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Advances in nanoparticle-mediated cancer therapeutics:Current research and future perspectives
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作者 V.C.Deivayanai P.Thamarai +7 位作者 S.Karishma A.Saravanan P.R.Yaashikaa a.s.vickram R.V.Hemavathy R Rohith Kumar S.Rishikesavan S.Shruthi 《Cancer Pathogenesis and Therapy》 2025年第4期293-308,共16页
One in six deaths worldwide is caused by cancer,making it a major global health concern.Despite their effectiveness,traditional treatment approaches such as radiation therapy,chemotherapy,and surgery frequently have n... One in six deaths worldwide is caused by cancer,making it a major global health concern.Despite their effectiveness,traditional treatment approaches such as radiation therapy,chemotherapy,and surgery frequently have negative side effects and high costs.New approaches,such as gene therapy,are promising but are hampered by high costs and accessibility problems.Nanoparticles(NPs)facilitate targeted drug delivery by leveraging passive targeting mechanisms,such as the enhanced permeability and retention(EPR)effect,and by actively targeting surfaces with ligands for site-specific binding through the functionalization of surfaces.This approach enhances therapeutic results while lowering off-target toxicities.Notably,chemotherapeutic medications,immunotherapeutic agents,and photothermal therapies can now be delivered more precisely to the affected site using NP-based systems.By boosting particularity,reducing side effects,and tackling drug resistance,nanomedicine has the potential to revolutionize cancer treatment and ultimately advance personalized oncological care.These advancements highlight the possibilities for field growth,and future development regulations are detailed. 展开更多
关键词 Cancer CHEMOTHERAPY Drug delivery NANOMEDICINE THERAPEUTICS TOXICITY
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Assessing the techno-economic and sustainable potential of chemical looping for bioenergy production from organic solid wastes
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作者 Kamalesh Raja Thamarai Packiyam +2 位作者 A.Saravanan P.R.Yaashikaa a.s.vickram 《Energy Storage and Saving》 2025年第1期14-26,共13页
Organic solid waste from municipal,agricultural,biomass,and industrial sources poses significant concerns because of its continuous production and diverse chemical and physical characteristics.Proper handling and conv... Organic solid waste from municipal,agricultural,biomass,and industrial sources poses significant concerns because of its continuous production and diverse chemical and physical characteristics.Proper handling and conversion strategies are required to address these issues.The chemical looping process connects organic solid waste to energy production.It is aimed at achieving sustainability through efficient and economically viable methods.This review highlights various sources of organic solid waste and their environmental impacts.It de-scribes chemical looping conversion processes such as combustion,gasification,reforming,and pyrolysis,applied to organic solid waste.In addition,it presents an extensive overview of the applications of the chemical looping process in CO_(2) capture and utilization and in bioenergy production.This review also delves into technoeconomic analyses and feasibility considerations across chemical looping processes and applications.Further-more,it discusses the challenges and prospects for promoting potential industrial applications and areas for further research on chemical looping processes. 展开更多
关键词 Organic solid waste Chemical looping process CO_(2)capture BIOENERGY TECHNO-ECONOMICS
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