Ascites formation in solid tumor patients is associatedwith an increased risk of death[1,2].The lack of patho-physiological insight limited the development of targetedtreatment so far.With advances in immune modulatin...Ascites formation in solid tumor patients is associatedwith an increased risk of death[1,2].The lack of patho-physiological insight limited the development of targetedtreatment so far.With advances in immune modulatingtherapies,the inflammatory component of ascites movedinto focus.Experimental approaches targeting immuno-logic dysregulation have shown only limited success[3,4].Therefore,we investigated inflammatory processes ofascites,taking the presence of tumor cells into account,while focusing on gastrointestinal tract malignancies dueto their underrepresentation in literature.展开更多
文摘Ascites formation in solid tumor patients is associatedwith an increased risk of death[1,2].The lack of patho-physiological insight limited the development of targetedtreatment so far.With advances in immune modulatingtherapies,the inflammatory component of ascites movedinto focus.Experimental approaches targeting immuno-logic dysregulation have shown only limited success[3,4].Therefore,we investigated inflammatory processes ofascites,taking the presence of tumor cells into account,while focusing on gastrointestinal tract malignancies dueto their underrepresentation in literature.
