BACKGROUND Normothermic machine perfusion(NMP)utilizing OCS Liver is becoming increasingly common in adult liver transplantation(LT),but not in pediatric transplantation.OCS Liver has been shown to decrease post-reper...BACKGROUND Normothermic machine perfusion(NMP)utilizing OCS Liver is becoming increasingly common in adult liver transplantation(LT),but not in pediatric transplantation.OCS Liver has been shown to decrease post-reperfusion syndrome and early allograft dysfunction after transplantation.We describe the first case series of three pediatric patients who received a liver transplant using livers CASE SUMMARY Three pediatric patients,all with different etiologies of liver disease,were successfully transplanted with livers preserved with NMP.All patients are currently doing well with follow-ups of 7 to 16 months post-transplant.CONCLUSION The use of OCS Liver in pediatric LT is feasible and can be performed even in the sickest recipients with excellent outcomes.Utilization of OCS Liver can optimize donor and recipient factors to allow for optimal outcomes.展开更多
文摘BACKGROUND Normothermic machine perfusion(NMP)utilizing OCS Liver is becoming increasingly common in adult liver transplantation(LT),but not in pediatric transplantation.OCS Liver has been shown to decrease post-reperfusion syndrome and early allograft dysfunction after transplantation.We describe the first case series of three pediatric patients who received a liver transplant using livers CASE SUMMARY Three pediatric patients,all with different etiologies of liver disease,were successfully transplanted with livers preserved with NMP.All patients are currently doing well with follow-ups of 7 to 16 months post-transplant.CONCLUSION The use of OCS Liver in pediatric LT is feasible and can be performed even in the sickest recipients with excellent outcomes.Utilization of OCS Liver can optimize donor and recipient factors to allow for optimal outcomes.
