In a recent study published in Nature,Doglioni et al.now reveal an unexpected role for the amino acid aspartate as a signalling molecule that induces alternative translation that ultimately promotes lung metastasis th...In a recent study published in Nature,Doglioni et al.now reveal an unexpected role for the amino acid aspartate as a signalling molecule that induces alternative translation that ultimately promotes lung metastasis through enhanced collagen secretion.^(1) Metastasis remains the leading cause of cancer-related deaths and many aspects of the metastatic process remain poorly understood.展开更多
基金the German Research Foundation(FOR-2314 and SPP-2306).
文摘In a recent study published in Nature,Doglioni et al.now reveal an unexpected role for the amino acid aspartate as a signalling molecule that induces alternative translation that ultimately promotes lung metastasis through enhanced collagen secretion.^(1) Metastasis remains the leading cause of cancer-related deaths and many aspects of the metastatic process remain poorly understood.
