The simulations of spatial patterns are also consistent with those of other models in most regions except the North Atlantic and the Southern Ocean,indicating large uncertainties in the regional sea level projections of these two regions. 展开更多
关键词 FAFMIP CMIP6 global mean sea level rise dynamic sea level change
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DNA提取过程中混入的实验室空气微生物DNA定量
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作者 陈天达 张婷婷 +2 位作者 杨娅楠 赵柏闻 吴崇明 《生物工程学报》 CAS CSCD 北大核心 2020年第12期2541-2547,共7页
元基因组测序方法为微生物研究提供了有力的工具。但其中的DNA提取过程,会不可避免地混入实验室中的空气微生物。这些微生物DNA,是否会对一些极微量的元基因组检测(如皮肤样本等)结果造成影响,有多大影响,仍没有明确结论。本研究首先收... 元基因组测序方法为微生物研究提供了有力的工具。但其中的DNA提取过程,会不可避免地混入实验室中的空气微生物。这些微生物DNA,是否会对一些极微量的元基因组检测(如皮肤样本等)结果造成影响,有多大影响,仍没有明确结论。本研究首先收集了实验室空气样品,用16S rRNA引物建立了基于qPCR的标准曲线,并检测了在开放环境下提取DNA过程中可掺杂的环境微生物DNA量。然后在开放环境下提取纯水DNA样品并进行元基因组分析,以确定掺杂环境微生物的种类。最后分别在生物安全柜和实验室开放环境下提取皮肤样本,并用鸟枪测序方法对样本的微生物组成进行分析,以评估掺杂环境微生物对元基因组检测结果的影响。结果显示,在实验室开放环境的DNA提取过程中,环境微生物的DNA残留可达28.9 pg,可达某些极微量样本DNA总量的30%。元基因组分析显示,样品中掺杂的环境微生物主要是痤疮杆菌Cutibacterium acnes、大肠杆菌Escherichia coli等皮肤常见细菌。与洁净皮肤样本的信息相比,开放环境下提取掺杂了数十种环境微生物,并导致主要菌种的丰度大幅降低,从而影响结果的真实性。因此,微量样品的DNA提取应在洁净环境下执行。 展开更多
关键词 痕量DNA 定量 实验室环境 qPCR 微生物组 皮肤样本
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Dynamic Analysis of Pipeline Lifting Operations for Different Current Velocities and Wave Heights 被引量:1
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作者 Dapeng Zhang bowen zhao Keqiang Zhu 《Fluid Dynamics & Materials Processing》 EI 2023年第3期603-617,共15页
Pipelines are widely used for transporting oil resources in the context of offshore oil exploitation.The pipeline stress-strength analysis is an important stage in related design and ensuing construction techniques.In... Pipelines are widely used for transporting oil resources in the context of offshore oil exploitation.The pipeline stress-strength analysis is an important stage in related design and ensuing construction techniques.In this study,assuming representative work environment parameters,pipeline lifting operations are investigated numerically.More specifically,a time-domain coupled dynamic analysis method is used to conduct a hydrodynamic analysis under different current velocities and wave heights.The results show that proper operation requires the lifting points are reasonably set in combination with the length of the pipeline and the position of the lifting device on the construction ship.The impact of waves on the pipeline is limited,however lifting operations under strong wind and waves should be avoided as far as possible. 展开更多
关键词 PIPELINE OrcaFlex hydrodynamic analysis lifting operation
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Green strategy of scaleably synthesizing copper nanocomposites with remarkable catalytic activity for wastewater treatment
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作者 bowen zhao Hailong Li +6 位作者 Zhengkun Li Shaofan Ge Xindong Qin Shiming Zhang Aimin Wang Haifeng Zhang Zhengwang Zhu 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2021年第36期158-166,共9页
The functional copper nanocomposites(Cu NCs)have received increasing attention in the environmental catalysis application for wastewater treatment due to their superior catalytic activity and reactivity.However,overco... The functional copper nanocomposites(Cu NCs)have received increasing attention in the environmental catalysis application for wastewater treatment due to their superior catalytic activity and reactivity.However,overcoming the pH limitations towards the neutral and alkaline wastewater remains a tricky challenge.In this work,we demonstrate a green strategy to synthesize Cu NCs with coexistence of active Cu,Cu_(2)O and ZrO_(2)by self-propagating combustion of metallic glassy ribbons,which exhibit the extremely superior catalytic performance for degradation reaction,providing full conversion of organic dyes completely to the environmental friendly small species(efficiency>99%)under acidic,neutral and alkaline conditions.Compared with all other catalysts developed thus far,the novel Cu NCs catalysts with more active sites present much enhanced catalytic capability of degradation efficiency without the use of any chemical reagents for neutral and alkaline organic dye solutions.The possible decomposition pathways of organic dyes for different p H systems were systematically investigated.More importantly,the two kinds of catalytic mechanism related to high reactivity of nanoscale Cu/Cu_(2)O and strong oxidizing capability of activated·OH/·O_(2)^(-)radicals can also be successfully confirmed under different pH conditions.The green synthetic approach can be extended to design the various M-based nanocomposites(M=Fe,Co,Ni,Ag,Pd)as efficient catalysts for the functional applications of many chemical reactions. 展开更多
关键词 Copper nanocomposites Metallic glasses Self-propagating combustion Catalytic degradation Electron transfer Organic dyes
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An efficient CuZr-based metallic glasses electrode material for electrocatalytic degradation of azo dyes
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作者 Zhiwang Deng bowen zhao +4 位作者 Songtao Li Zhengkun Li Shiming Zhang Kewei Zhang Zhengwang Zhu 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2024年第2期537-546,共10页
Metallic glasses have received a lot of attention on wastewater treatment due to their unique atomic structure,and the use of metallic glasses as electrodes has produced unexpected electrocatalytic degradation effects... Metallic glasses have received a lot of attention on wastewater treatment due to their unique atomic structure,and the use of metallic glasses as electrodes has produced unexpected electrocatalytic degradation effects for many pollutants through combining with electrochemical technology.However,it still is a formidable challenge to find a metallic glass electrode material with both efficient and clean for the catalytic degradation of pollutants.In this work,the Cu_(55)Zr_(45)metallic glassy ribbons are used as an electrode to degrade azo dyes and show the excellent degradation effect,which can reach 95.6%within 40 min.In the degradation process,almost no additives are produced and Cu_(55)Zr_(45)metallic glassy ribbons have excellent effects under different pH conditions.Meanwhile,it exhibits good stability for degradation efficiency during the 8 cycle degradation tests of the amorphous alloy electrode.When the copper nanoparticles are exposed on the surface of the ribbons,the oxidized copper obtained synergistically produce activated radicals is the primary degradation mechanism,where the auxiliary degradation mechanisms include electron transfer and the promotion of active chlorine.This research develops a new type of electrode material for wastewater treatment,and the economy and high efficiency of Cu55Zr45metallic glass endow it the expandable functional applications. 展开更多
关键词 Metallic glasses Azo dyes ELECTROCATALYTIC DEGRADATION Oxidized copper
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Provably Secure APK Redevelopment Authorization Scheme in the Standard Model
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作者 Daofeng Li Mingxing Luo +1 位作者 bowen zhao Xiangdong Che 《Computers, Materials & Continua》 SCIE EI 2018年第9期447-465,共19页
The secure issues of APK are very important in Android applications.In order to solve potential secure problems and copyrights issues in redevelopment of APK files,in this paper we propose a new APK redevelopment mech... The secure issues of APK are very important in Android applications.In order to solve potential secure problems and copyrights issues in redevelopment of APK files,in this paper we propose a new APK redevelopment mechanism(APK-SAN).By exploring sanitizable signature technology,APK-SAN allows the original developer to authorize specified modifier who can redevelop the designated source code of APK files.Our scheme does not require interactions between the developer and modifiers.It can reduce the communication overhead and computational overhead for developers.Especially,the signature of redeveloped APK files is valid and maintains the copyrights.The proposed APK-SAN signature can effectively protect the security of the redeveloped APK files and copyrights of the developer and modifier. 展开更多
关键词 Sanitizable SIGNATURE APK SIGNATURE mechanism REDEVELOPMENT ID-BASED SIGNATURE SCHEME
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Eugenol targeting CrtM inhibits the biosynthesis of staphyloxanthin in Staphylococcus aureus
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作者 Jiang Chang Bo Chen +7 位作者 Zeqian Du bowen zhao Jiahui Li Ziyi Li Kannappan Arunachalam Ting Shi Dongqing Wei Chunlei Shi 《Food Science and Human Wellness》 SCIE CSCD 2024年第3期1368-1377,共10页
Staphylococcus aureus is a serious foodborne pathogen threatening food safety and public health.Especially the emergence of methicillin-resistant Staphylococcus aureus(MRSA)increased the difficulty of S.aureus treatme... Staphylococcus aureus is a serious foodborne pathogen threatening food safety and public health.Especially the emergence of methicillin-resistant Staphylococcus aureus(MRSA)increased the difficulty of S.aureus treatment.Staphyloxanthin is a crucial virulence factor of S.aureus.Blocking staphyloxanthin production could help the host immune system counteract the invading S.aureus cells.In this study,we first screened for staphyloxanthin inhibitors using a virtual screening method.The outcome of the virtual screening method resulted in the identification of eugenol(300μg/mL),which significantly inhibits the staphyloxanthin production in S.aureus ATCC 29213,S.aureus Newman,MRSA ATCC 43300 and MRSA ATCC BAA1717by 84.2%,63.5%,68.1%,and 79.5%,respectively.The outcome of the growth curve assay,field-emission scanning electron,and confocal laser scanning microscopy analyses confirmed that eugenol at the test concentration did not affect the morphology and growth of S.aureus.Moreover,the survival rate of S.aureus ATCC 29213 and MRSA ATCC 43300 under H_(2)O_(2) pressure decreased to 51.9%and 45.5%in the presence of eugenol,respectively.The quantitative RT-PCR and molecular simulation studies revealed that eugenol targets staphyloxanthin biosynthesis by downregulating the transcription of the crtM gene and inhibiting the activity of the CrtM enzyme.Taken together,we first determined that eugenol was a prominent compound for staphyloxanthin inhibitor to combat S.aureus especially MRSA infections. 展开更多
关键词 Staphylococcus aureus Staphyloxanthin EUGENOL Virtual screening 4 4’-Diapophytoene synthase(CrtM)
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Utilizing auxin dwarf genes to optimize seed yield and lodging resistance in rapeseed
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作者 Hongxiang Lou Yan Peng +10 位作者 Chunyun Wang Zongkai Wang bowen zhao Ali Mahmoud El-Badri Maria Batool Bo Wang Jing Wang Zhenghua Xu Jie zhao Jie Kuai Guangsheng Zhou 《The Crop Journal》 SCIE CSCD 2024年第4期1208-1221,共14页
Direct-seeding rapeseed production at high plant density raises the risk of lodging.We investigated the use of dwarf genes to improve rapeseed plant architecture to balance yield and lodging.Three genotypes with diffe... Direct-seeding rapeseed production at high plant density raises the risk of lodging.We investigated the use of dwarf genes to improve rapeseed plant architecture to balance yield and lodging.Three genotypes with different plant architectures(dwarf sca^(HS5),semi-dwarf+/sca^(HS5),and tall ^(HS5))were evaluated under varying nitrogen rates(N1,N2,and N3:120,240,and 360 kg N ha^(-1))and plant densities(D1,D2,and D3:15,45,and 75 plants m^(-2))from 2019 to 2022.The results showed that increasing N rate positively influenced yield while decreasing lodging resistance in all genotypes.Increasing plant density(D2-D3)enhanced lodging resistance and yield in sca^(HS5) and+/sca^(HS5),but reduced yield in ^(HS5).Compared to the two parents,+/sca^(HS5) exhibited moderate expressions of IAA3,GH3.15,and SAUR30 in stems under N2D3,resulting in reduced plant height and increased compactness.Additionally,+/sca^(HS5) had a thicker silique layer than ^(HS5) by 14.7%,and it had a significant correlation between branch height/angle and yield.Increasing N rate led to increased lignin and pectin contents,while cellulose content decreased.Increasing plant density resulted in greater stem cellulose content and CSLA3/7 expression in sca^(HS5) and+/sca^(HS5),but decreased in ^(HS5).Compared to ^(HS5),+/sca^(HS5) exhibited higher expressions of ARAD1 and GAUT4,along with a 51.1%increase in pectin content,leading to improved lodging resistance under N2D3.Consequently,+/sca^(HS5) showed a 46.4%higher yield and 38.9%lodging resistance than ^(HS5) under N2D3,while sca^(HS5) demonstrated strong lodging resistance but lower yield potential.Overall,this study underscores the potential of utilizing auxin dwarf genes to optimize the trade-off between yield and lodging resistance in rapeseed and the possibility of maximizing yield potential by optimizing the plant architecture of+/sca^(HS5) through nitrogen reduction and dense planting. 展开更多
关键词 RAPESEED Plant density NITROGEN LODGING AUXIN
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Emergent O(4) symmetry at the phase transition from plaquette-singlet to antiferromagnetic order in quasi-two-dimensional quantum magnets
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作者 Guangyu Sun Nvsen Ma +2 位作者 bowen zhao Anders WSandvik Zi Yang Meng 《Chinese Physics B》 SCIE EI CAS CSCD 2021年第6期570-582,共13页
Recent experiments [Guo et al., Phys. Rev. Lett. 124 206602(2020)] on thermodynamic properties of the frustrated layered quantum magnet SrCu_(2)(BO_(3))_(2)-the Shastry–Sutherland material-have provided strong eviden... Recent experiments [Guo et al., Phys. Rev. Lett. 124 206602(2020)] on thermodynamic properties of the frustrated layered quantum magnet SrCu_(2)(BO_(3))_(2)-the Shastry–Sutherland material-have provided strong evidence for a lowtemperature phase transition between plaquette-singlet and antiferromagnetic order as a function of pressure. Further motivated by the recently discovered unusual first-order quantum phase transition with an apparent emergent O(4) symmetry of the antiferromagnetic and plaquette-singlet order parameters in a two-dimensional "checkerboard J-Q" quantum spin model[Zhao et al., Nat. Phys. 15 678(2019)], we here study the same model in the presence of weak inter-layer couplings. Our focus is on the evolution of the emergent symmetry as the system crosses over from two to three dimensions and the phase transition extends from strictly zero temperature in two dimensions up to finite temperature as expected in SrCu_(2)(BO_(3))_(2).Using quantum Monte Carlo simulations, we map out the phase boundaries of the plaquette-singlet and antiferromagnetic phases, with particular focus on the triple point where these two ordered phases meet the paramagnetic phase for given strength of the inter-layer coupling. All transitions are first-order in the neighborhood of the triple point. We show that the emergent O(4) symmetry of the coexistence state breaks down clearly when the interlayer coupling becomes sufficiently large, but for a weak coupling, of the magnitude expected experimentally, the enlarged symmetry can still be observed at the triple point up to significant length scales. Thus, it is likely that the plaquette-singlet to antiferromagnetic transition in SrCu_(2)(BO_(3))_(2) exhibits remnants of emergent O(4) symmetry, which should be observable due to additional weakly gapped Goldstone modes. 展开更多
关键词 quantum phase transitions quantum spin systems emergent symmetry quantum Monte Carlo simulations
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Tunable deconfined quantum criticality and interplay of different valence-bond solid phases
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作者 bowen zhao Jun Takahashi Anders W.Sandvik 《Chinese Physics B》 SCIE EI CAS CSCD 2020年第5期52-65,共14页
We use quantum Monte Carlo simulations to study an S = 1/2 spin model with competing multi-spin interactions. We find a quantum phase transition between a columnar valence-bond solid(cVBS) and a Néel antiferromag... We use quantum Monte Carlo simulations to study an S = 1/2 spin model with competing multi-spin interactions. We find a quantum phase transition between a columnar valence-bond solid(cVBS) and a Néel antiferromagnet(AFM), as in the scenario of deconfined quantum-critical points, as well as a transition between the AFM and a staggered valence-bond solid(sVBS). By continuously varying a parameter, the sVBS–AFM and AFM–cVBS boundaries merge into a direct sVBS–cVBS transition. Unlike previous models with putative deconfined AFM–cVBS transitions, e.g., the standard J–Q model,in our extended J–Q model with competing cVBS and sVBS inducing terms the transition can be tuned from continuous to first-order. We find the expected emergent U(1) symmetry of the microscopically Z4 symmetric cVBS order parameter when the transition is continuous. In contrast, when the transition changes to first-order, the clock-like Z4 fluctuations are absent and there is no emergent higher symmetry. We argue that the confined spinons in the sVBS phase are fracton-like.We also present results for an SU(3) symmetric model with a similar phase diagram. The new family of models can serve as a useful tool for further investigating open questions related to deconfined quantum criticality and its associated emergent symmetries. 展开更多
关键词 quantum phase transitions deconfined quantum criticality quantum spin systems quantum Monte Carlo simulations
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Erratum to:LICOM Model Datasets for the CMIP6 OceanModel Intercomparison ProjectLICOM Model Datasets for the CMIP6 OceanModel Intercomparison Project
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作者 Pengfei LIN Zipeng YU +14 位作者 Hailong LIU Yongqiang YU Yiwen LI Jinrong JIANG Wei XUE Kangjun CHEN Qian YANG bowen zhao Jilin WEI Mengrong DING Zhikuo SUN Yaqi WANG Yao MENG Weipeng ZHENG Jinfeng MA 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2020年第6期662-662,共1页
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