The biorefinery approach ensures a sustainable source of valuable fatty acids and opens up new avenues for their application in healthcare industries.Recent studies highlight the health benefits of omega-PUFAs,spurrin...The biorefinery approach ensures a sustainable source of valuable fatty acids and opens up new avenues for their application in healthcare industries.Recent studies highlight the health benefits of omega-PUFAs,spurring the search for cost-effective production methods.Microbial platforms are promising for high-yield PUFA production,withω-3 dominating the market.ω-3 PUFAs offer antioxidant and anti-inflammatory effects,reducing illness risk,while all PUFAs contribute to cardiovascular health,diabetes prevention,cancer risk reduction,and more.ω-6 PUFAs,particularly linoleic acid(LA)and arachidonic acid(ARA),play vital roles in various aspects of health,making them high-demand bioavailable compounds.Additionally,docosahexaenoic acid(DHA)and eicosapentaenoic acid(EPA)exhibit potential benefits in brain development and COVID-19 prevention.This comprehensive review provides insights into the state-of-the-art microbial biorefinery strategies forω-3 andω-6 PUFA production and their wide-ranging health-related benefits.展开更多
Correction:Systems Microbiology and Biomanufacturing https://doi.org/10.1007/s43393-023-00207-x In this article the affiliation details for Author Tirath Raj were incorrectly given as Center for Advanced Bioenergy and...Correction:Systems Microbiology and Biomanufacturing https://doi.org/10.1007/s43393-023-00207-x In this article the affiliation details for Author Tirath Raj were incorrectly given as Center for Advanced Bioenergy and Bioproducts Innovation(CABBI),University of Illinois Urbana Champaign,AESB,1304 West Pennsylvania Avenue I,Urbana,IL 61801,USA but should have been Department of Agricultural and Biological Engineering,University of Illinois Urbana-Champaign,1304 West Pennsylvania Avenue,Urbana,IL,61801,USA.展开更多
基金acknowledges NSTC,Taiwan,for funding support(Ref.No.NSTC 112-2222-E-992-006-MY2)the National Kaohsiung University of Science and Technology 112 Annual Marine Characteristics Sustainable Development Research Program(Program code 112A14).
文摘The biorefinery approach ensures a sustainable source of valuable fatty acids and opens up new avenues for their application in healthcare industries.Recent studies highlight the health benefits of omega-PUFAs,spurring the search for cost-effective production methods.Microbial platforms are promising for high-yield PUFA production,withω-3 dominating the market.ω-3 PUFAs offer antioxidant and anti-inflammatory effects,reducing illness risk,while all PUFAs contribute to cardiovascular health,diabetes prevention,cancer risk reduction,and more.ω-6 PUFAs,particularly linoleic acid(LA)and arachidonic acid(ARA),play vital roles in various aspects of health,making them high-demand bioavailable compounds.Additionally,docosahexaenoic acid(DHA)and eicosapentaenoic acid(EPA)exhibit potential benefits in brain development and COVID-19 prevention.This comprehensive review provides insights into the state-of-the-art microbial biorefinery strategies forω-3 andω-6 PUFA production and their wide-ranging health-related benefits.
文摘Correction:Systems Microbiology and Biomanufacturing https://doi.org/10.1007/s43393-023-00207-x In this article the affiliation details for Author Tirath Raj were incorrectly given as Center for Advanced Bioenergy and Bioproducts Innovation(CABBI),University of Illinois Urbana Champaign,AESB,1304 West Pennsylvania Avenue I,Urbana,IL 61801,USA but should have been Department of Agricultural and Biological Engineering,University of Illinois Urbana-Champaign,1304 West Pennsylvania Avenue,Urbana,IL,61801,USA.