In the RSSI-based positioning algorithm,regarding the problem of a great conflict between precision and cost,a low-power and low-cost synergic localization algorithm is proposed,where effective methods are adopted in ...In the RSSI-based positioning algorithm,regarding the problem of a great conflict between precision and cost,a low-power and low-cost synergic localization algorithm is proposed,where effective methods are adopted in each phase of the localization process and fully use the detective information in the network to improve the positioning precision and robustness.In the ranging period,the power attenuation factor is obtained through the wireless channel modeling,and the RSSI value is transformed into distance.In the positioning period,the preferred reference nodes are used to calculate coordinates.In the position optimization period,Taylor expansion and least-squared iterative update algorithms are used to further improve the location precision.In the positioning,the notion of cooperative localization is introduced,in which the located node satisfying certain demands will be upgraded to a reference node so that it can participate in the positioning of other nodes,and improve the coverage and positioning precision.The results show that on the same network conditions,the proposed algorithm in this paper is similar to the Taylor series expansion algorithm based on the actual coordinates,but much higher than the basic least square algorithm,and the positioning precision is improved rapidly with the reduce of the range error.展开更多
The application of a controllable neutron source for measuring formation porosity in the advancement of nuclear logging has garnered increased attention.The existing porosity algorithm,which is based on the thermal ne...The application of a controllable neutron source for measuring formation porosity in the advancement of nuclear logging has garnered increased attention.The existing porosity algorithm,which is based on the thermal neutron counting ratio,exhibits lower sensitivity in high-porosity regions.To enhance the sensitivity,the effects of elastic and inelastic scattering,which influence the slowing-down of fast neutrons,were theoretically analyzed,and a slowing-down model of fast neutrons was created.Based on this model,a density correction porosity algorithm was proposed based on the relationship between density,thermal neutron counting ratio,and porosity.Finally,the super multifunctional calculation program for nuclear design and safety evaluation(TopMC/SuperMC)was used to create a simulation model for porosity logging,and its applicability was examined.The results demonstrated that the relative error between the calculated and actual porosities was less than 1%,and the influence of deviation in the density measurement was less than 2%.Therefore,the proposed density correction algorithm based on the slowing-down model of fast neutrons can effectively improve the sensitivity in the high-porosity region.This study is expected to serve as a reference for the application of neutron porosity measurements with D–T neutron sources.展开更多
Recently, canopy transpiration （Ec） has been often estimated by xylem sap-flow measurements. However, there is a significant time lag between sap flow measured at the base of the stem and canopy transpiration due to...Recently, canopy transpiration （Ec） has been often estimated by xylem sap-flow measurements. However, there is a significant time lag between sap flow measured at the base of the stem and canopy transpiration due to the capacitive exchange between the transpiration stream and stem water storage. Significant errors will be introduced in canopy conductance （gc） and canopy transpiration estimation if the time lag is neglected. In this study, a cross-correlation analysis was used to quantify the time lag, and the sap flowbased transpiration was measured to pararneterize Jarvistype models of gc and thus to simulate Ec of Populus cathayana using the Penman-Monteith equation. The results indicate that solar radiation （Rs） and vapor pressure deficit （VPD） are not fully coincident with sap flow and have an obvious lag effect; the sap flow lags behind Rs and precedes VPD, and there is a 1-h time shift between Eo and sap flow in the 30-min interval data set. A parameterized Jarvis-type gc model is suitable to predict P. cathayana transpiration and explains more than 80% of the variation observed in go, and the relative error was less than 25%, which shows a preferable simulation effect. The root mean square error （RMSEs） between the predicted and measured Ec were 1.91×10^-3 （with the time lag） and 3.12×10^-3cm h^-1 （without the time lag）. More importantly, Ec simulation precision that incorporates time lag is improved by 6% compared to the results without the time lag, with the mean relative error （MRE） of only 8.32% and the mean absolute error （MAE） of 1.48 × 10^-3 cm h^-1.展开更多
Excessive fat ectopically deposited in the non-adipose tissues is considered as one of the leading causes of myopathy.The aim of this study was to investigate the role of Dihydroartemisinin(DHA)in palmitate(PAL)-incub...Excessive fat ectopically deposited in the non-adipose tissues is considered as one of the leading causes of myopathy.The aim of this study was to investigate the role of Dihydroartemisinin(DHA)in palmitate(PAL)-incubated H9c2 cells(lipotoxicity-induced cell injury model).Cell viability of PAL-treated cells was determined by MTT assay,and apoptotic regulators were examined by qRT-PCR and western blot analysis,in the absence or in the presence of DHA,respectively.Expression levels of miR-133b and Sirt1 were also evaluated by qRT-PCR and western blotting examination.PAL decreased the viability of H9c2 cells and enhanced the expression of apoptotic genes.DHA reversed the effect of PAL on cell viability and lowed the level of Caspase3 and Bax.It also lowered the expression of miR-133b,while enhanced the expression of Bcl-2.Sirt1 was revealed as target of miR-133b through transcriptional regulation and the process was affected by DHA.DHA partially protected against the PAL-induced lipotoxicity by influencing the expression of miR-133b that hindered the activity of Sirt1.DHA may be used as a potential treatment in clinical management for lipotoxicity induced heart complications.展开更多
基金National Natural Science Foundation of China,grant number 62205120,funded this research.
文摘In the RSSI-based positioning algorithm,regarding the problem of a great conflict between precision and cost,a low-power and low-cost synergic localization algorithm is proposed,where effective methods are adopted in each phase of the localization process and fully use the detective information in the network to improve the positioning precision and robustness.In the ranging period,the power attenuation factor is obtained through the wireless channel modeling,and the RSSI value is transformed into distance.In the positioning period,the preferred reference nodes are used to calculate coordinates.In the position optimization period,Taylor expansion and least-squared iterative update algorithms are used to further improve the location precision.In the positioning,the notion of cooperative localization is introduced,in which the located node satisfying certain demands will be upgraded to a reference node so that it can participate in the positioning of other nodes,and improve the coverage and positioning precision.The results show that on the same network conditions,the proposed algorithm in this paper is similar to the Taylor series expansion algorithm based on the actual coordinates,but much higher than the basic least square algorithm,and the positioning precision is improved rapidly with the reduce of the range error.
基金supported by the Anhui Provincial Major Science and Technology Project(No.201903c08020003)the Taishan industrial Experts Program。
文摘The application of a controllable neutron source for measuring formation porosity in the advancement of nuclear logging has garnered increased attention.The existing porosity algorithm,which is based on the thermal neutron counting ratio,exhibits lower sensitivity in high-porosity regions.To enhance the sensitivity,the effects of elastic and inelastic scattering,which influence the slowing-down of fast neutrons,were theoretically analyzed,and a slowing-down model of fast neutrons was created.Based on this model,a density correction porosity algorithm was proposed based on the relationship between density,thermal neutron counting ratio,and porosity.Finally,the super multifunctional calculation program for nuclear design and safety evaluation(TopMC/SuperMC)was used to create a simulation model for porosity logging,and its applicability was examined.The results demonstrated that the relative error between the calculated and actual porosities was less than 1%,and the influence of deviation in the density measurement was less than 2%.Therefore,the proposed density correction algorithm based on the slowing-down model of fast neutrons can effectively improve the sensitivity in the high-porosity region.This study is expected to serve as a reference for the application of neutron porosity measurements with D–T neutron sources.
基金supported by the Qinghai province natural science foundation project(2015-ZJ-902)the Qinghai province science and technology plan program(2014-NK-A4-4)
文摘Recently, canopy transpiration （Ec） has been often estimated by xylem sap-flow measurements. However, there is a significant time lag between sap flow measured at the base of the stem and canopy transpiration due to the capacitive exchange between the transpiration stream and stem water storage. Significant errors will be introduced in canopy conductance （gc） and canopy transpiration estimation if the time lag is neglected. In this study, a cross-correlation analysis was used to quantify the time lag, and the sap flowbased transpiration was measured to pararneterize Jarvistype models of gc and thus to simulate Ec of Populus cathayana using the Penman-Monteith equation. The results indicate that solar radiation （Rs） and vapor pressure deficit （VPD） are not fully coincident with sap flow and have an obvious lag effect; the sap flow lags behind Rs and precedes VPD, and there is a 1-h time shift between Eo and sap flow in the 30-min interval data set. A parameterized Jarvis-type gc model is suitable to predict P. cathayana transpiration and explains more than 80% of the variation observed in go, and the relative error was less than 25%, which shows a preferable simulation effect. The root mean square error （RMSEs） between the predicted and measured Ec were 1.91×10^-3 （with the time lag） and 3.12×10^-3cm h^-1 （without the time lag）. More importantly, Ec simulation precision that incorporates time lag is improved by 6% compared to the results without the time lag, with the mean relative error （MRE） of only 8.32% and the mean absolute error （MAE） of 1.48 × 10^-3 cm h^-1.
基金supported by Nantong Science and Technology Project(MS12018020,MS12018041)Jiangsu Government Scholarship for Overseas Studies(JS-2017-200)+1 种基金the Doctoral Scientific Research Foundation of Nantong University(135420505015)the Natural Science Foundation of the Jiangsu Higher Education Institutions of China(11KJB180010).
文摘Excessive fat ectopically deposited in the non-adipose tissues is considered as one of the leading causes of myopathy.The aim of this study was to investigate the role of Dihydroartemisinin(DHA)in palmitate(PAL)-incubated H9c2 cells(lipotoxicity-induced cell injury model).Cell viability of PAL-treated cells was determined by MTT assay,and apoptotic regulators were examined by qRT-PCR and western blot analysis,in the absence or in the presence of DHA,respectively.Expression levels of miR-133b and Sirt1 were also evaluated by qRT-PCR and western blotting examination.PAL decreased the viability of H9c2 cells and enhanced the expression of apoptotic genes.DHA reversed the effect of PAL on cell viability and lowed the level of Caspase3 and Bax.It also lowered the expression of miR-133b,while enhanced the expression of Bcl-2.Sirt1 was revealed as target of miR-133b through transcriptional regulation and the process was affected by DHA.DHA partially protected against the PAL-induced lipotoxicity by influencing the expression of miR-133b that hindered the activity of Sirt1.DHA may be used as a potential treatment in clinical management for lipotoxicity induced heart complications.
