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Utility of trans-vaginal ultrasound in diagnosis and follow-up of non-pregnant sexually active females with lower ureteric calculi 被引量:1
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作者 Siddharth Pandey Tanica Pandey +5 位作者 Apul Goel ajay aggarwal Deepanshu Sharma Tushar Pandey Satya sankhwar Gaurav Garg 《Asian Journal of Urology》 CSCD 2020年第1期45-50,共6页
objective:To assess the utility of trans-vaginal ultrasonography in evaluation of non-pregnant sexually active female patients with lower ureteric calculi.Methods:A prospective study was done from January 2015 to Dece... objective:To assess the utility of trans-vaginal ultrasonography in evaluation of non-pregnant sexually active female patients with lower ureteric calculi.Methods:A prospective study was done from January 2015 to December 2017 including non-pregnant sexually active females with suspected ureteric calculus.Trans-abdominal ultrasound was initially done in all patients.In those patients in whom trans-abdominal ultrasound was inconclusive or there was indirect evidence of lower ureteric calculus in form of ureteral dila-tion but no calculus was evident,trans-vaginal ultrasound was done.The patients with ureteric calculi detected on trans-vaginal ultrasound and kept on conservative management were also followed up with trans-vaginal ultrasound.Non-contrast computed tomography was done in patients with inconclusive trans-vaginal ultrasound.Results:As per the study protocol,156 out of the total 468 patients evaluated by trans-abdominal ultrasound were eligible for trans-vaginal ultrasound.Trans-vaginal ultrasound was done in 149 patients,as seven patients did not give consent.Seventy-nine patients were detected with a lower ureteric calculus on trans-vaginal ultrasound and 27 patients had gyne-cologic or other cause for their symptoms.Forty-three patients had an inconclusive trans-vaginal ultrasound of which 36 underwent non-contrast computed tomography,among them only one patient had a lower ureteric calculus.Stone free status could be easily demonstrated on follow-up trans-vaginal ultrasound. 展开更多
关键词 Trans-abdominal ultrasound Trans-vaginal ultrasound Lower ureteric calculus Ureteric colic URETER
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欧洲药品管理局批准的抗肿瘤药物总生存和生活质量获益证据的可用性:2009-2013年获批药物的回顾性队列研究
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作者 Courtney Davis Huseyin Naci +5 位作者 Evrim Gurpinar Elita Poplavska Ashlyn Pinto ajay aggarwal 翟婧彤(译) 马飞(校) 《英国医学杂志中文版》 2018年第11期624-624,共1页
目的 确定欧洲批准的抗肿瘤药物总生存和生活质量获益数据的可用性。 设计 回顾性队列研究。 背景2009-2013年欧洲药品管理局(EMA)公开监管和科学报告的审批药物。 主要结局测量抗肿瘤药物上市后临床试验的设计特点(随机、交叉、盲法)... 目的 确定欧洲批准的抗肿瘤药物总生存和生活质量获益数据的可用性。 设计 回顾性队列研究。 背景2009-2013年欧洲药品管理局(EMA)公开监管和科学报告的审批药物。 主要结局测量抗肿瘤药物上市后临床试验的设计特点(随机、交叉、盲法)、参考标准以及研究终点,在审批时和上市后确定的总生存获益或生活质量改善程度和可用性。经验证的欧洲临床肿瘤协会临床获益量表(ESMO-MCBS)用于评估发表的抗肿瘤药物研究报告的生存获益的临床价值。 展开更多
关键词 抗肿瘤药物 药品管理局 生活质量 队列研究 可用性 欧洲 证据 临床试验
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