·AIM:To identify various risk factors that may play a significant role in the development of congenital nasolacrimal duct obstruction(CNLDO).·METHODS:This observational case-control study included a case gro...·AIM:To identify various risk factors that may play a significant role in the development of congenital nasolacrimal duct obstruction(CNLDO).·METHODS:This observational case-control study included a case group of 122 children less than two years of age with CNLDO who underwent probing and irrigation treatment at the ophthalmology department of Imam Khomeini Hospital in Ahvaz,Iran,from June 2022 to June2024.A control group of 122 age-matched children without CNLDO was also included for comparison.Data was collected from the children's medical records.·RESULTS:The study found a significant correlation between the occurrence of CNLDO and several maternal factors,such as preeclampsia,the use of levothyroxine,hypothyroidism,having more than three pregnancies(gravidity>3),natural pregnancy,and gestational diabetes mellitus.Additionally,in children,factors,such as oxygen therapy,anemia,reflux,jaundice,and a family history of CNLDO in first-degree relatives were associated with CNLDO,and maternal preeclampsia and hypothyroidism were found to significantly increase the risk of developing CNLDO in children.·CONCLUSION:Given that CNLDO affects both premature and full-term children,the present findings may potentially facilitate the early identification of children and infants at risk of nasolacrimal duct obstruction,thereby preventing the onset of chronic dacryocystitis.展开更多
Dear Editor,We present the reported case of rapid onset bull’s eye maculopathy.Chloroquine(CQ)and its safer,more widely used analogue,hydroxychloroquine(HCQ),were originally developed as antimalarial medications.Howe...Dear Editor,We present the reported case of rapid onset bull’s eye maculopathy.Chloroquine(CQ)and its safer,more widely used analogue,hydroxychloroquine(HCQ),were originally developed as antimalarial medications.However,they have since become essential in the treatment of various autoimmune disorders due to their anti-inflammatory and immunomodulatory properties.HCQ is also being investigated for potential applications in diabetes mellitus,coronavirus disease 2019,heart disease,and as an adjunct in cancer therapy^([1-2]).展开更多
The aim of this study was to establish diabetic retinopathy correlation with several risk factors. A prospective study including 256 type II diabetic patients who referred to diabetes’s clinic was designed. All patie...The aim of this study was to establish diabetic retinopathy correlation with several risk factors. A prospective study including 256 type II diabetic patients who referred to diabetes’s clinic was designed. All patients underwent physical & retina examination and then completed questionnaire including duration of DM, cardiovascular disease, stroke, chronic kidney disease, smoking, and kind of treatment, blood pressure, BMI, abdominal & hip circumference. Results of HbA1C, total cholesterol, HDL & LDL cholesterol, TG, FBS, creatinine, 24-h urine microalbumin were recorded. Data were analyzed by SPSS version 17 with K2, independent samples T, and logistic regression. Of 256 types II diabetic patients 81 & 175 were men and women respectively. Mean age of subject was 54 ± 10.27. Prevalence of diabetic retinopathy was 22.3% & macula edema 0.5% & PDR 6% & NPDR 14%;diabetic retinopathy was associated with duration of DM & BMI (P = 0, P = 0.43 respectively). Mean of FBS 191 ± 83 vs. 165.7 ± 74.5 (P = 0.03), HbA1c 9.1 ± 2 vs. 8.5 ± 1.9 (P = 0.02), 24-h urine microalbumin 181.2 ± 404.7 vs. 60.2 ± 236 (P = 0.03), Systolic blood pressure 124.3 ± 21.3 vs. 118.5 ± 17.8 (p = 0.04) differed between diabetic patients with or without diabetic retinopathy. There were no significant difference between subject with & without diabetic retinopathy in total cholesterol LDL, HDL, TG, Cr, Diastolic BP, types of treatment, cardiovascular disease, chronic kidney disease, stroke & smoking. This study showed prevalence of diabetic retinopathy was high and it associated with duration of DM, BMI, FBS, HbA1C, 24-h urine albumin, and systolic blood pressure.展开更多
Objective:To examine the epidemiological features of cutaneous leishmaniasis in Genaveh County,Southern Iran.Methods:This descriptive study was conducted during 2004-2008.A questionnaire was completed for each case re...Objective:To examine the epidemiological features of cutaneous leishmaniasis in Genaveh County,Southern Iran.Methods:This descriptive study was conducted during 2004-2008.A questionnaire was completed for each case regarding age,gender,place of residence,the number and location of cutaneous leishmaniasis lesions etc.Suspected active lesions were scraped with a sterile blade and the samples smeared onto glass slides,fixed with methanol,stained with Giemsa and examined under a light microscope for the presence of amastigotes.Results:Totally,135 cases of cutaneous leishmaniasis came to the health centers.The highest number of patients catching cutaneous leishmaniasis was found in 2006(n=54).Most cases(56.3%)occurred during winter.The most highly infected age group was 1 to 10 years.The hands were the most affected parts of the body.About 54%of the patients had one lesion.The most cases(53.3%)occurred in rural areas.Concluions:It is important for the health authorities to take powerful actions to control cutaneous leishmaniasis.Meanwhile,It is significant to prepare quick treatment of cases.展开更多
文摘·AIM:To identify various risk factors that may play a significant role in the development of congenital nasolacrimal duct obstruction(CNLDO).·METHODS:This observational case-control study included a case group of 122 children less than two years of age with CNLDO who underwent probing and irrigation treatment at the ophthalmology department of Imam Khomeini Hospital in Ahvaz,Iran,from June 2022 to June2024.A control group of 122 age-matched children without CNLDO was also included for comparison.Data was collected from the children's medical records.·RESULTS:The study found a significant correlation between the occurrence of CNLDO and several maternal factors,such as preeclampsia,the use of levothyroxine,hypothyroidism,having more than three pregnancies(gravidity>3),natural pregnancy,and gestational diabetes mellitus.Additionally,in children,factors,such as oxygen therapy,anemia,reflux,jaundice,and a family history of CNLDO in first-degree relatives were associated with CNLDO,and maternal preeclampsia and hypothyroidism were found to significantly increase the risk of developing CNLDO in children.·CONCLUSION:Given that CNLDO affects both premature and full-term children,the present findings may potentially facilitate the early identification of children and infants at risk of nasolacrimal duct obstruction,thereby preventing the onset of chronic dacryocystitis.
文摘Dear Editor,We present the reported case of rapid onset bull’s eye maculopathy.Chloroquine(CQ)and its safer,more widely used analogue,hydroxychloroquine(HCQ),were originally developed as antimalarial medications.However,they have since become essential in the treatment of various autoimmune disorders due to their anti-inflammatory and immunomodulatory properties.HCQ is also being investigated for potential applications in diabetes mellitus,coronavirus disease 2019,heart disease,and as an adjunct in cancer therapy^([1-2]).
文摘The aim of this study was to establish diabetic retinopathy correlation with several risk factors. A prospective study including 256 type II diabetic patients who referred to diabetes’s clinic was designed. All patients underwent physical & retina examination and then completed questionnaire including duration of DM, cardiovascular disease, stroke, chronic kidney disease, smoking, and kind of treatment, blood pressure, BMI, abdominal & hip circumference. Results of HbA1C, total cholesterol, HDL & LDL cholesterol, TG, FBS, creatinine, 24-h urine microalbumin were recorded. Data were analyzed by SPSS version 17 with K2, independent samples T, and logistic regression. Of 256 types II diabetic patients 81 & 175 were men and women respectively. Mean age of subject was 54 ± 10.27. Prevalence of diabetic retinopathy was 22.3% & macula edema 0.5% & PDR 6% & NPDR 14%;diabetic retinopathy was associated with duration of DM & BMI (P = 0, P = 0.43 respectively). Mean of FBS 191 ± 83 vs. 165.7 ± 74.5 (P = 0.03), HbA1c 9.1 ± 2 vs. 8.5 ± 1.9 (P = 0.02), 24-h urine microalbumin 181.2 ± 404.7 vs. 60.2 ± 236 (P = 0.03), Systolic blood pressure 124.3 ± 21.3 vs. 118.5 ± 17.8 (p = 0.04) differed between diabetic patients with or without diabetic retinopathy. There were no significant difference between subject with & without diabetic retinopathy in total cholesterol LDL, HDL, TG, Cr, Diastolic BP, types of treatment, cardiovascular disease, chronic kidney disease, stroke & smoking. This study showed prevalence of diabetic retinopathy was high and it associated with duration of DM, BMI, FBS, HbA1C, 24-h urine albumin, and systolic blood pressure.
基金Supported by Chancellor for Research Affairs of Ahvaz Jundishapur University of Medical Sciences(project number 88S.95).
文摘Objective:To examine the epidemiological features of cutaneous leishmaniasis in Genaveh County,Southern Iran.Methods:This descriptive study was conducted during 2004-2008.A questionnaire was completed for each case regarding age,gender,place of residence,the number and location of cutaneous leishmaniasis lesions etc.Suspected active lesions were scraped with a sterile blade and the samples smeared onto glass slides,fixed with methanol,stained with Giemsa and examined under a light microscope for the presence of amastigotes.Results:Totally,135 cases of cutaneous leishmaniasis came to the health centers.The highest number of patients catching cutaneous leishmaniasis was found in 2006(n=54).Most cases(56.3%)occurred during winter.The most highly infected age group was 1 to 10 years.The hands were the most affected parts of the body.About 54%of the patients had one lesion.The most cases(53.3%)occurred in rural areas.Concluions:It is important for the health authorities to take powerful actions to control cutaneous leishmaniasis.Meanwhile,It is significant to prepare quick treatment of cases.
