The mining height of a coal seam is a critical factor influencing the detachment,collapse,and formation of the collapse angle of the strata during strata movement.To clarify the mechanism by which mining height affect...The mining height of a coal seam is a critical factor influencing the detachment,collapse,and formation of the collapse angle of the strata during strata movement.To clarify the mechanism by which mining height affects strata movement characteristics,a physical model experiment was conducted based on the geological conditions of the Panel 122104 in Caojiatan Coal Mine in Shaanxi.The experiment examined strata movement at mining heights of 1 m and 10 m,identifying differences in detachment,collapse behavior,and collapse angles under these two conditions.The results indicate the following:Delamination range directly governs collapse patterns,with higher stress concentration accelerating delamination initiation and expanding affected zones.1 m mining height exhibits a“superposed fixed beam”structure with lower strength compared to the“fixed beam+cantilever beam”configuration under 10 m height.A model estimating collapse step shows 9.13%average error.Strata structure dictates collapse angle mechanisms:Pseudo-plastic deformation under 1 m height determines collapse angle through vertical tensile stress boundaries,whereas 10 m height exhibits brittle fracture behavior with collapse angles approximating fracture angles.Periodic collapse volume above working face directly correlates with mine pressure intensity and is positively correlated with the caving step distance,collapse angle,and caving range.These parameters show higher values under 10 m mining height,resulting in more pronounced mine pressure manifestations compared to 1 m conditions.展开更多
Cardiovascular disease is the leading cause of human mortality,and calcified tissue blocking blood vessels is the main cause of major adverse cardiovascular events(MACE).Rotational Atherectomy(RA)is a minimally invasi...Cardiovascular disease is the leading cause of human mortality,and calcified tissue blocking blood vessels is the main cause of major adverse cardiovascular events(MACE).Rotational Atherectomy(RA)is a minimally invasive catheterbased treatment method that involves high-speed cutting of calcified tissue using miniature tools for removal.However,the cutting forces,heat,and debris can induce tissue damage and give rise to serious surgical complications.To enhance the effectiveness and efficiency of RA,a novel eccentric rotational cutting tool,with one side comprising axial and circumferential staggered micro-blades,was designed and fabricated in this study.In addition,a series of experiments were conducted to analyze their performance across five dimensions:tool kinematics,force,temperature,debris,and surface morphology of the specimens.Experimental results show that the force,temperature and debris size of the novel tool were well inhibited at the highest rotational speed.For the tool of standard clinical size(diameter 1.25 mm),the maximum force is 0.75 N,with a maximum temperature rise in the operation area of 1.09℃.Debris distribution followed a normal distribution pattern,with 90%of debris measuring smaller than 9.12μm.All tool metrics met clinical safety requirements,indicating its superior performance.This study provides a new idea for the design of calcified tissue removal tools,and contributes positively to the advancement of RA.展开更多
Rotational atherectomy is an effective treatment for severe vascular calcification obstruction,and relies on high-speed grinding(typically 130,000–210,000 r/min)with miniature grinding tools to remove calcified tissu...Rotational atherectomy is an effective treatment for severe vascular calcification obstruction,and relies on high-speed grinding(typically 130,000–210,000 r/min)with miniature grinding tools to remove calcified tissue and restore blood flow.However,reports of intraoperative complications are common because of the grinding force,temperature,and debris directly acting on the body during the grinding process,which can easily cause damage to patients.In this study,three novel grinding tools were designed and fabricated and a series of experiments have been conducted to analyze the effects of tool geometry and parameters on grinding performance,that is,force,temperature,and specimen surface morphology.The results show that these tools can effectively remove simulated calcified tissue and that they have two motions,rotation and revolution,in the tube.At higher rotational speeds,grinding force and temperature increase noticeably,while the amount of debris decreases significantly.In addition,by observing the surface morphology of the specimens,we concluded that the material removal rate per unit time is influenced by both rotational speed and tool geometry,and that high rotational speed and a rough tool surface can improve the material removal rate efficiently.展开更多
Chronic sleep deficiency, a public health epidemic, triggers an elevated risk for physical and mental disorders and may cause unpleasant sensations or experiences in daily life. Importantly, sleep-associated skin dise...Chronic sleep deficiency, a public health epidemic, triggers an elevated risk for physical and mental disorders and may cause unpleasant sensations or experiences in daily life. Importantly, sleep-associated skin diseases attract public attention because most people have anxiety about their facial appearance in modern society. Amounts of health food, especially derived from edible and efficient plant extracts, have been developed for skincare via improvement of sleep quality. Mechanisms of good sleep and healthy skin have been studied, however, the relationship between sleep-promoting herbs and skincare is less elucidated. In this review, we summarize the main signaling pathways of neurotransmitter-mediated skin beauty and list dozens of functional plant extracts for sleep assistance. We conclude several plant candidates for oral cosmetics application through sleep-related neurotransmitters regulation. This review provides pieces of evidence for the application of oral cosmetic food derived from plant extracts in sleep-related beauty.展开更多
文摘The mining height of a coal seam is a critical factor influencing the detachment,collapse,and formation of the collapse angle of the strata during strata movement.To clarify the mechanism by which mining height affects strata movement characteristics,a physical model experiment was conducted based on the geological conditions of the Panel 122104 in Caojiatan Coal Mine in Shaanxi.The experiment examined strata movement at mining heights of 1 m and 10 m,identifying differences in detachment,collapse behavior,and collapse angles under these two conditions.The results indicate the following:Delamination range directly governs collapse patterns,with higher stress concentration accelerating delamination initiation and expanding affected zones.1 m mining height exhibits a“superposed fixed beam”structure with lower strength compared to the“fixed beam+cantilever beam”configuration under 10 m height.A model estimating collapse step shows 9.13%average error.Strata structure dictates collapse angle mechanisms:Pseudo-plastic deformation under 1 m height determines collapse angle through vertical tensile stress boundaries,whereas 10 m height exhibits brittle fracture behavior with collapse angles approximating fracture angles.Periodic collapse volume above working face directly correlates with mine pressure intensity and is positively correlated with the caving step distance,collapse angle,and caving range.These parameters show higher values under 10 m mining height,resulting in more pronounced mine pressure manifestations compared to 1 m conditions.
基金Supported by National Natural Science Foundation of China(Grant No.52205455)Fujian Provincial Health Technology Project(Grant Nos.2022CXA005,2022CXA015)。
文摘Cardiovascular disease is the leading cause of human mortality,and calcified tissue blocking blood vessels is the main cause of major adverse cardiovascular events(MACE).Rotational Atherectomy(RA)is a minimally invasive catheterbased treatment method that involves high-speed cutting of calcified tissue using miniature tools for removal.However,the cutting forces,heat,and debris can induce tissue damage and give rise to serious surgical complications.To enhance the effectiveness and efficiency of RA,a novel eccentric rotational cutting tool,with one side comprising axial and circumferential staggered micro-blades,was designed and fabricated in this study.In addition,a series of experiments were conducted to analyze their performance across five dimensions:tool kinematics,force,temperature,debris,and surface morphology of the specimens.Experimental results show that the force,temperature and debris size of the novel tool were well inhibited at the highest rotational speed.For the tool of standard clinical size(diameter 1.25 mm),the maximum force is 0.75 N,with a maximum temperature rise in the operation area of 1.09℃.Debris distribution followed a normal distribution pattern,with 90%of debris measuring smaller than 9.12μm.All tool metrics met clinical safety requirements,indicating its superior performance.This study provides a new idea for the design of calcified tissue removal tools,and contributes positively to the advancement of RA.
基金supported by the National Natural Science Foundation of China(No.52205455)the Natural and Science Foundation of Fujian Province(No.2021J01560)+1 种基金the Education and Scientific Research Foundation for Young Teachers in Fujian Province(No.JAT190006)the Foreign Cooperation Project from Natural Science Foundation of Fujian Province of China(No.2020I0028).
文摘Rotational atherectomy is an effective treatment for severe vascular calcification obstruction,and relies on high-speed grinding(typically 130,000–210,000 r/min)with miniature grinding tools to remove calcified tissue and restore blood flow.However,reports of intraoperative complications are common because of the grinding force,temperature,and debris directly acting on the body during the grinding process,which can easily cause damage to patients.In this study,three novel grinding tools were designed and fabricated and a series of experiments have been conducted to analyze the effects of tool geometry and parameters on grinding performance,that is,force,temperature,and specimen surface morphology.The results show that these tools can effectively remove simulated calcified tissue and that they have two motions,rotation and revolution,in the tube.At higher rotational speeds,grinding force and temperature increase noticeably,while the amount of debris decreases significantly.In addition,by observing the surface morphology of the specimens,we concluded that the material removal rate per unit time is influenced by both rotational speed and tool geometry,and that high rotational speed and a rough tool surface can improve the material removal rate efficiently.
基金supported by the Key Research and Development Plan of Yunnan Province-Science and Technology Project(2017IB007)the independent research fund of Yunnan Characteristic Plant Extraction Laboratory(2022YKZY005).
文摘Chronic sleep deficiency, a public health epidemic, triggers an elevated risk for physical and mental disorders and may cause unpleasant sensations or experiences in daily life. Importantly, sleep-associated skin diseases attract public attention because most people have anxiety about their facial appearance in modern society. Amounts of health food, especially derived from edible and efficient plant extracts, have been developed for skincare via improvement of sleep quality. Mechanisms of good sleep and healthy skin have been studied, however, the relationship between sleep-promoting herbs and skincare is less elucidated. In this review, we summarize the main signaling pathways of neurotransmitter-mediated skin beauty and list dozens of functional plant extracts for sleep assistance. We conclude several plant candidates for oral cosmetics application through sleep-related neurotransmitters regulation. This review provides pieces of evidence for the application of oral cosmetic food derived from plant extracts in sleep-related beauty.
