Objective:To identify the antibacterial potential of seagrass(Syringodium isoetifoliutn) associate microbes against bacterial pathogens.Methods:Eumeration of microbial associates were analyzed with leaf and root sampl...Objective:To identify the antibacterial potential of seagrass(Syringodium isoetifoliutn) associate microbes against bacterial pathogens.Methods:Eumeration of microbial associates were analyzed with leaf and root samples of Syringodium isoetifolium.MIC and MBC were calculated for bacterial pathogens with microbial associates.Phylogenetic and GC-MS analysis were calculated for Actinomycetes sp.(Act01) which was the most potent.Results:Of the isolated microbial associates phosphatase producing bacterial isolates were identified as maximum [(26l.78±35.09) CFU×10~4/g]counts in root sample.Of the selected microbial isolates Actinomycete sp(Act01) showed broad spectrum of antibacterial activity against antibiotic resistant and fish bacterial pathogens.Phylogenetic analysis of Act01 showed maximum identities(99%) with the Streptomyces sp.(GU5500072).The 16s rDNA secondary structure of Act01 showed the free energy values as -366.3 kkal/mol.The GC-MS analysis Act01 showed maximum retention value with 23.742 RT and the corresponding chemical class was identified as 1,4-dihydroxy-2-(3- hydroxybutyl)-9,10-anthraquinone 9,10-anthrac.Conclusions:In conclusion,Streptomyces sp. (GU045544.1) from Syringodium isoetifolium could be used as potential antibacterial agent.展开更多
One in six deaths worldwide is caused by cancer,making it a major global health concern.Despite their effectiveness,traditional treatment approaches such as radiation therapy,chemotherapy,and surgery frequently have n...One in six deaths worldwide is caused by cancer,making it a major global health concern.Despite their effectiveness,traditional treatment approaches such as radiation therapy,chemotherapy,and surgery frequently have negative side effects and high costs.New approaches,such as gene therapy,are promising but are hampered by high costs and accessibility problems.Nanoparticles(NPs)facilitate targeted drug delivery by leveraging passive targeting mechanisms,such as the enhanced permeability and retention(EPR)effect,and by actively targeting surfaces with ligands for site-specific binding through the functionalization of surfaces.This approach enhances therapeutic results while lowering off-target toxicities.Notably,chemotherapeutic medications,immunotherapeutic agents,and photothermal therapies can now be delivered more precisely to the affected site using NP-based systems.By boosting particularity,reducing side effects,and tackling drug resistance,nanomedicine has the potential to revolutionize cancer treatment and ultimately advance personalized oncological care.These advancements highlight the possibilities for field growth,and future development regulations are detailed.展开更多
Organic solid waste from municipal,agricultural,biomass,and industrial sources poses significant concerns because of its continuous production and diverse chemical and physical characteristics.Proper handling and conv...Organic solid waste from municipal,agricultural,biomass,and industrial sources poses significant concerns because of its continuous production and diverse chemical and physical characteristics.Proper handling and conversion strategies are required to address these issues.The chemical looping process connects organic solid waste to energy production.It is aimed at achieving sustainability through efficient and economically viable methods.This review highlights various sources of organic solid waste and their environmental impacts.It de-scribes chemical looping conversion processes such as combustion,gasification,reforming,and pyrolysis,applied to organic solid waste.In addition,it presents an extensive overview of the applications of the chemical looping process in CO_(2) capture and utilization and in bioenergy production.This review also delves into technoeconomic analyses and feasibility considerations across chemical looping processes and applications.Further-more,it discusses the challenges and prospects for promoting potential industrial applications and areas for further research on chemical looping processes.展开更多
基金the Indian Council of Medical Research(ICMR),New Delhi for financial assistance
文摘Objective:To identify the antibacterial potential of seagrass(Syringodium isoetifoliutn) associate microbes against bacterial pathogens.Methods:Eumeration of microbial associates were analyzed with leaf and root samples of Syringodium isoetifolium.MIC and MBC were calculated for bacterial pathogens with microbial associates.Phylogenetic and GC-MS analysis were calculated for Actinomycetes sp.(Act01) which was the most potent.Results:Of the isolated microbial associates phosphatase producing bacterial isolates were identified as maximum [(26l.78±35.09) CFU×10~4/g]counts in root sample.Of the selected microbial isolates Actinomycete sp(Act01) showed broad spectrum of antibacterial activity against antibiotic resistant and fish bacterial pathogens.Phylogenetic analysis of Act01 showed maximum identities(99%) with the Streptomyces sp.(GU5500072).The 16s rDNA secondary structure of Act01 showed the free energy values as -366.3 kkal/mol.The GC-MS analysis Act01 showed maximum retention value with 23.742 RT and the corresponding chemical class was identified as 1,4-dihydroxy-2-(3- hydroxybutyl)-9,10-anthraquinone 9,10-anthrac.Conclusions:In conclusion,Streptomyces sp. (GU045544.1) from Syringodium isoetifolium could be used as potential antibacterial agent.
文摘One in six deaths worldwide is caused by cancer,making it a major global health concern.Despite their effectiveness,traditional treatment approaches such as radiation therapy,chemotherapy,and surgery frequently have negative side effects and high costs.New approaches,such as gene therapy,are promising but are hampered by high costs and accessibility problems.Nanoparticles(NPs)facilitate targeted drug delivery by leveraging passive targeting mechanisms,such as the enhanced permeability and retention(EPR)effect,and by actively targeting surfaces with ligands for site-specific binding through the functionalization of surfaces.This approach enhances therapeutic results while lowering off-target toxicities.Notably,chemotherapeutic medications,immunotherapeutic agents,and photothermal therapies can now be delivered more precisely to the affected site using NP-based systems.By boosting particularity,reducing side effects,and tackling drug resistance,nanomedicine has the potential to revolutionize cancer treatment and ultimately advance personalized oncological care.These advancements highlight the possibilities for field growth,and future development regulations are detailed.
文摘Organic solid waste from municipal,agricultural,biomass,and industrial sources poses significant concerns because of its continuous production and diverse chemical and physical characteristics.Proper handling and conversion strategies are required to address these issues.The chemical looping process connects organic solid waste to energy production.It is aimed at achieving sustainability through efficient and economically viable methods.This review highlights various sources of organic solid waste and their environmental impacts.It de-scribes chemical looping conversion processes such as combustion,gasification,reforming,and pyrolysis,applied to organic solid waste.In addition,it presents an extensive overview of the applications of the chemical looping process in CO_(2) capture and utilization and in bioenergy production.This review also delves into technoeconomic analyses and feasibility considerations across chemical looping processes and applications.Further-more,it discusses the challenges and prospects for promoting potential industrial applications and areas for further research on chemical looping processes.
