Aeropropulsion System Test Facility (ASTF) is required to accurately control the pressure and temperature of the airflow to test the performance of the aero-engine. However, the control accuracy of ASTF is significant...Aeropropulsion System Test Facility (ASTF) is required to accurately control the pressure and temperature of the airflow to test the performance of the aero-engine. However, the control accuracy of ASTF is significantly affected by the flow disturbance caused by aero-engine acceleration and deceleration. This would reduce the credibility of ASTF’s test results for the aero-engine. Therefore, first, this paper proposes a feedforward compensation-based L1 adaptive control method for ASTF to address this problem. The baseline controller is first designed based on ideal uncoupled closed-loop dynamics to achieve dynamic decoupling. Then, L1 adaptive control is adopted to deal with various uncertainties and ensure good control performance. To further enhance the anti-disturbance performance, a feedforward strategy based on disturbance prediction is designed in the L1 adaptive control framework to compensate for the unmatched flow disturbance, which cannot be measured directly. In addition, this strategy takes into account the effects of actuator dynamics. With this method, the feedforward term can be determined from the nominal model parameters despite uncertainties. Finally, to demonstrate the effectiveness of the proposed method, various comparative experiments are performed on a hardware-in-the-loop system of ASTF. The experimental results show that the proposed method possesses excellent tracking performance, anti-disturbance performance and robustness.展开更多
As the pivotal test equipment of aero-engines design,finalization,improvement,modification,etc.,the Altitude Ground Test Facilities(AGTF)plays an important role in the research and development of the aero-engines.With...As the pivotal test equipment of aero-engines design,finalization,improvement,modification,etc.,the Altitude Ground Test Facilities(AGTF)plays an important role in the research and development of the aero-engines.With the rapid development of advanced high-performance aeroengine,the increasing demand of high-altitude simulation test is driving AGTF to improve its test ability and level of automation and intelligence.The modeling method,simulation tool,and control technology are the key factors to support the improvement of the AGTF control system.The main purpose of this paper is to provide an overview of modeling methods,simulation tools,and control technologies in AGTF control system for future research.First,it reviews the evolution of AGTF in the world,from the early formative stage to integration stage.Then,the mathematical modeling method of AGTF for control application is overviewed.Furthermore,the simulation tools used in the AGTF control system are overviewed from numerical simulation to hardware-in-loop simulation and further to semi-physical simulation.Meanwhile,the control technologies used in the AGTF control system are summarized from single-variable control to multivariable integrated control,and from classical control theory to modern control theory.Finally,recommendations for future research are outlined.Therefore,this review article provides extensive literature information for the modeling,simulation,and control design of AGTF for control application.展开更多
Background:The high prevalence of parasitic diseases leads to millions of deaths and disabilities each year in developing countries.China has also been greatly affected by parasitic infections,including filariasis,lei...Background:The high prevalence of parasitic diseases leads to millions of deaths and disabilities each year in developing countries.China has also been greatly affected by parasitic infections,including filariasis,leishmaniasis,malaria,schistosomiasis,and soil-transmitted nematodosis.However,the situation in China improved dramatically after comprehensive parasitic disease control efforts were strengthened,leading to the elimination of filariasis in 2006 and to significant control over other diseases.However,imported parasitic disease cases are inevitable,and such cases have increasingly been reported as a result of enhanced globalization and international or regional cooperation.These imported diseases represent a major obstacle to the elimination of several parasitoses,such as malaria.Main text:This paper reviews imported cases of parasitic diseases in China's Mainland,particularly malaria and schistosomiasis,based on data reported separately by the Chinese annual reports and from other published papers.We summarize the new challenges that face parasitic disease control efforts in China's Mainland and perspectives regarding better control.We argue that both the provision of professional education and updated training for medical care personnel and the management and surveillance of people entering China are essential.We recommend that Chinese migrant workers should be considered a priority group for health education and that public awareness of imported diseases should be emphasized.Furthermore,we underscore the importance of investigating the distribution of introduced/potential vectors,parasite susceptibility,and improvements in diagnostic techniques and drug stocks.Conclusions:Imported cases have become the main challenge to the elimination of several parasitoses,such as malaria and schistosomiasis,in China's Mainland.China should act to meet these challenges,which are closely associated with national biological safety.展开更多
Background:Canthariasis is a disease of humans caused by the infestation of beetle larvae.It is the second important insectal disease after myiasis.Several species of beetles are reported to cause the disease in gastr...Background:Canthariasis is a disease of humans caused by the infestation of beetle larvae.It is the second important insectal disease after myiasis.Several species of beetles are reported to cause the disease in gastrointestinal tract,urogenital system,nasal sinuses,ears and faces of mammals.The cigarette beetle Lasioderma serricorne is a widespread and destructive pest that usually feeds on tobacco,tea,beans,cereal grains,and animal and plant specimen.While there was no previous evidence of human infestation by this worm,we report the first case of L.serricorne infestation in a baby girl in China.Case presentation:Here the case,an eight-month-old baby girl with irritable feeling,rubbing eyes,history of contact with mud and eating oranges twice during five days before attendance,and having“worms”in her stool was admitted to the First Affiliated Hospital of Sun Yat-sen University,Guangzhou,China.The clinical examination revealed that the pulse rate,blood pressure and temperature were regular,and the examination of the head,neck,and chest were unremarkable.The stool specimens containing“worms”were sent to the Department of Parasitology,Zhongshan School of Medicine,Sun Yat-sen University.The worms were recovered,studied morphologically using naked eyes and anatomical lens,PCR analyzed targeting cytochrome oxidase subunit 1(COX1)and 18S rRNA genes,examined by sequence analyses of the PCR products and finally classified by phylogenetic analysis to identify their species.Based on the findings,the worms were diagnosed as the larvae of L.serricorne.Conclusion:This report implies that the baby had an infestation with the larvae of L.serricorne in the gastrointestine.During contact with mud or eating oranges by the girl,worm eggs were swallowed into the stomach and resisted gastric acid digestion which eventually hatched into larvae and caused canthariasis.The 8 months girl had underdeveloped immune system which might facilitate the disease.This report implicates that L.serricorne can infest human accidentally and cause canthariasis that may lead to severe damage to infant and older patient upon involvement of important organs of the body.The patients once diagnosed having canthariasis should be treated in time.展开更多
基金supported by the“Shuimu Tsinghua Scholar”Project,China(No.2024SM223)the National Science and Technology Major Project,China(No.Y2022-V-0002-0028).
文摘Aeropropulsion System Test Facility (ASTF) is required to accurately control the pressure and temperature of the airflow to test the performance of the aero-engine. However, the control accuracy of ASTF is significantly affected by the flow disturbance caused by aero-engine acceleration and deceleration. This would reduce the credibility of ASTF’s test results for the aero-engine. Therefore, first, this paper proposes a feedforward compensation-based L1 adaptive control method for ASTF to address this problem. The baseline controller is first designed based on ideal uncoupled closed-loop dynamics to achieve dynamic decoupling. Then, L1 adaptive control is adopted to deal with various uncertainties and ensure good control performance. To further enhance the anti-disturbance performance, a feedforward strategy based on disturbance prediction is designed in the L1 adaptive control framework to compensate for the unmatched flow disturbance, which cannot be measured directly. In addition, this strategy takes into account the effects of actuator dynamics. With this method, the feedforward term can be determined from the nominal model parameters despite uncertainties. Finally, to demonstrate the effectiveness of the proposed method, various comparative experiments are performed on a hardware-in-the-loop system of ASTF. The experimental results show that the proposed method possesses excellent tracking performance, anti-disturbance performance and robustness.
基金This study was co-supported by the National Science and Technology Major Project,China(No.J2019-V-0010-0104)Zhejiang Provincial Natural Science Foundation of China(No.LQ23E060007).
文摘As the pivotal test equipment of aero-engines design,finalization,improvement,modification,etc.,the Altitude Ground Test Facilities(AGTF)plays an important role in the research and development of the aero-engines.With the rapid development of advanced high-performance aeroengine,the increasing demand of high-altitude simulation test is driving AGTF to improve its test ability and level of automation and intelligence.The modeling method,simulation tool,and control technology are the key factors to support the improvement of the AGTF control system.The main purpose of this paper is to provide an overview of modeling methods,simulation tools,and control technologies in AGTF control system for future research.First,it reviews the evolution of AGTF in the world,from the early formative stage to integration stage.Then,the mathematical modeling method of AGTF for control application is overviewed.Furthermore,the simulation tools used in the AGTF control system are overviewed from numerical simulation to hardware-in-loop simulation and further to semi-physical simulation.Meanwhile,the control technologies used in the AGTF control system are summarized from single-variable control to multivariable integrated control,and from classical control theory to modern control theory.Finally,recommendations for future research are outlined.Therefore,this review article provides extensive literature information for the modeling,simulation,and control design of AGTF for control application.
基金This work was supported by grants from the National Key R&D Program of China(No.2016YFC1200500)the National Natural Science Foundation of China(No.81601781)the China Postdoctoral Science Foundation(No.KLF201012).
文摘Background:The high prevalence of parasitic diseases leads to millions of deaths and disabilities each year in developing countries.China has also been greatly affected by parasitic infections,including filariasis,leishmaniasis,malaria,schistosomiasis,and soil-transmitted nematodosis.However,the situation in China improved dramatically after comprehensive parasitic disease control efforts were strengthened,leading to the elimination of filariasis in 2006 and to significant control over other diseases.However,imported parasitic disease cases are inevitable,and such cases have increasingly been reported as a result of enhanced globalization and international or regional cooperation.These imported diseases represent a major obstacle to the elimination of several parasitoses,such as malaria.Main text:This paper reviews imported cases of parasitic diseases in China's Mainland,particularly malaria and schistosomiasis,based on data reported separately by the Chinese annual reports and from other published papers.We summarize the new challenges that face parasitic disease control efforts in China's Mainland and perspectives regarding better control.We argue that both the provision of professional education and updated training for medical care personnel and the management and surveillance of people entering China are essential.We recommend that Chinese migrant workers should be considered a priority group for health education and that public awareness of imported diseases should be emphasized.Furthermore,we underscore the importance of investigating the distribution of introduced/potential vectors,parasite susceptibility,and improvements in diagnostic techniques and drug stocks.Conclusions:Imported cases have become the main challenge to the elimination of several parasitoses,such as malaria and schistosomiasis,in China's Mainland.China should act to meet these challenges,which are closely associated with national biological safety.
基金supported by the National High Technology Research and Development Program of China(2015AA020934)National Natural Science Foundation of China(30972574)+4 种基金National Natural Science Foundation of China(81201309)China Postdoctoral Science Foundation(2011 M501363)Natural Science Foundation of Guangdong Province of China(S2012040007256)Foundation of Doctoral Program of Higher Education of China(20120171120049)the design of the study,collection,analysis and interpretation of data,and writing the manuscript.
文摘Background:Canthariasis is a disease of humans caused by the infestation of beetle larvae.It is the second important insectal disease after myiasis.Several species of beetles are reported to cause the disease in gastrointestinal tract,urogenital system,nasal sinuses,ears and faces of mammals.The cigarette beetle Lasioderma serricorne is a widespread and destructive pest that usually feeds on tobacco,tea,beans,cereal grains,and animal and plant specimen.While there was no previous evidence of human infestation by this worm,we report the first case of L.serricorne infestation in a baby girl in China.Case presentation:Here the case,an eight-month-old baby girl with irritable feeling,rubbing eyes,history of contact with mud and eating oranges twice during five days before attendance,and having“worms”in her stool was admitted to the First Affiliated Hospital of Sun Yat-sen University,Guangzhou,China.The clinical examination revealed that the pulse rate,blood pressure and temperature were regular,and the examination of the head,neck,and chest were unremarkable.The stool specimens containing“worms”were sent to the Department of Parasitology,Zhongshan School of Medicine,Sun Yat-sen University.The worms were recovered,studied morphologically using naked eyes and anatomical lens,PCR analyzed targeting cytochrome oxidase subunit 1(COX1)and 18S rRNA genes,examined by sequence analyses of the PCR products and finally classified by phylogenetic analysis to identify their species.Based on the findings,the worms were diagnosed as the larvae of L.serricorne.Conclusion:This report implies that the baby had an infestation with the larvae of L.serricorne in the gastrointestine.During contact with mud or eating oranges by the girl,worm eggs were swallowed into the stomach and resisted gastric acid digestion which eventually hatched into larvae and caused canthariasis.The 8 months girl had underdeveloped immune system which might facilitate the disease.This report implicates that L.serricorne can infest human accidentally and cause canthariasis that may lead to severe damage to infant and older patient upon involvement of important organs of the body.The patients once diagnosed having canthariasis should be treated in time.
