OBJECTIVE:To observe the effects of acupuncture on motility of jejunum and distal colon at different acupoints on normal Kunming mice.METHODS:The jejunal and colorectal motor activity of forty Kunming mice were record...OBJECTIVE:To observe the effects of acupuncture on motility of jejunum and distal colon at different acupoints on normal Kunming mice.METHODS:The jejunal and colorectal motor activity of forty Kunming mice were recorded by the intra-intestinal capsule.The capsules contained with distilled water were placed into the cavities of jejunum and distal colon.The changes of bowel were compared with the background activity recorded before any stimulation.The chosen acupoints were as follows:Zusanli(ST 36) on the lower legs,Tianshu(ST 25) on the mid-lower abdomen.RESULTS:Manual acupuncture(MA) at Zusanli(ST36) significantly promoted the motility of jejunum and distal colon(manifested as increased change rate of average amplitude and increased change rate of mean area under the contractile curve) of normal Kunming mice(P < 0.01).MA atTianshu(ST25) significantly inhibited the motility of jejunum(manifested as decreased change rate of average amplitude,decreased change rate of mean area under the contractile curve,and the reduced frequency) of normal Kunming mice(P < 0.01),while significantly increased the distal colonic motility(manifested as increased amplitude and increased mean area under the contractile curve) of normal Kunming mice(P < 0.01).CONCLUSION:MA at specific acupoints[Zusanli(ST 36),Tianshu(ST 25)]has different effects on the motility of jejunum and distal colon,which might involve the segmental innervations of the related nerve.展开更多
I am the manager of the Sheffield City Council’s Chinese project. This time I came to attend the business matching activities of the 2019 China Industrial and Commercial Enterprises Cross-border Investment and Trade ...I am the manager of the Sheffield City Council’s Chinese project. This time I came to attend the business matching activities of the 2019 China Industrial and Commercial Enterprises Cross-border Investment and Trade event. I read the February issue of China Today with the special report on the 13th Confucius Institute Conference. Professor Sir Keith Burnett – former president and vice chancellor of the University of Sheffield-is our old friend. We agree with his views in the article “The Bridge between China and the U.K.” As he said, besides cooperation with schools that offer Chinese courses, the institute is striving to promote mutual understanding between engineers, scientists, and entrepreneurs in the two countries, and to further deepen the friendship among business partners. That is what the Sheffield City Council has done and would like to push further ahead. China is a hugely important trading partner for the U.K.’s north. We have many longstanding cultural and commercial relationships.展开更多
Acupoints are particular areas on the surface of the body through which the Qi and blood of the Zang-fu organs and meridians flow.Acupoints can respond to stimuli and reflect syndromes.Research on the essential morpho...Acupoints are particular areas on the surface of the body through which the Qi and blood of the Zang-fu organs and meridians flow.Acupoints can respond to stimuli and reflect syndromes.Research on the essential morphology of acupoints has two key focuses:anatomical structure and physiological function.The structure is the material and anatomical basis for the function,while the function is the manifestation of the structure.The two factors not only have profound significance for our understanding of the essence of acupoints,but also have great value for clinical acupuncture and moxibustion practice.Based on the structural and functional characteristics of meridians under different physiological and pathological conditions,this paper illustrates the essence of acupoints and explores the rules and biological basis of the acupoint functions induced by acupuncture and moxibustion.展开更多
Background Previous studies demonstrated that vagus nerve stimulation (VNS) is an effective therapy for drugresistant epilepsy.Acupuncture is also used to treat epilepsy.This study was designed to examine the safety...Background Previous studies demonstrated that vagus nerve stimulation (VNS) is an effective therapy for drugresistant epilepsy.Acupuncture is also used to treat epilepsy.This study was designed to examine the safety and effectiveness of transcutaneous auricular vagus nerve stimulation (ta-VNS) for patients with drug-resistant epilepsy.Methods A total of 50 volunteer patients with drug-resistant epilepsy were selected for a random clinical trial to observe the therapeutic effect of ta-VNS.The seizure frequency,quality of life,and severity were assessed in weeks 8,16,and 24 of the treatment according to the percentage of seizure frequency reduction.Results In the pilot study,47 of the 50 epilepsy patients completed the 24-week treatment; three dropped off.After 8-week treatment,six of the 47 patients (12%) were seizure free and 12 (24%) had a reduction in seizure frequency.In week 16 of the continuous treatment,six of the 47 patients (12%)were seizure free; 17 (34%) had a reduction in seizure frequency.After 24 weeks' treatment,eight patients (16%) were seizure free; 19 (38%) had reduced seizure frequency.Conclusion Similar to the therapeutic effect of VNS,ta-VNS can suppress epileptic seizures and is a safe,effective,economical,and widely applicable treatment option for drug-resistant epilepsy.(ChiCTR-TRC-10001023)展开更多
基金Supported by National Basic Research Program of China:Mechanisms of Dual Effects of Acupuncture on Functional Intestinal Disease(973 Program,No.2011CB505200)the National Natural Science Foundation of China Research Grants:Investigations on Effect of Acupuncture In Functional Bowel Disorders Via CRF Signaling Pathway(No.81202763)
文摘OBJECTIVE:To observe the effects of acupuncture on motility of jejunum and distal colon at different acupoints on normal Kunming mice.METHODS:The jejunal and colorectal motor activity of forty Kunming mice were recorded by the intra-intestinal capsule.The capsules contained with distilled water were placed into the cavities of jejunum and distal colon.The changes of bowel were compared with the background activity recorded before any stimulation.The chosen acupoints were as follows:Zusanli(ST 36) on the lower legs,Tianshu(ST 25) on the mid-lower abdomen.RESULTS:Manual acupuncture(MA) at Zusanli(ST36) significantly promoted the motility of jejunum and distal colon(manifested as increased change rate of average amplitude and increased change rate of mean area under the contractile curve) of normal Kunming mice(P < 0.01).MA atTianshu(ST25) significantly inhibited the motility of jejunum(manifested as decreased change rate of average amplitude,decreased change rate of mean area under the contractile curve,and the reduced frequency) of normal Kunming mice(P < 0.01),while significantly increased the distal colonic motility(manifested as increased amplitude and increased mean area under the contractile curve) of normal Kunming mice(P < 0.01).CONCLUSION:MA at specific acupoints[Zusanli(ST 36),Tianshu(ST 25)]has different effects on the motility of jejunum and distal colon,which might involve the segmental innervations of the related nerve.
文摘I am the manager of the Sheffield City Council’s Chinese project. This time I came to attend the business matching activities of the 2019 China Industrial and Commercial Enterprises Cross-border Investment and Trade event. I read the February issue of China Today with the special report on the 13th Confucius Institute Conference. Professor Sir Keith Burnett – former president and vice chancellor of the University of Sheffield-is our old friend. We agree with his views in the article “The Bridge between China and the U.K.” As he said, besides cooperation with schools that offer Chinese courses, the institute is striving to promote mutual understanding between engineers, scientists, and entrepreneurs in the two countries, and to further deepen the friendship among business partners. That is what the Sheffield City Council has done and would like to push further ahead. China is a hugely important trading partner for the U.K.’s north. We have many longstanding cultural and commercial relationships.
基金supported by the Key Project of National Natural Science Foundation of China(81130063)the 973 Project(2012CB 518503)
文摘Acupoints are particular areas on the surface of the body through which the Qi and blood of the Zang-fu organs and meridians flow.Acupoints can respond to stimuli and reflect syndromes.Research on the essential morphology of acupoints has two key focuses:anatomical structure and physiological function.The structure is the material and anatomical basis for the function,while the function is the manifestation of the structure.The two factors not only have profound significance for our understanding of the essence of acupoints,but also have great value for clinical acupuncture and moxibustion practice.Based on the structural and functional characteristics of meridians under different physiological and pathological conditions,this paper illustrates the essence of acupoints and explores the rules and biological basis of the acupoint functions induced by acupuncture and moxibustion.
基金This scientific study was funded by the General Program of National Natural Science Foundation of China (No. 30973798), the Special Program of Chinese Medicine of the National Basic Research Program of China (973 Program, No. 2012CB518503), National Twelfth Five-year Science and Technology Support Program (No. 2012BAF 14B 10), and the Capital Medical Development Foundation of China (TCM-SF-2009-II- 15).
文摘Background Previous studies demonstrated that vagus nerve stimulation (VNS) is an effective therapy for drugresistant epilepsy.Acupuncture is also used to treat epilepsy.This study was designed to examine the safety and effectiveness of transcutaneous auricular vagus nerve stimulation (ta-VNS) for patients with drug-resistant epilepsy.Methods A total of 50 volunteer patients with drug-resistant epilepsy were selected for a random clinical trial to observe the therapeutic effect of ta-VNS.The seizure frequency,quality of life,and severity were assessed in weeks 8,16,and 24 of the treatment according to the percentage of seizure frequency reduction.Results In the pilot study,47 of the 50 epilepsy patients completed the 24-week treatment; three dropped off.After 8-week treatment,six of the 47 patients (12%) were seizure free and 12 (24%) had a reduction in seizure frequency.In week 16 of the continuous treatment,six of the 47 patients (12%)were seizure free; 17 (34%) had a reduction in seizure frequency.After 24 weeks' treatment,eight patients (16%) were seizure free; 19 (38%) had reduced seizure frequency.Conclusion Similar to the therapeutic effect of VNS,ta-VNS can suppress epileptic seizures and is a safe,effective,economical,and widely applicable treatment option for drug-resistant epilepsy.(ChiCTR-TRC-10001023)