<span style="font-family:Verdana;">The new coronavirus called SARS-CoV-2 is a new type of virus named as COVID-19. Although, </span><span style="font-family:Verdana;">it has </...<span style="font-family:Verdana;">The new coronavirus called SARS-CoV-2 is a new type of virus named as COVID-19. Although, </span><span style="font-family:Verdana;">it has </span><span style="font-family:Verdana;">few similarities with pandemic flu viruses</span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;"> the respiratory system and immune system are damaged through the viruses infected the population wh</span><span style="font-family:Verdana;">o</span><span style="font-family:Verdana;"> has weakened immunity. SARS-CoV-2 spread</span><span style="font-family:Verdana;">s</span><span style="font-family:Verdana;"> when people don’t have the sign and symptoms. This virus COVID-19 appears to spread more easily than the flu, and asymptomatic transmission may account for a greater proportion of COVID-19’s spreader over the World. In inundation of the current understanding</span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;"> the roles of insect vectors are helping in the transmission of viral pathogens as well and the possible roles of some newly joined insects in the mechanical transmission of COVID-19.</span><span style="font-family:Verdana;"> We also specifically provide the prevention and control methods related to contamination, disease burden, risk pattern in the family, near and dear to maintain the precision of social distancing and development of the immune system to fight against SARS-CoV-2.展开更多
An otherwise healthy, full-term neonate presented at day 15 of life to the pediatric emergency with generalized papulo-pustular rash for 2 d. This was finally diagnosed as bullous impetigo caused by Staphylococcus aur...An otherwise healthy, full-term neonate presented at day 15 of life to the pediatric emergency with generalized papulo-pustular rash for 2 d. This was finally diagnosed as bullous impetigo caused by Staphylococcus aureus(S. aureus). The skin lesions decreased significantly after starting antibiotic therapy and drainage of blister fluid. There was no recurrence of the lesions on followup. This case of generalized pustular eruption due to S. aureus in a neonate is reported, as it poses a diagnostic dilemma and can have serious consequences if left untreated.展开更多
Magnesium(Mg)is renowned for its unique combination of low weight,high strength-to-weight ratio,biocompatibility,and natural abundance,positioning it as an ideal candidate for biodegradable implants in biomedicine.Des...Magnesium(Mg)is renowned for its unique combination of low weight,high strength-to-weight ratio,biocompatibility,and natural abundance,positioning it as an ideal candidate for biodegradable implants in biomedicine.Despite these advantageous properties,challenges such as poor formability and susceptibility to corrosion have restricted its broader application.This review critically addresses these limitations by delving into Mg’s biodegradation mechanisms and the various degradation modes activated by different physiological environments.Emphasis is placed on understanding these processes to optimize Mg’s utility as a biomaterial.Additionally,the transformative potential of integrating rare-earth(RE)elements into Mg alloys is explored.These elements significantly refine the microstructure,enhance mechanical properties,and improve corrosion resistance,effectively mitigating some of Mg’s inherent limitations.Rare earth elements(REEs)significantly improve the mechanical properties of magnesium alloys.Cerium and lanthanum form protective oxide layers,reducing corrosion.Neodymium prevents hydrogen embrittlement,while yttrium refines grain size.The combination of REEs offers a diverse range of properties,including enhanced strength,creep resistance,high-temperature performance,corrosion resistance,ductility,and toughness.This versatility allows for tailored alloy selection for specific applications.The review also assesses the effects of various RE elements on biodegradability,cytotoxicity,and biological interaction,which are crucial for medical applications.Furthermore,the innovative realm of additive manufacturing(AM)is investigated to develop efficient Mg-RE-based biomedical implants,enabling the precise customization of implants to meet individual patient needs.Through a comprehensive evaluation of the latest research,this study projects the promising future of Mg-RE alloys as groundbreaking biomaterials poised to redefine medical implant technology with their superior mechanical and biological properties.展开更多
Objective： To report a case ser/es of six neglected cervical spine dislocations without neurological deficit, which were managed operatively. Methods： The study was conducted fromAugust 2010 to December 2011 and ca...Objective： To report a case ser/es of six neglected cervical spine dislocations without neurological deficit, which were managed operatively. Methods： The study was conducted fromAugust 2010 to December 2011 and cases were selected from the out- patient department of Postgraduate Institute of Medical Education and Research, India. The patients were in the age group of 30 to 50 years. All patients were operated via both anterior and posterior approaches. Results： During the immediate postoperative period, five （83.33%） patients had normal neurological status. One （16.67%） patient who had C5-C6 subluxation developed neu- rological deficit with sensory loss below C6 level and motor power of 2/5 in the lower limb and 3/5 in the upper limb below C6 level. Conclusion： There is no role of skull traction in ne- glected distractive flexion injuries to cervical spine delayed for more than 3 weeks. Posterior followed by anterior ap- proach saves much time. If both approaches are to be done in the same sitting, there is no need for instrumentation posteriorly. But if staged procedure is planed, posterior sta- bilization is recommended, as there is a risk of deterioration in neurological status.展开更多
The physis of a long bone may get ＇sandwiched＇ and crushed between the metaphysis and the epiphysis if it is traumatically loaded along its long axis. Such a physeal injury may lead to complications like angular def...The physis of a long bone may get ＇sandwiched＇ and crushed between the metaphysis and the epiphysis if it is traumatically loaded along its long axis. Such a physeal injury may lead to complications like angular deformities and growth restrictions and hence, management of such injuries requires adequate planning and attentive execution. Two patients with distal femoral physeal crush injury were treated using a ring fixator such that one ring had the wires passing through the epiphysis and the other through the femoral shaft. On table image intensifier controlled distraction of the crushed physis was done to bring the height of the physis similar to that of the opposite limb. Patients were followed up for more than two years clinically and radio- logically. There was no clinical or radiological angular deformity of the operated limbs. MRI scans showed intact physes with no physeal bar formation in either of the two patients. The distraction obtained by the ring fixator appears to have provided ample ＇breathing space＇ to the compressed physis and that the growth potential may have been re-gained by the procedure. However, two years is a relatively short duration of follow-up and further follow-up of longer duration and in greater number of patients is needed to gauge the actual effectiveness of the technque used bv us.展开更多
Radial head and coronoid fractures without posterior dislocation of the elbow have not been recorded in the literature. There is no literature documenting the combined fractures of the radial head, capitellum and coro...Radial head and coronoid fractures without posterior dislocation of the elbow have not been recorded in the literature. There is no literature documenting the combined fractures of the radial head, capitellum and coronoid process together in the same elbow. This is a case report highlighting this combination of fractures in a 30 year old patient treated with open reduction and internal fixation of all three fractures. The patient was followed up for 28 months and had a good range of motion of the elbow without any instabiliW. Thus such a triad with no ligamentous injuries could depict a bony variant of terrible triad and a mechanism for such an injury has also been explained.展开更多
文摘<span style="font-family:Verdana;">The new coronavirus called SARS-CoV-2 is a new type of virus named as COVID-19. Although, </span><span style="font-family:Verdana;">it has </span><span style="font-family:Verdana;">few similarities with pandemic flu viruses</span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;"> the respiratory system and immune system are damaged through the viruses infected the population wh</span><span style="font-family:Verdana;">o</span><span style="font-family:Verdana;"> has weakened immunity. SARS-CoV-2 spread</span><span style="font-family:Verdana;">s</span><span style="font-family:Verdana;"> when people don’t have the sign and symptoms. This virus COVID-19 appears to spread more easily than the flu, and asymptomatic transmission may account for a greater proportion of COVID-19’s spreader over the World. In inundation of the current understanding</span><span style="font-family:Verdana;">,</span><span style="font-family:Verdana;"> the roles of insect vectors are helping in the transmission of viral pathogens as well and the possible roles of some newly joined insects in the mechanical transmission of COVID-19.</span><span style="font-family:Verdana;"> We also specifically provide the prevention and control methods related to contamination, disease burden, risk pattern in the family, near and dear to maintain the precision of social distancing and development of the immune system to fight against SARS-CoV-2.
文摘An otherwise healthy, full-term neonate presented at day 15 of life to the pediatric emergency with generalized papulo-pustular rash for 2 d. This was finally diagnosed as bullous impetigo caused by Staphylococcus aureus(S. aureus). The skin lesions decreased significantly after starting antibiotic therapy and drainage of blister fluid. There was no recurrence of the lesions on followup. This case of generalized pustular eruption due to S. aureus in a neonate is reported, as it poses a diagnostic dilemma and can have serious consequences if left untreated.
文摘Magnesium(Mg)is renowned for its unique combination of low weight,high strength-to-weight ratio,biocompatibility,and natural abundance,positioning it as an ideal candidate for biodegradable implants in biomedicine.Despite these advantageous properties,challenges such as poor formability and susceptibility to corrosion have restricted its broader application.This review critically addresses these limitations by delving into Mg’s biodegradation mechanisms and the various degradation modes activated by different physiological environments.Emphasis is placed on understanding these processes to optimize Mg’s utility as a biomaterial.Additionally,the transformative potential of integrating rare-earth(RE)elements into Mg alloys is explored.These elements significantly refine the microstructure,enhance mechanical properties,and improve corrosion resistance,effectively mitigating some of Mg’s inherent limitations.Rare earth elements(REEs)significantly improve the mechanical properties of magnesium alloys.Cerium and lanthanum form protective oxide layers,reducing corrosion.Neodymium prevents hydrogen embrittlement,while yttrium refines grain size.The combination of REEs offers a diverse range of properties,including enhanced strength,creep resistance,high-temperature performance,corrosion resistance,ductility,and toughness.This versatility allows for tailored alloy selection for specific applications.The review also assesses the effects of various RE elements on biodegradability,cytotoxicity,and biological interaction,which are crucial for medical applications.Furthermore,the innovative realm of additive manufacturing(AM)is investigated to develop efficient Mg-RE-based biomedical implants,enabling the precise customization of implants to meet individual patient needs.Through a comprehensive evaluation of the latest research,this study projects the promising future of Mg-RE alloys as groundbreaking biomaterials poised to redefine medical implant technology with their superior mechanical and biological properties.
文摘Objective： To report a case ser/es of six neglected cervical spine dislocations without neurological deficit, which were managed operatively. Methods： The study was conducted fromAugust 2010 to December 2011 and cases were selected from the out- patient department of Postgraduate Institute of Medical Education and Research, India. The patients were in the age group of 30 to 50 years. All patients were operated via both anterior and posterior approaches. Results： During the immediate postoperative period, five （83.33%） patients had normal neurological status. One （16.67%） patient who had C5-C6 subluxation developed neu- rological deficit with sensory loss below C6 level and motor power of 2/5 in the lower limb and 3/5 in the upper limb below C6 level. Conclusion： There is no role of skull traction in ne- glected distractive flexion injuries to cervical spine delayed for more than 3 weeks. Posterior followed by anterior ap- proach saves much time. If both approaches are to be done in the same sitting, there is no need for instrumentation posteriorly. But if staged procedure is planed, posterior sta- bilization is recommended, as there is a risk of deterioration in neurological status.
文摘The physis of a long bone may get ＇sandwiched＇ and crushed between the metaphysis and the epiphysis if it is traumatically loaded along its long axis. Such a physeal injury may lead to complications like angular deformities and growth restrictions and hence, management of such injuries requires adequate planning and attentive execution. Two patients with distal femoral physeal crush injury were treated using a ring fixator such that one ring had the wires passing through the epiphysis and the other through the femoral shaft. On table image intensifier controlled distraction of the crushed physis was done to bring the height of the physis similar to that of the opposite limb. Patients were followed up for more than two years clinically and radio- logically. There was no clinical or radiological angular deformity of the operated limbs. MRI scans showed intact physes with no physeal bar formation in either of the two patients. The distraction obtained by the ring fixator appears to have provided ample ＇breathing space＇ to the compressed physis and that the growth potential may have been re-gained by the procedure. However, two years is a relatively short duration of follow-up and further follow-up of longer duration and in greater number of patients is needed to gauge the actual effectiveness of the technque used bv us.
文摘Radial head and coronoid fractures without posterior dislocation of the elbow have not been recorded in the literature. There is no literature documenting the combined fractures of the radial head, capitellum and coronoid process together in the same elbow. This is a case report highlighting this combination of fractures in a 30 year old patient treated with open reduction and internal fixation of all three fractures. The patient was followed up for 28 months and had a good range of motion of the elbow without any instabiliW. Thus such a triad with no ligamentous injuries could depict a bony variant of terrible triad and a mechanism for such an injury has also been explained.
