The convergence of large language models(LLMs)and virtual reality(VR)technologies has led to significant breakthroughs across multiple domains,particularly in healthcare and medicine.Owing to its immersive and interac...The convergence of large language models(LLMs)and virtual reality(VR)technologies has led to significant breakthroughs across multiple domains,particularly in healthcare and medicine.Owing to its immersive and interactive capabilities,VR technology has demonstrated exceptional utility in surgical simulation,rehabilitation,physical therapy,mental health,and psychological treatment.By creating highly realistic and precisely controlled environments,VR not only enhances the efficiency of medical training but also enables personalized therapeutic approaches for patients.The convergence of LLMs and VR extends the potential of both technologies.LLM-empowered VR can transform medical education through interactive learning platforms and address complex healthcare challenges using comprehensive solutions.This convergence enhances the quality of training,decision-making,and patient engagement,paving the way for innovative healthcare delivery.This study aims to comprehensively review the current applications,research advancements,and challenges associated with these two technologies in healthcare and medicine.The rapid evolution of these technologies is driving the healthcare industry toward greater intelligence and precision,establishing them as critical forces in the transformation of modern medicine.展开更多
To support mission-critical applications, such as factory automation and autonomous driving, the ultra-reliable low latency communications (URLLC) is adopted in the fifth generation (5G) mobile communications network,...To support mission-critical applications, such as factory automation and autonomous driving, the ultra-reliable low latency communications (URLLC) is adopted in the fifth generation (5G) mobile communications network, which requires high level of reliability and low latency. Naturally, URLLC in the future 6G is expected to have a better capability than its 5G version which poses an unprecedented challenge to us. Fortunately, the potential solution can still be found in the well-known classical Shannon information theory. Since the latency constraint can be represented equivalently by blocklength, channel coding at finite blocklength plays an important role in the theoretic analysis of URLLC. Applying these achievements in rapidly development of massive MIMO techniques gives rise to a new theory on space time exchanging. It tells us that channel coding can also be performed in space domain, since it is capable of providing the same coding rate as that in time domain. This space time exchanging theory points out an exciting and feasible direction for us to further reduce latency in 6G URLLC. .展开更多
Objective: To evaluate the effect of salidroside on oxygen and glucose deprivation(OGD)-treated NT2 cells and its underlying mechanisms of action.Methods: Retinoic acid was used to induce the differentiation of NT2 ce...Objective: To evaluate the effect of salidroside on oxygen and glucose deprivation(OGD)-treated NT2 cells and its underlying mechanisms of action.Methods: Retinoic acid was used to induce the differentiation of NT2 cells into neurons. The effects of salidroside on survival, apoptosis, inflammatory response, and oxidative stress of neurons undergoing OGD were evaluated. Using precursor cells as controls, the effect of salidroside on the differentiation progression of OGDtreated cells was evaluated. In addition, the effect of erastin, a ferroptosis inducer, on NT2 cells was examined to investigate the underlying mechanisms of neuroprotective action of salidroside.Results: Salidroside alleviated the effects of OGD on neuronal survival, apoptosis, inflammation, and oxidative stress, and promoted NT2 cell differentiation. Moreover, salidroside prevented ferroptosis of OGD-treated cells, which was abolished following erastin treatment, indicating that ferroptosis mediated the regulatory pathway of salidroside.Conclusions: Salidroside attenuates OGD-induced neuronal injury by inhibiting ferroptosis and promotes neuronal differentiation.展开更多
Background Hand ge stur e interfaces are dedicated programs that principally perform hand tracking and hand gesture prediction to provide alternative controls and interaction methods.They take advantage of one of the ...Background Hand ge stur e interfaces are dedicated programs that principally perform hand tracking and hand gesture prediction to provide alternative controls and interaction methods.They take advantage of one of the most natural ways of interaction and communication,proposing novel input and showing great potential in the field of the human-computer interaction.Developing a flexible and rich hand gesture interface is known to be a time-consuming and arduous task.Previously published studies have demonstrated the significance of the finite-state-machine(FSM)approach when mapping detected gestures to GUI actions.Methods In our hand gesture interface,we broadened the FSM approach by utilizing gesture-specific attributes,such as distance between hands,distance from the camera,and time of occurrences,to enable users to perform unique GUI actions.These attributes are obtained from hand gestures detected by the RealSense SDK employed in our hand gesture interface.By means of these gesture-specific attributes,users can activate static gestures and perform them as dynamic gestures.We also provided supplementary features to enhance the efficiency,convenience,and user-friendliness of our hand gesture interface.Moreover,we developed a complementary application for recording hand gestures by capturing hand keypoints in depth and color images to facilitate the generation of hand gesture datasets.Results We conducted a small-scale user survey with fifteen subjects to test and evaluate our hand gesture interface.Anonymous feedback obtained from the users indicates that our hand gesture interface is adequately facile and self-explanatory to use.In addition,we received constructive feedback about minor flaws regarding the responsiveness of the interface.Conclusions We proposed a hand gesture interface along with key concepts to attain use r-friendlines s and effectiveness in the control of existing GUIs.展开更多
基金Supported by Noncommunicable Chronic Diseases-National Science and Technology Major Project(2024ZD0523200)National Natural Science Foundation of China(62301330,62101346).
文摘The convergence of large language models(LLMs)and virtual reality(VR)technologies has led to significant breakthroughs across multiple domains,particularly in healthcare and medicine.Owing to its immersive and interactive capabilities,VR technology has demonstrated exceptional utility in surgical simulation,rehabilitation,physical therapy,mental health,and psychological treatment.By creating highly realistic and precisely controlled environments,VR not only enhances the efficiency of medical training but also enables personalized therapeutic approaches for patients.The convergence of LLMs and VR extends the potential of both technologies.LLM-empowered VR can transform medical education through interactive learning platforms and address complex healthcare challenges using comprehensive solutions.This convergence enhances the quality of training,decision-making,and patient engagement,paving the way for innovative healthcare delivery.This study aims to comprehensively review the current applications,research advancements,and challenges associated with these two technologies in healthcare and medicine.The rapid evolution of these technologies is driving the healthcare industry toward greater intelligence and precision,establishing them as critical forces in the transformation of modern medicine.
文摘To support mission-critical applications, such as factory automation and autonomous driving, the ultra-reliable low latency communications (URLLC) is adopted in the fifth generation (5G) mobile communications network, which requires high level of reliability and low latency. Naturally, URLLC in the future 6G is expected to have a better capability than its 5G version which poses an unprecedented challenge to us. Fortunately, the potential solution can still be found in the well-known classical Shannon information theory. Since the latency constraint can be represented equivalently by blocklength, channel coding at finite blocklength plays an important role in the theoretic analysis of URLLC. Applying these achievements in rapidly development of massive MIMO techniques gives rise to a new theory on space time exchanging. It tells us that channel coding can also be performed in space domain, since it is capable of providing the same coding rate as that in time domain. This space time exchanging theory points out an exciting and feasible direction for us to further reduce latency in 6G URLLC. .
基金supported by the Zhejiang Traditional Chinese Medicine Science and Technology Plan Project(2021ZB027,2023ZL267)Zhejiang Medical and Health Platform Project of China(2019KY002,2019RC092).
文摘Objective: To evaluate the effect of salidroside on oxygen and glucose deprivation(OGD)-treated NT2 cells and its underlying mechanisms of action.Methods: Retinoic acid was used to induce the differentiation of NT2 cells into neurons. The effects of salidroside on survival, apoptosis, inflammatory response, and oxidative stress of neurons undergoing OGD were evaluated. Using precursor cells as controls, the effect of salidroside on the differentiation progression of OGDtreated cells was evaluated. In addition, the effect of erastin, a ferroptosis inducer, on NT2 cells was examined to investigate the underlying mechanisms of neuroprotective action of salidroside.Results: Salidroside alleviated the effects of OGD on neuronal survival, apoptosis, inflammation, and oxidative stress, and promoted NT2 cell differentiation. Moreover, salidroside prevented ferroptosis of OGD-treated cells, which was abolished following erastin treatment, indicating that ferroptosis mediated the regulatory pathway of salidroside.Conclusions: Salidroside attenuates OGD-induced neuronal injury by inhibiting ferroptosis and promotes neuronal differentiation.
文摘Background Hand ge stur e interfaces are dedicated programs that principally perform hand tracking and hand gesture prediction to provide alternative controls and interaction methods.They take advantage of one of the most natural ways of interaction and communication,proposing novel input and showing great potential in the field of the human-computer interaction.Developing a flexible and rich hand gesture interface is known to be a time-consuming and arduous task.Previously published studies have demonstrated the significance of the finite-state-machine(FSM)approach when mapping detected gestures to GUI actions.Methods In our hand gesture interface,we broadened the FSM approach by utilizing gesture-specific attributes,such as distance between hands,distance from the camera,and time of occurrences,to enable users to perform unique GUI actions.These attributes are obtained from hand gestures detected by the RealSense SDK employed in our hand gesture interface.By means of these gesture-specific attributes,users can activate static gestures and perform them as dynamic gestures.We also provided supplementary features to enhance the efficiency,convenience,and user-friendliness of our hand gesture interface.Moreover,we developed a complementary application for recording hand gestures by capturing hand keypoints in depth and color images to facilitate the generation of hand gesture datasets.Results We conducted a small-scale user survey with fifteen subjects to test and evaluate our hand gesture interface.Anonymous feedback obtained from the users indicates that our hand gesture interface is adequately facile and self-explanatory to use.In addition,we received constructive feedback about minor flaws regarding the responsiveness of the interface.Conclusions We proposed a hand gesture interface along with key concepts to attain use r-friendlines s and effectiveness in the control of existing GUIs.
