Efficiency and accuracy are two major concerns in numerical solutions of the Poisson-Boltzmann equation for applications in chemistry and biophysics.Recent developments in boundary element methods,interface methods,ad...Efficiency and accuracy are two major concerns in numerical solutions of the Poisson-Boltzmann equation for applications in chemistry and biophysics.Recent developments in boundary element methods,interface methods,adaptive methods,finite element methods,and other approaches for the Poisson-Boltzmann equation as well as related mesh generation techniques are reviewed.We also discussed the challenging problems and possible future work,in particular,for the aim of biophysical applications.展开更多
基金the NIH,NSF,the Howard Hughes Medical Institute,National Biomedical Computing Resource,the NSF Center for Theoretical Biological Physics,SDSC,the W.M.Keck Foundation,and Accelrys,Inc.Michael Holst was supported in part by NSF Awards 0411723,0511766,and 0225630,and DOE Awards DEFG02-05ER25707 and DE-FG02-04ER25620.
文摘Efficiency and accuracy are two major concerns in numerical solutions of the Poisson-Boltzmann equation for applications in chemistry and biophysics.Recent developments in boundary element methods,interface methods,adaptive methods,finite element methods,and other approaches for the Poisson-Boltzmann equation as well as related mesh generation techniques are reviewed.We also discussed the challenging problems and possible future work,in particular,for the aim of biophysical applications.
