BACKGROUND Gallstones and gallbladder wall thickening(GBWT)are frequent findings in patients with cirrhosis,reflecting the critical interplay between hepatobiliary dysfunction and portal hypertension.AIM To assess the...BACKGROUND Gallstones and gallbladder wall thickening(GBWT)are frequent findings in patients with cirrhosis,reflecting the critical interplay between hepatobiliary dysfunction and portal hypertension.AIM To assess the prevalence of gallstones and asymptomatic GBWT in patients with cirrhosis.METHODS Hospitalized patients with cirrhosis who had undergone abdominal imaging studies during hospitalization were retrospectively analyzed.RESULTS A total of 128 patients were included.The patients had a mean age of 64±12.2 years,were predominantly male(73.4%),and most had decompensated liver cirrhosis(DeCi)(78.1%).Alcohol-associated liver disease(47.7%)and metabolic dysfunction-associated steatohepatitis(16.4%)are the leading causes of cirrhosis.Most patients were classified as Child-Pugh stage B(53.1%),followed by stage C(32%),and stage A(14.8%).A significant percentage of patients had cholelithiasis(39.8%),and DeCi patients were more likely to have gallstones(45%)than compensated patients(21.4%)(P=0.024).Furthermore,a significant number of patients had asymptomatic GBWT(32.8%),and almost half(42.9%)did not have concurrent cholelithiasis.Patients with DeCi were significantly more likely to have GBWT(39%)than those with compensated disease(10.7%)(P=0.005).There was no statistical correlation between cirrhosis etiology and cholelithiasis or Tsankof A et al.Gallstones and GBWT in patients with cirrhosis WJCC https://www.wjgnet.com 2 January 6,2026 Volume 14 Issue 1 GBWT.CONCLUSION This study underlines the high prevalence of radiologic gallbladder findings in patients with cirrhosis while simultaneously serving as a reminder to clinicians to refrain from accrediting these findings to a diagnosis of acute cholecystitis in the absence of symptoms.展开更多
Acute decompensation in cirrhotic patients signifies the onset of clinically evident events due to portal hypertension.The transition from compensated to decom-pensated cirrhosis involves hemodynamic changes leading t...Acute decompensation in cirrhotic patients signifies the onset of clinically evident events due to portal hypertension.The transition from compensated to decom-pensated cirrhosis involves hemodynamic changes leading to multiorgan dysfun-ction,managed predominantly in outpatient settings with regular monitoring.The mortality risk is elevated in decompensated patients.Therefore,diligent outpatient management should focus on regular medical follow-ups,medication adjustments,patient education,addressing emergent issues and evaluation for liver transplantation.The ultimate goal is to improve quality of life,prevent di-sease progression,reduce complications,and assess possible recompensation.This guide provides valuable recommendations for medical experts managing de-compensated cirrhotic patients post-hospitalization.展开更多
文摘BACKGROUND Gallstones and gallbladder wall thickening(GBWT)are frequent findings in patients with cirrhosis,reflecting the critical interplay between hepatobiliary dysfunction and portal hypertension.AIM To assess the prevalence of gallstones and asymptomatic GBWT in patients with cirrhosis.METHODS Hospitalized patients with cirrhosis who had undergone abdominal imaging studies during hospitalization were retrospectively analyzed.RESULTS A total of 128 patients were included.The patients had a mean age of 64±12.2 years,were predominantly male(73.4%),and most had decompensated liver cirrhosis(DeCi)(78.1%).Alcohol-associated liver disease(47.7%)and metabolic dysfunction-associated steatohepatitis(16.4%)are the leading causes of cirrhosis.Most patients were classified as Child-Pugh stage B(53.1%),followed by stage C(32%),and stage A(14.8%).A significant percentage of patients had cholelithiasis(39.8%),and DeCi patients were more likely to have gallstones(45%)than compensated patients(21.4%)(P=0.024).Furthermore,a significant number of patients had asymptomatic GBWT(32.8%),and almost half(42.9%)did not have concurrent cholelithiasis.Patients with DeCi were significantly more likely to have GBWT(39%)than those with compensated disease(10.7%)(P=0.005).There was no statistical correlation between cirrhosis etiology and cholelithiasis or Tsankof A et al.Gallstones and GBWT in patients with cirrhosis WJCC https://www.wjgnet.com 2 January 6,2026 Volume 14 Issue 1 GBWT.CONCLUSION This study underlines the high prevalence of radiologic gallbladder findings in patients with cirrhosis while simultaneously serving as a reminder to clinicians to refrain from accrediting these findings to a diagnosis of acute cholecystitis in the absence of symptoms.
文摘Acute decompensation in cirrhotic patients signifies the onset of clinically evident events due to portal hypertension.The transition from compensated to decom-pensated cirrhosis involves hemodynamic changes leading to multiorgan dysfun-ction,managed predominantly in outpatient settings with regular monitoring.The mortality risk is elevated in decompensated patients.Therefore,diligent outpatient management should focus on regular medical follow-ups,medication adjustments,patient education,addressing emergent issues and evaluation for liver transplantation.The ultimate goal is to improve quality of life,prevent di-sease progression,reduce complications,and assess possible recompensation.This guide provides valuable recommendations for medical experts managing de-compensated cirrhotic patients post-hospitalization.
