The mini-review explores the potential use of alginates produced biotechnologically by bacteria for the development of various implantable biomaterials intended for bone and cartilage tissue regeneration in orthopedic...The mini-review explores the potential use of alginates produced biotechnologically by bacteria for the development of various implantable biomaterials intended for bone and cartilage tissue regeneration in orthopedics:the recent studies on the use of algal alginate-based biomaterials in the form of hydrogels,scaffolds,and microparticles for medical applications are considered as a potential opportunity to use bacterial alginate for these applications,taking into account the advantages of biotechnological production of a polymer with desired properties.The methods of producing different alginate-based biomaterials,the manufacturing of implantable medical devices using them,and the surgical techniques for bone and cartilage tissue regeneration using these materials for orthopedic purposes are discussed.展开更多
基金Supported by Russian Science Foundation,No.23-74-10027.
文摘The mini-review explores the potential use of alginates produced biotechnologically by bacteria for the development of various implantable biomaterials intended for bone and cartilage tissue regeneration in orthopedics:the recent studies on the use of algal alginate-based biomaterials in the form of hydrogels,scaffolds,and microparticles for medical applications are considered as a potential opportunity to use bacterial alginate for these applications,taking into account the advantages of biotechnological production of a polymer with desired properties.The methods of producing different alginate-based biomaterials,the manufacturing of implantable medical devices using them,and the surgical techniques for bone and cartilage tissue regeneration using these materials for orthopedic purposes are discussed.