Epithelioid sarcoma(EpS)is an aggressive soft tissue sarcoma characterized by switch/sucrose non-fermentable(SWI/SNF)-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1(SMARCB1)loss[...Epithelioid sarcoma(EpS)is an aggressive soft tissue sarcoma characterized by switch/sucrose non-fermentable(SWI/SNF)-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1(SMARCB1)loss[1].Conventionally,EpS is histologically classified as either distal or proximal subtype,each exhibiting distinct clinical behaviors;these sometimes co-exist as“hybrid”EpS[2,3].展开更多
文摘Epithelioid sarcoma(EpS)is an aggressive soft tissue sarcoma characterized by switch/sucrose non-fermentable(SWI/SNF)-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1(SMARCB1)loss[1].Conventionally,EpS is histologically classified as either distal or proximal subtype,each exhibiting distinct clinical behaviors;these sometimes co-exist as“hybrid”EpS[2,3].
