Single-edged notched tension （SENT） specimen is used to study the fatigue crack growth rate （FCGR） behavior of AISI 50100 steel using MTS 810. Calibration tests are run to get plots of crack mouth opening displace...Single-edged notched tension （SENT） specimen is used to study the fatigue crack growth rate （FCGR） behavior of AISI 50100 steel using MTS 810. Calibration tests are run to get plots of crack mouth opening displacement （CMOD） vs. load and CMOD vs. crack length-to-width ratio with the known crack lengths. Numerical simulation is also done to try to establish a relation between crack length and CMOD. FCGR of welded and un-welded specimens are plotted against stress intensity factor range to show the effect of welding on fatigue crack growth rate of AISI 50100 steel. The experimentally obtained CMOD values are compared with values obtained by numerical simulation using ABAQUS/StandardTM software package. Results show that numerical values are in good agreement with experimental data for small crack lengths and lower values of applied load,展开更多
Hepatitis B infection(HBV)is one of the most common causes of hepatocellular carcinoma(HCC)worldwide.The age of occurrence,prognosis and incidence vary dramatically depending on the region of the world.This geographic...Hepatitis B infection(HBV)is one of the most common causes of hepatocellular carcinoma(HCC)worldwide.The age of occurrence,prognosis and incidence vary dramatically depending on the region of the world.This geographic variation is largely dependent on the contrasting incidence of HBV,age of transmission of the virus,the timing of integration into the human genome,and different HBV genotypes,as well as environmental factors.It results in a wide difference in viral interaction with the immune system,genomic modulation and the consequent development of HCC in an individual.In this review,we describe many factors implicated in HCC development,provide insight regarding at-risk populations and explain societal recommendations for HCC surveillance in persons living with HBV in different continents of the world.展开更多
基金supported by University of Engineering and Technology, Taxila
文摘Single-edged notched tension （SENT） specimen is used to study the fatigue crack growth rate （FCGR） behavior of AISI 50100 steel using MTS 810. Calibration tests are run to get plots of crack mouth opening displacement （CMOD） vs. load and CMOD vs. crack length-to-width ratio with the known crack lengths. Numerical simulation is also done to try to establish a relation between crack length and CMOD. FCGR of welded and un-welded specimens are plotted against stress intensity factor range to show the effect of welding on fatigue crack growth rate of AISI 50100 steel. The experimentally obtained CMOD values are compared with values obtained by numerical simulation using ABAQUS/StandardTM software package. Results show that numerical values are in good agreement with experimental data for small crack lengths and lower values of applied load,
基金supported by Robert Wood Johnson Foundation,Harold Amos Medical Faculty Development Program,NIH-NCI R21 CA215883-01A1 and University of Minnesota AIRP grant,all to JDD.
文摘Hepatitis B infection(HBV)is one of the most common causes of hepatocellular carcinoma(HCC)worldwide.The age of occurrence,prognosis and incidence vary dramatically depending on the region of the world.This geographic variation is largely dependent on the contrasting incidence of HBV,age of transmission of the virus,the timing of integration into the human genome,and different HBV genotypes,as well as environmental factors.It results in a wide difference in viral interaction with the immune system,genomic modulation and the consequent development of HCC in an individual.In this review,we describe many factors implicated in HCC development,provide insight regarding at-risk populations and explain societal recommendations for HCC surveillance in persons living with HBV in different continents of the world.
