目的探讨膳食炎症指数(dietary inflammatory index,DII)与老年人群脑卒中后衰弱之间的关联,为预防和治疗脑卒中后衰弱提供思路。方法采用横断面研究,基于2011—2018年美国国家健康营养调查(the US National Health and Nutrition Exami...目的探讨膳食炎症指数(dietary inflammatory index,DII)与老年人群脑卒中后衰弱之间的关联,为预防和治疗脑卒中后衰弱提供思路。方法采用横断面研究,基于2011—2018年美国国家健康营养调查(the US National Health and Nutrition Examination Survey,NHANES)老年脑卒中人群数据,依据衰弱指数将研究对象分为对照组和衰弱组,计算DII并收集相关协变量数据。多因素logistic回归被用于分析DII和脑卒中后衰弱的关联性,构建限制性立方样条(restricted cubic spline,RCS)模型以明确DII和脑卒中后衰弱的剂量-反应关系。结果共纳入1340例老年脑卒中患者,检出衰弱患者719例,衰弱发生率为53.66%。总体DII中位数为1.32,衰弱组DII高于对照组,组间差异有统计学意义(Z=-5.719,P<0.001)。logistic回归分析结果表明,在调整所有协变量后,DII升高仍与较高的衰弱发生率显著相关(OR=1.463~1.886,P<0.05),趋势性检验差异有统计学意义(P<0.05)。RCS模型显示DII与老年人群脑卒中后衰弱呈正向线性相关(非线性P=0.376)。结论老年人群脑卒中后衰弱发生率较高,DII与衰弱风险增高相关,制定合理的膳食计划有利于预防衰弱的发生。展开更多
Triisopropanolamine (TIPA) was used as an early strength component to study its effects on mortar strength, cement paste setting time and early hydration characteristic of cement. And the early strength mechanism of T...Triisopropanolamine (TIPA) was used as an early strength component to study its effects on mortar strength, cement paste setting time and early hydration characteristic of cement. And the early strength mechanism of TIPA at low temperature of 5 ℃ was also discussed. The results showed that, at 5 ℃, the incorporation of TIPA promoted the condensation of cement paste, shortened the initial and final setting time, and accelerated the strength development of specimens at all ages, among which the strength after 3 d increased significantly. The 1, 3, 7, and 28 d compressive strength ratios of the mortars mixed with 1% TIPA could reach 196%, 179%, 160% and 110% respectively, and the mortar strength after 3 d exceeded that of the contrast sample cured at 20 ℃. Under low temperature condition, TIPA could promote the hydration reaction of cement, shorten the induction period and advance the acceleration period. Furthermore, the maximum heat release rate and cumulative heat release quantity would be all increased, and the cumulative heat release of the cement mixed with TIPA hydrated for 12 h and 7 d increased 73% and 38% respectively. TIPA could shorten the nucleation and crystal growth (NG) stage and increase its hydration degree significantly, so it promoted cement hydration reaction. Additionally, the hydration reaction rates in phase boundary reaction (I) phase and diffusion reaction (D) phase were increased, and the duration of I process was prolonged, thereby the development of specimen strength would be accelerated. TIPA did not obviously change the types of hydration products, but increased the content of Ca(OH)2 in the samples and the degree of cement hydration. After hydration to 7 d, large amounts of hydration products, whose surface was smooth, were formed and bonded into sheets, and the structural density of samples improved significantly.展开更多
文摘目的探讨膳食炎症指数(dietary inflammatory index,DII)与老年人群脑卒中后衰弱之间的关联,为预防和治疗脑卒中后衰弱提供思路。方法采用横断面研究,基于2011—2018年美国国家健康营养调查(the US National Health and Nutrition Examination Survey,NHANES)老年脑卒中人群数据,依据衰弱指数将研究对象分为对照组和衰弱组,计算DII并收集相关协变量数据。多因素logistic回归被用于分析DII和脑卒中后衰弱的关联性,构建限制性立方样条(restricted cubic spline,RCS)模型以明确DII和脑卒中后衰弱的剂量-反应关系。结果共纳入1340例老年脑卒中患者,检出衰弱患者719例,衰弱发生率为53.66%。总体DII中位数为1.32,衰弱组DII高于对照组,组间差异有统计学意义(Z=-5.719,P<0.001)。logistic回归分析结果表明,在调整所有协变量后,DII升高仍与较高的衰弱发生率显著相关(OR=1.463~1.886,P<0.05),趋势性检验差异有统计学意义(P<0.05)。RCS模型显示DII与老年人群脑卒中后衰弱呈正向线性相关(非线性P=0.376)。结论老年人群脑卒中后衰弱发生率较高,DII与衰弱风险增高相关,制定合理的膳食计划有利于预防衰弱的发生。
基金Funded by the National Key R&D Program of China (No. 2018YFC0406702)the National Natural Science Foundation of China (No. 51739008)+2 种基金Special Fund for Basic Research Business Expenses of Central Public Welfare Research Institute (No. Y419004)Yunnan Provincial Department of Transportation Industry Science and Technology ProjectJiangsu Natural Science Fund (No. BK20181516)
文摘Triisopropanolamine (TIPA) was used as an early strength component to study its effects on mortar strength, cement paste setting time and early hydration characteristic of cement. And the early strength mechanism of TIPA at low temperature of 5 ℃ was also discussed. The results showed that, at 5 ℃, the incorporation of TIPA promoted the condensation of cement paste, shortened the initial and final setting time, and accelerated the strength development of specimens at all ages, among which the strength after 3 d increased significantly. The 1, 3, 7, and 28 d compressive strength ratios of the mortars mixed with 1% TIPA could reach 196%, 179%, 160% and 110% respectively, and the mortar strength after 3 d exceeded that of the contrast sample cured at 20 ℃. Under low temperature condition, TIPA could promote the hydration reaction of cement, shorten the induction period and advance the acceleration period. Furthermore, the maximum heat release rate and cumulative heat release quantity would be all increased, and the cumulative heat release of the cement mixed with TIPA hydrated for 12 h and 7 d increased 73% and 38% respectively. TIPA could shorten the nucleation and crystal growth (NG) stage and increase its hydration degree significantly, so it promoted cement hydration reaction. Additionally, the hydration reaction rates in phase boundary reaction (I) phase and diffusion reaction (D) phase were increased, and the duration of I process was prolonged, thereby the development of specimen strength would be accelerated. TIPA did not obviously change the types of hydration products, but increased the content of Ca(OH)2 in the samples and the degree of cement hydration. After hydration to 7 d, large amounts of hydration products, whose surface was smooth, were formed and bonded into sheets, and the structural density of samples improved significantly.
