Bacterial biofilms(BFs)are widely present in nature,and more than 99%of bacteria can form BF,which is an important factor leading to persistent infection of refractory wound and repeated infection.The formation of BF i...Bacterial biofilms(BFs)are widely present in nature,and more than 99%of bacteria can form BF,which is an important factor leading to persistent infection of refractory wound and repeated infection.The formation of BF is a dynamic cyclic process involving various physical,chemical and biological processes,mainly including bacterial attachment,BF formation and maturation,and bacterial diffusion.The bacteria in bacterial biofilms are more resistant to antibiotics and disinfectants,and more resilient to environmental changes,which presents many challenges in treatment.This article reviews the basic characteristics,resistance mechanisms and treatment strategies of BF.At present,there are many studies on the treatment of BF,which need to be selected according to the specific situation and pathophysiological process of wound infection,and can be used as a single method or in combination.This article introduces some treatment methods to provide a reference for the clinical prevention and treatment of BF.展开更多
Colon cancer is one of the top three malignant tumors in the world,in recent years,the incidence and mortality of this disease are increasing,which seriously threatens human life and health.At present,surgery is still...Colon cancer is one of the top three malignant tumors in the world,in recent years,the incidence and mortality of this disease are increasing,which seriously threatens human life and health.At present,surgery is still the main treatment for colon cancer,combined with chemotherapy and other measures can effectively improve the survival of patients.Different surgical methods have different prognostic effects on patients.In terms of intraoperative lymph node dissection for colon cancer,lymph node dissection during total mesocolic resection and D3 radical resection has significantly improved prognosis for colon cancer.Lymph node metastasis of colon cancer is common,with the presence of skip metastasis,lymph node dissection is important for the prognosis of patients,tumor recurrence and tumor metastasis.Therefore,it is necessary to make clear the diagnosis and lymph node metastasis before surgery,determine the surgical procedure and the scope of lymph node dissection,so as to avoid postoperative complications caused by inadequate tumor recurrence or excessive clearance.展开更多
文摘Bacterial biofilms(BFs)are widely present in nature,and more than 99%of bacteria can form BF,which is an important factor leading to persistent infection of refractory wound and repeated infection.The formation of BF is a dynamic cyclic process involving various physical,chemical and biological processes,mainly including bacterial attachment,BF formation and maturation,and bacterial diffusion.The bacteria in bacterial biofilms are more resistant to antibiotics and disinfectants,and more resilient to environmental changes,which presents many challenges in treatment.This article reviews the basic characteristics,resistance mechanisms and treatment strategies of BF.At present,there are many studies on the treatment of BF,which need to be selected according to the specific situation and pathophysiological process of wound infection,and can be used as a single method or in combination.This article introduces some treatment methods to provide a reference for the clinical prevention and treatment of BF.
文摘Colon cancer is one of the top three malignant tumors in the world,in recent years,the incidence and mortality of this disease are increasing,which seriously threatens human life and health.At present,surgery is still the main treatment for colon cancer,combined with chemotherapy and other measures can effectively improve the survival of patients.Different surgical methods have different prognostic effects on patients.In terms of intraoperative lymph node dissection for colon cancer,lymph node dissection during total mesocolic resection and D3 radical resection has significantly improved prognosis for colon cancer.Lymph node metastasis of colon cancer is common,with the presence of skip metastasis,lymph node dissection is important for the prognosis of patients,tumor recurrence and tumor metastasis.Therefore,it is necessary to make clear the diagnosis and lymph node metastasis before surgery,determine the surgical procedure and the scope of lymph node dissection,so as to avoid postoperative complications caused by inadequate tumor recurrence or excessive clearance.
