Traditional medicine,deeply rooted in cultural practices and historical wisdom,has faced surging challenges due to the escalating demand for plant-based remedies.This comprehensive review critically emphasizes the urg...Traditional medicine,deeply rooted in cultural practices and historical wisdom,has faced surging challenges due to the escalating demand for plant-based remedies.This comprehensive review critically emphasizes the urgent need for sustainable practices within traditional medicine,with a special focus on the potential of plant part substitution.Case studies that illuminate successful instances of substituting plant parts and providing a deep insight into viable alternatives to conventional practices are presented.Opportunities and challenges inherent in plant part substitution are discussed by addressing key considerations such as phytochemical and pharmacological aspects,safety and toxicity profiles,cultural insights,standardization,clinical validation,and regulatory compliance.This review serves as a guide for navigating the delicate balance between tradition and conservation within indigenous medicine practices.It underscores the importance of embracing sustainable approaches through plant part substitution,ensuring the preservation of cultural heritage while meeting the evolving healthcare needs of society.展开更多
The present study explored quality control of plant drug and polyherbal formulation using HPTLC and HPLC fingerprinting.The study combined qualitative analysis of Emodin and Rhein biomarker compound in Rhei Emodi Wall...The present study explored quality control of plant drug and polyherbal formulation using HPTLC and HPLC fingerprinting.The study combined qualitative analysis of Emodin and Rhein biomarker compound in Rhei Emodi Wall.rhizome extract and polyherbal formulation extract by HPTLC method with quantitative estimation of Emodin by HPLC method,aiming to help in accurate identification of Emodin and Rhein in plant materials,polyherbal formulations.This study also checked adulteration,with the purpose of improving bio-efficacy of ayurvedic formulation.All the samples showed characteristic peaks of Emodin at same retention time as that of standard Emodin.According to the HPTLC fingerprinting results,the Rf values of Rhein reference standard at 0.42 and Emodin at 0.62 were observed in test solution of Rhei emodi Wall.rhizome extract and polyherbal formulation extract and both were found comparable.The quantitative evaluation of Emodin present in the polyherbal formulation and Rhei emodi Wall.rhizome extracts were 0.0177% and 0.3106% respectively.展开更多
Shodhana(purification/detoxification)is an important aspect of Ayurveda.It has been described in several important pieces of literature.In this study,we performed shodhana process on Langali(Gloriosa superba Linn.)tub...Shodhana(purification/detoxification)is an important aspect of Ayurveda.It has been described in several important pieces of literature.In this study,we performed shodhana process on Langali(Gloriosa superba Linn.)tubers of family Liliaceae,a semi-woody herbaceous climber with significant therapeutic properties.We compared the unprocessed(before purification)and processed(after purification)samples based on the phytochemical,physicochemical,and chromatographic study,including HPTLC,HPLC,GC-MS and LC-MS.Significant changes were observed in profiling after the shodhana process.This plant contains colchicine,known for its toxic effects,particularly cardiotoxicity.Therefore,we quantified colchicine in the unprocessed and processed samples of Gloriosa superba Linn.tubers using HPLC method.Results showed that the percentage of colchicine was reduced by 13.67%in chloroform extract and 20.97%in ethanol extracts after the shodhana process.展开更多
文摘Traditional medicine,deeply rooted in cultural practices and historical wisdom,has faced surging challenges due to the escalating demand for plant-based remedies.This comprehensive review critically emphasizes the urgent need for sustainable practices within traditional medicine,with a special focus on the potential of plant part substitution.Case studies that illuminate successful instances of substituting plant parts and providing a deep insight into viable alternatives to conventional practices are presented.Opportunities and challenges inherent in plant part substitution are discussed by addressing key considerations such as phytochemical and pharmacological aspects,safety and toxicity profiles,cultural insights,standardization,clinical validation,and regulatory compliance.This review serves as a guide for navigating the delicate balance between tradition and conservation within indigenous medicine practices.It underscores the importance of embracing sustainable approaches through plant part substitution,ensuring the preservation of cultural heritage while meeting the evolving healthcare needs of society.
文摘The present study explored quality control of plant drug and polyherbal formulation using HPTLC and HPLC fingerprinting.The study combined qualitative analysis of Emodin and Rhein biomarker compound in Rhei Emodi Wall.rhizome extract and polyherbal formulation extract by HPTLC method with quantitative estimation of Emodin by HPLC method,aiming to help in accurate identification of Emodin and Rhein in plant materials,polyherbal formulations.This study also checked adulteration,with the purpose of improving bio-efficacy of ayurvedic formulation.All the samples showed characteristic peaks of Emodin at same retention time as that of standard Emodin.According to the HPTLC fingerprinting results,the Rf values of Rhein reference standard at 0.42 and Emodin at 0.62 were observed in test solution of Rhei emodi Wall.rhizome extract and polyherbal formulation extract and both were found comparable.The quantitative evaluation of Emodin present in the polyherbal formulation and Rhei emodi Wall.rhizome extracts were 0.0177% and 0.3106% respectively.
文摘Shodhana(purification/detoxification)is an important aspect of Ayurveda.It has been described in several important pieces of literature.In this study,we performed shodhana process on Langali(Gloriosa superba Linn.)tubers of family Liliaceae,a semi-woody herbaceous climber with significant therapeutic properties.We compared the unprocessed(before purification)and processed(after purification)samples based on the phytochemical,physicochemical,and chromatographic study,including HPTLC,HPLC,GC-MS and LC-MS.Significant changes were observed in profiling after the shodhana process.This plant contains colchicine,known for its toxic effects,particularly cardiotoxicity.Therefore,we quantified colchicine in the unprocessed and processed samples of Gloriosa superba Linn.tubers using HPLC method.Results showed that the percentage of colchicine was reduced by 13.67%in chloroform extract and 20.97%in ethanol extracts after the shodhana process.
