As a primary slope stabilization technique,anchor support encompasses traditional engineering anchors,green anchors,and ecological restoration methods.This review synthesizes two decades of literature to evaluate thes...As a primary slope stabilization technique,anchor support encompasses traditional engineering anchors,green anchors,and ecological restoration methods.This review synthesizes two decades of literature to evaluate these approaches.Current research disproportionately focuses on engineering anchors,while green anchor systems remain less studied despite their dual advantages:reduced labor/economic costs and environmental benefits.Notably,most green anchor studies originate from low-altitude plains,with minimal attention to high-altitude cold-arid regions such as plateaus.We therefore identify slope reinforcement using green anchors in plateau environments as a critical emerging research frontier.展开更多
This paper aims to assess the influence of moisture content changes during rainfall on the stability of loess high-fill slopes by taking a loess high-fill slope in Lanzhou City as an example.First,according to the moi...This paper aims to assess the influence of moisture content changes during rainfall on the stability of loess high-fill slopes by taking a loess high-fill slope in Lanzhou City as an example.First,according to the moisture content monitoring data collected from a slope online monitoring system,direct shear tests were performed on soil samples of different moisture content to determine the relationship between the shear strength parameters and moisture content.Next,a coupled hydro-mechanical model with soil shear strength related to moisture content was established and used to analyze 16 working conditions with various rainfall intensities and durations for two cases:shear strength parameters from the site exploration report and those from this study.Finally,the results from the two cases were compared regarding the changes in stresses and displacements after rainfall infiltration to analyze the influence of moisture content on the stability of loess high-fill slopes.The conclusions are as follows:(1)Segmental relationship equations of cohesion and angle of internal friction were established for loess with various moisture content.(2)Under the conditions of different rainfall intensities,significant differences were observed in the trends of slope stress and displacement changes.(3)The slope displacement occurred in the shallow soil layer within about 12.5 m from the slope top,and the plastic strain concentrated in the soil layer within about 6 m from the slope top.(4)The results of slope stability analyses based on moisture content monitoring data are more in line with the observed.展开更多
This paper focuses on the Qinghai-Xizang Plateau.It systematically reviews its seismic activity characteristics and extensive environmental effects under extreme climatic conditions in dry and cold seasons.Firstly,thr...This paper focuses on the Qinghai-Xizang Plateau.It systematically reviews its seismic activity characteristics and extensive environmental effects under extreme climatic conditions in dry and cold seasons.Firstly,through detailed data analysis and literature review,it is revealed how the seasonal significant rainfall and temperature changes in the plateau establish potential links with key parameters such as the frequency and intensity of seismic activity.This process deeply analyzes how natural conditions such as extreme rainfall and temperature changes directly or indirectly affect the mechanism of earthquake preparation and triggering,which may promote or inhibit the occurrence of seismic activity.The close relationship between cold and dry seasons and seismic activity is emphasized,and the unique influence of these special climatic conditions on seismic activity patterns is discussed.In addition,the regional distribution characteristics of seismic activity in the plateau area are also analyzed,including key data such as annual occurrence number and magnitude distribution,which provides strong data support for formulating regional earthquake disaster response strategies.In addition,the characteristics of various secondary disasters that may be caused by earthquakes,such as landslides,debris flows,barrier lakes,etc.,are analyzed,which deepens the understanding of the complexity of the earthquake disaster chain.The aim is to provide a scientific basis for future earthquake disaster prevention and control work and to promote the improvement of earthquake science research and disaster management levels in the Qingzang Plateau and even the world.展开更多
The present study investigated the effects of Fujian tablet, a Chinese medicine compound that can nourish liver and kidney, on corticospinal tract plasticity and cervical cord microenvironment in rats with focal cereb...The present study investigated the effects of Fujian tablet, a Chinese medicine compound that can nourish liver and kidney, on corticospinal tract plasticity and cervical cord microenvironment in rats with focal cerebral ischemia. Results showed that motor function of rats with right proximal middle cerebral artery occlusion was significantly improved following treatment with Fujian tablet, 9 g crude drug/kg. Anterograde tracing revealed significantly increased biotinylated dextran amine expression in the denervated (left) side of the cervical cord (C4-6) following Fujian tablet treatment, and significantly decreased Nogo-A mRNA expression was detected in the denervated side of the cervical cord (C4-6) using in situ hybridization. Pearson's correlation analysis showed a negative correlation between biotinylated dextran amine and Nogo-A mRNA expression (r = -0.943, P 〈 0.01). Results demonstrated that Fujian tablet can promote corticospinal tract plasticity possibly through the inhibitory effect on Nogo-A mRNA expression in the cervical spinal cord, thereby improving motor dysfunction.展开更多
OBJECTIVE: To explore the nature of "Yin internal heat caused by Yin-deficiency" in terms of the theo- ry of Traditional Chinese Medicine, by studying en- ergy metabolism in rats with Yin-deficiency-heat syndrome a...OBJECTIVE: To explore the nature of "Yin internal heat caused by Yin-deficiency" in terms of the theo- ry of Traditional Chinese Medicine, by studying en- ergy metabolism in rats with Yin-deficiency-heat syndrome and analyzing the gene expression pro- file of their livers. METHODS: A Yin-deficiency-heat syndrome model was induced in rats using three Chinese medicinal herbs. Glycogen and triglycerides in blood plasma, and the enzyme activity of ATP in livers were mea- sured colorimetrically. Triiodothyronine (T3), thyrox- ine (T4), and thyroid stimulating hormone levels in blood plasma were also measured with enzyme linked immunosorbent assay. The gene expression profile of livers was detected with gene chip analy- sis. Differentially expressed genes were screened out and classified according to Gene Ontology. The accuracy of results were examined with reversetranscription-polymerase chain reaction RESULTS: Compared with the control group, body weight (P〈0.05) and hepatic glycogen (P〈0.05) were significantly lower in the Yin-deficiency-heat syndrome group. Moreover, toe temperature (P〈 0.01) and triglyceride (P〈0.05), Na +-K+-ATPase (P〈 0.01), Mg2+-ATPase (P〈0.01), T3 (P〈0.05), and 1-4 (P〈 0.01) levels were significantly higher. There were 99 differentially expressed genes in livers from the Y/n-deficiency-heat syndrome group. Genes were mainly related to sterol synthesis (Pc=0.0392), de- fense response (Pc=0.0448), and sterol metabolism (Pc=0.0533). CONCLUSION: Abnormal expression genes in rats with Yin-deficiency-heat syndrome prompted the synthesis and metabolism of cholesterol, increased energy consumption, and reduced defense re- sponse. This gene expression might be the molecu- lar mechanism underlying "internal heat caused by Yin-deficiency" in the rats with Yin-deficiency-heat syndrome.展开更多
To clarify the changes in slope stability of loess slopes under the coupling action of rainfall and vehicle loads.Experiments with different water contents under different environmental conditions were carried out ind...To clarify the changes in slope stability of loess slopes under the coupling action of rainfall and vehicle loads.Experiments with different water contents under different environmental conditions were carried out indoors,and the relationship function between water content and shear strength parameters was obtained;based on Geostudio,an equivalent layered calculation model of water content-strength parameters of loess slope was established,the variation law of soil sample matrix suction with volumetric water content was measured by volumetric pressure plate tester.Finally,by using a combination of finite element analysis of saturated/unsatu-rated seepage and limit equilibrium analysis of slope stability,the SLOPE/W module in the modeling software GeoStudio is used to calculate and analyze the effects of vehicle loads,rainfall intensity,rainfall duration,and other working conditions on the stability of loess slopes,respectively.The results show that when the lane is in the middle of the slope,the vehicle load parameters have little effect on the uphill stability,but have a greater impact on the downhill;With the increase in rainfall,the change curves of the slope safety coefficient gradually overlap when the vehicle loads are four-axis,five-axis,and six-axis.This shows that when studying the change of slope safety factor under the dual influence of vehicle loads and rainfall,rainfall is the main cause of slope stability;The change rate of slope safety factor increases gradually with the increase of rainfall,and the change trends of the upper,lower and overall parts of the slope are similar.展开更多
This study aims to utilize the Small Baseline Subset Interferometric Synthetic Aperture Radar(SBAS-In SAR)technique and Google Earth optical remote sensing images to analyze the area within 20 km around the epicenter ...This study aims to utilize the Small Baseline Subset Interferometric Synthetic Aperture Radar(SBAS-In SAR)technique and Google Earth optical remote sensing images to analyze the area within 20 km around the epicenter of a M 3.9, earthquake that occurred in Tanchang County, Gansu Province, on December 28, 2020. The objective is to identify potential earthquake-induced landslides, assess their scale, and determine their impact range. The study results reveal the successful identification of two potential landslides in the 20 km radius around the epicenter. Through time-series deformation analysis, it was observed that these potential landslides were significantly influenced by both the earthquake and rainfall. Further estimation of these potential landslides indicates maximum depths of 7.4 m and 14.1 m for the failure surfaces, with volumes of 9.02 × 10~4m~3and 25.5 ×10~4m~3, respectively. Finally, based on the simulation analysis of Massflow software, the maximum thickness of soil accumulation in the final accumulation area after sliding of the potential landslide in Shangyaai is 12 m, the area of the final accumulation area is 1.75 × 10~4m~2, and the farthest movement distance is 1124 m. The maximum thickness of soil accumulation in the final accumulation area after sliding of the potential landslide in Wangshancun is 8 m, the area of the final accumulation area is 7.89 × 10~4m~2, and the farthest movement distance is 742 m.展开更多
Microseismic source localization plays a critical role in monitoring mining-induced dynamic disasters,assessing rock mass stability,and analyzing excavation-induced disturbances.With increasing monitoring accuracy and...Microseismic source localization plays a critical role in monitoring mining-induced dynamic disasters,assessing rock mass stability,and analyzing excavation-induced disturbances.With increasing monitoring accuracy and data volume,various localization techniques have emerged to suit different scenarios.We systematically review the development of current microseismic location methods,which can be broadly categorized into three types:(1)Pickingbased methods,such as the Geiger and double-difference algorithms,which are suitable for well-constrained velocity models;(2)Waveform stacking-based localization methods,such as the source scanning algorithm(SSA)and cross-correlation stacking,which eliminate the need for arrival-time picking.These techniques exhibit strong noise resistance and are particularly well-suited for environments with low signal-to-noise ratios(SNR);and(3)Deep learning-based automatic localization approaches,such as PhaseNet and LOCFLOW,which are suitable for large-scale,intelligent monitoring.Furthermore,key factors affecting localization accuracy,such as sensor array geometry,arrival-time picking errors,and velocity model uncertainties,are discussed,along with optimization strategies including 3D velocity tomography,non-predefined velocity inversion,and time-varying velocity modeling.Finally,we explore future directions,including multi-station collaborative deep learning models,intelligent denoising techniques,and risk prediction frameworks constrained by statistical seismology,aiming to advance microseismic localization toward higher precision and robustness.展开更多
基金supported by a grant from the National Natural Science Foundation of China(42461020)the Gansu Province joint research Fund project(24JRRA799 and 24JRRA857)。
文摘As a primary slope stabilization technique,anchor support encompasses traditional engineering anchors,green anchors,and ecological restoration methods.This review synthesizes two decades of literature to evaluate these approaches.Current research disproportionately focuses on engineering anchors,while green anchor systems remain less studied despite their dual advantages:reduced labor/economic costs and environmental benefits.Notably,most green anchor studies originate from low-altitude plains,with minimal attention to high-altitude cold-arid regions such as plateaus.We therefore identify slope reinforcement using green anchors in plateau environments as a critical emerging research frontier.
基金supported by a grant from the Gansu Provincial Department of Natural Resources Science and Technology Innovation Talent Cultivation Project(2022–09)the Geological Disaster Prevention Projects of the Gansu Provincial Bureau of Geology and Mineral Resources,and Natural Science Foundation of Gansu Province(No.22JR5RA326).
文摘This paper aims to assess the influence of moisture content changes during rainfall on the stability of loess high-fill slopes by taking a loess high-fill slope in Lanzhou City as an example.First,according to the moisture content monitoring data collected from a slope online monitoring system,direct shear tests were performed on soil samples of different moisture content to determine the relationship between the shear strength parameters and moisture content.Next,a coupled hydro-mechanical model with soil shear strength related to moisture content was established and used to analyze 16 working conditions with various rainfall intensities and durations for two cases:shear strength parameters from the site exploration report and those from this study.Finally,the results from the two cases were compared regarding the changes in stresses and displacements after rainfall infiltration to analyze the influence of moisture content on the stability of loess high-fill slopes.The conclusions are as follows:(1)Segmental relationship equations of cohesion and angle of internal friction were established for loess with various moisture content.(2)Under the conditions of different rainfall intensities,significant differences were observed in the trends of slope stress and displacement changes.(3)The slope displacement occurred in the shallow soil layer within about 12.5 m from the slope top,and the plastic strain concentrated in the soil layer within about 6 m from the slope top.(4)The results of slope stability analyses based on moisture content monitoring data are more in line with the observed.
基金supported by the National Natural Science Foundation of China (42461020)Gansu Province joint research fund project (24JRRA857,24JRRA847,24JRRA799).
文摘This paper focuses on the Qinghai-Xizang Plateau.It systematically reviews its seismic activity characteristics and extensive environmental effects under extreme climatic conditions in dry and cold seasons.Firstly,through detailed data analysis and literature review,it is revealed how the seasonal significant rainfall and temperature changes in the plateau establish potential links with key parameters such as the frequency and intensity of seismic activity.This process deeply analyzes how natural conditions such as extreme rainfall and temperature changes directly or indirectly affect the mechanism of earthquake preparation and triggering,which may promote or inhibit the occurrence of seismic activity.The close relationship between cold and dry seasons and seismic activity is emphasized,and the unique influence of these special climatic conditions on seismic activity patterns is discussed.In addition,the regional distribution characteristics of seismic activity in the plateau area are also analyzed,including key data such as annual occurrence number and magnitude distribution,which provides strong data support for formulating regional earthquake disaster response strategies.In addition,the characteristics of various secondary disasters that may be caused by earthquakes,such as landslides,debris flows,barrier lakes,etc.,are analyzed,which deepens the understanding of the complexity of the earthquake disaster chain.The aim is to provide a scientific basis for future earthquake disaster prevention and control work and to promote the improvement of earthquake science research and disaster management levels in the Qingzang Plateau and even the world.
基金the National Natural Science Foundation of China, No. 30801470
文摘The present study investigated the effects of Fujian tablet, a Chinese medicine compound that can nourish liver and kidney, on corticospinal tract plasticity and cervical cord microenvironment in rats with focal cerebral ischemia. Results showed that motor function of rats with right proximal middle cerebral artery occlusion was significantly improved following treatment with Fujian tablet, 9 g crude drug/kg. Anterograde tracing revealed significantly increased biotinylated dextran amine expression in the denervated (left) side of the cervical cord (C4-6) following Fujian tablet treatment, and significantly decreased Nogo-A mRNA expression was detected in the denervated side of the cervical cord (C4-6) using in situ hybridization. Pearson's correlation analysis showed a negative correlation between biotinylated dextran amine and Nogo-A mRNA expression (r = -0.943, P 〈 0.01). Results demonstrated that Fujian tablet can promote corticospinal tract plasticity possibly through the inhibitory effect on Nogo-A mRNA expression in the cervical spinal cord, thereby improving motor dysfunction.
基金Supported by the National Basic Research Program of China(973 Program,No.2007CB512601,2013CB531803)
文摘OBJECTIVE: To explore the nature of "Yin internal heat caused by Yin-deficiency" in terms of the theo- ry of Traditional Chinese Medicine, by studying en- ergy metabolism in rats with Yin-deficiency-heat syndrome and analyzing the gene expression pro- file of their livers. METHODS: A Yin-deficiency-heat syndrome model was induced in rats using three Chinese medicinal herbs. Glycogen and triglycerides in blood plasma, and the enzyme activity of ATP in livers were mea- sured colorimetrically. Triiodothyronine (T3), thyrox- ine (T4), and thyroid stimulating hormone levels in blood plasma were also measured with enzyme linked immunosorbent assay. The gene expression profile of livers was detected with gene chip analy- sis. Differentially expressed genes were screened out and classified according to Gene Ontology. The accuracy of results were examined with reversetranscription-polymerase chain reaction RESULTS: Compared with the control group, body weight (P〈0.05) and hepatic glycogen (P〈0.05) were significantly lower in the Yin-deficiency-heat syndrome group. Moreover, toe temperature (P〈 0.01) and triglyceride (P〈0.05), Na +-K+-ATPase (P〈 0.01), Mg2+-ATPase (P〈0.01), T3 (P〈0.05), and 1-4 (P〈 0.01) levels were significantly higher. There were 99 differentially expressed genes in livers from the Y/n-deficiency-heat syndrome group. Genes were mainly related to sterol synthesis (Pc=0.0392), de- fense response (Pc=0.0448), and sterol metabolism (Pc=0.0533). CONCLUSION: Abnormal expression genes in rats with Yin-deficiency-heat syndrome prompted the synthesis and metabolism of cholesterol, increased energy consumption, and reduced defense re- sponse. This gene expression might be the molecu- lar mechanism underlying "internal heat caused by Yin-deficiency" in the rats with Yin-deficiency-heat syndrome.
基金the support and motivation provided by the National Natural Science Foundation of China (No.41501062)the Longyuan Youth Innovation and Entrepreneurship Talent (Team) Project of Gansu Province,Chinathe Natural Science Foundation of Gansu Province,China (No.20JR10RA227).
文摘To clarify the changes in slope stability of loess slopes under the coupling action of rainfall and vehicle loads.Experiments with different water contents under different environmental conditions were carried out indoors,and the relationship function between water content and shear strength parameters was obtained;based on Geostudio,an equivalent layered calculation model of water content-strength parameters of loess slope was established,the variation law of soil sample matrix suction with volumetric water content was measured by volumetric pressure plate tester.Finally,by using a combination of finite element analysis of saturated/unsatu-rated seepage and limit equilibrium analysis of slope stability,the SLOPE/W module in the modeling software GeoStudio is used to calculate and analyze the effects of vehicle loads,rainfall intensity,rainfall duration,and other working conditions on the stability of loess slopes,respectively.The results show that when the lane is in the middle of the slope,the vehicle load parameters have little effect on the uphill stability,but have a greater impact on the downhill;With the increase in rainfall,the change curves of the slope safety coefficient gradually overlap when the vehicle loads are four-axis,five-axis,and six-axis.This shows that when studying the change of slope safety factor under the dual influence of vehicle loads and rainfall,rainfall is the main cause of slope stability;The change rate of slope safety factor increases gradually with the increase of rainfall,and the change trends of the upper,lower and overall parts of the slope are similar.
基金supported by the Natural Science Foundation of Gansu Province (22JR5RA326)The geological disaster prevention projects of Gansu Provincial Bureau of Geology and Mineral Resources (2023-2-9)。
文摘This study aims to utilize the Small Baseline Subset Interferometric Synthetic Aperture Radar(SBAS-In SAR)technique and Google Earth optical remote sensing images to analyze the area within 20 km around the epicenter of a M 3.9, earthquake that occurred in Tanchang County, Gansu Province, on December 28, 2020. The objective is to identify potential earthquake-induced landslides, assess their scale, and determine their impact range. The study results reveal the successful identification of two potential landslides in the 20 km radius around the epicenter. Through time-series deformation analysis, it was observed that these potential landslides were significantly influenced by both the earthquake and rainfall. Further estimation of these potential landslides indicates maximum depths of 7.4 m and 14.1 m for the failure surfaces, with volumes of 9.02 × 10~4m~3and 25.5 ×10~4m~3, respectively. Finally, based on the simulation analysis of Massflow software, the maximum thickness of soil accumulation in the final accumulation area after sliding of the potential landslide in Shangyaai is 12 m, the area of the final accumulation area is 1.75 × 10~4m~2, and the farthest movement distance is 1124 m. The maximum thickness of soil accumulation in the final accumulation area after sliding of the potential landslide in Wangshancun is 8 m, the area of the final accumulation area is 7.89 × 10~4m~2, and the farthest movement distance is 742 m.
基金funded by the Deep Earth Probe and Mineral Resources Exploration-National Science and Technology Major Project(2024ZD1004505)Gansu Provincial Joint Research Fund for the Year 2024(24JRRA803)+1 种基金Guangdong Provincial Key Laboratory of Geophysical High-resolution Imaging Technology(2022B1212010002)the National Natural Science Foundation of China(42174128).
文摘Microseismic source localization plays a critical role in monitoring mining-induced dynamic disasters,assessing rock mass stability,and analyzing excavation-induced disturbances.With increasing monitoring accuracy and data volume,various localization techniques have emerged to suit different scenarios.We systematically review the development of current microseismic location methods,which can be broadly categorized into three types:(1)Pickingbased methods,such as the Geiger and double-difference algorithms,which are suitable for well-constrained velocity models;(2)Waveform stacking-based localization methods,such as the source scanning algorithm(SSA)and cross-correlation stacking,which eliminate the need for arrival-time picking.These techniques exhibit strong noise resistance and are particularly well-suited for environments with low signal-to-noise ratios(SNR);and(3)Deep learning-based automatic localization approaches,such as PhaseNet and LOCFLOW,which are suitable for large-scale,intelligent monitoring.Furthermore,key factors affecting localization accuracy,such as sensor array geometry,arrival-time picking errors,and velocity model uncertainties,are discussed,along with optimization strategies including 3D velocity tomography,non-predefined velocity inversion,and time-varying velocity modeling.Finally,we explore future directions,including multi-station collaborative deep learning models,intelligent denoising techniques,and risk prediction frameworks constrained by statistical seismology,aiming to advance microseismic localization toward higher precision and robustness.