<p class="Abstract"style="margin:0 cm;line-height:32px;font-size:12 pt;font-family:"Times New Roman",serif;color:rgb(0,0,0);"><span lang="EN-US">The carious process ...<p class="Abstract"style="margin:0 cm;line-height:32px;font-size:12 pt;font-family:"Times New Roman",serif;color:rgb(0,0,0);"><span lang="EN-US">The carious process leads to inflammation of pulp tissue.Current care options include root canal treatment or apexification.These procedures,however,result in the loss of tooth vitality,sensitivity,and healing.Pulp capping and dental pulp regeneration are continually evolving techniques to regenerate pulp tissue,avoiding necrosis and loss of vitality.Many studies have successfully employed stem/progenitor cell populations,revascularization approaches,scaffolds or material-based strategies for pulp regeneration.Here we outline advantages and disadvantages of different methods and techniques which are currently being used in the field of regenerative endodontics.We also summarize recent findings on efficacious peptide-based materials which target the dental niche.<o:p></o:p>.展开更多
基金supported by grants NIH R15 EY02950401A1S1 for AAJNIH R15 EY029504+2 种基金NSF IIP 1903617the NJIT Undergraduate Research and Innovation(URI)Program for VAKNIH grant R01DE025885 to E.S.
文摘<p class="Abstract"style="margin:0 cm;line-height:32px;font-size:12 pt;font-family:"Times New Roman",serif;color:rgb(0,0,0);"><span lang="EN-US">The carious process leads to inflammation of pulp tissue.Current care options include root canal treatment or apexification.These procedures,however,result in the loss of tooth vitality,sensitivity,and healing.Pulp capping and dental pulp regeneration are continually evolving techniques to regenerate pulp tissue,avoiding necrosis and loss of vitality.Many studies have successfully employed stem/progenitor cell populations,revascularization approaches,scaffolds or material-based strategies for pulp regeneration.Here we outline advantages and disadvantages of different methods and techniques which are currently being used in the field of regenerative endodontics.We also summarize recent findings on efficacious peptide-based materials which target the dental niche.<o:p></o:p>.
