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Essentials of Nursing Care in Randomized Controlled Trials of Nurse-Led Interventions in Somatic Care: A Systematic Review 被引量:1
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作者 Bengt Fridlund A.C.Jonsson +11 位作者 E.K.Andersson S-V.Bala G-B.Dahlman a.forsberg S.Glasdam A.Hommel A.Kristensson C.Lindberg B.Sivberg A.Sjostrom-Strand J.Wihlborg K.Samuelson 《Open Journal of Nursing》 2014年第3期181-197,共17页
Background: Nursing practice has to contribute to evidence pointing out why there is a need for more nurse-designed randomized control trials (RCTs) focusing on evidence-based practice (EBP). How far this EBP has prog... Background: Nursing practice has to contribute to evidence pointing out why there is a need for more nurse-designed randomized control trials (RCTs) focusing on evidence-based practice (EBP). How far this EBP has progressed in different health aspects is usually established by systematic reviews of RCTs. Nurse-led RCTs exist but no study has addressed the essentials of nursing care. Aim: The aim was therefore to determine the essentials of nurses’ interventions by means of nurse-led RCTs in somatic care focusing on the stated context, goals, content, strategies as well as the nurse’s role related to effectiveness. Methods: A systematic review was realized according to Cochrane review assumptions to identify, appraise and synthesize all empirical evidence meeting pre-specified eligibility criteria. The PRISMA statement guided the data extraction process (n = 55) from PubMed and CINAHL. Results: Of the RCTs in somatic care, 71% showed a positive effectiveness of nurse-led interventions, of which the nurse had a significant role with regard to being the main responsible in 67% of the studies. Also, 47% of the RCTs presented a theoretical standpoint related to the nurse-led interventions and most prominent were international evidence-based guidelines. Goals were found to have either a patient-centered or a professional-centered ambition. Strategies were based on patient-directed initiatives, nurse-patient-directed initiatives or nurse-directed initiatives, while contents were built upon either a patient-nurse interaction or a nursing management plan. Conclusions: This review underlines the necessity of a holistic view of a person, as nurse-led RCTs comprising a patient-centered ambition, patient-directed initiative and patient-nurse interaction plan showed beneficial nursing care effectiveness, particularly if theory-based. In a nurse-led RCT, a basic theoretical perspective is advantageous as well as to elucidate the role of the nurse in relation to the estimated effects. 展开更多
关键词 NURSE-LED Nursing Care Randomized Controlled Trial Somatic Care Systematic Review
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耶尔森氏菌yopE位区的基因分析:一种新的调节yopE表达的保守位点——yerA
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作者 a.forsberg 戴翔 《地方病译丛》 北大核心 1992年第6期9-11,共3页
耶尔森氏菌属的人类致病菌均携有毒力必需的相关质粒。Cornelis 等氏已于最近证实了小肠结肠炎杆菌的 irF(lcrF)基因是一种直接作用于 yopH 基因上的转录活化子。已构建了数株假结核杆菌 YPⅢ(pIBl)yopE和 yopH 的特异突变体并发现其对... 耶尔森氏菌属的人类致病菌均携有毒力必需的相关质粒。Cornelis 等氏已于最近证实了小肠结肠炎杆菌的 irF(lcrF)基因是一种直接作用于 yopH 基因上的转录活化子。已构建了数株假结核杆菌 YPⅢ(pIBl)yopE和 yopH 的特异突变体并发现其对小鼠模型无毒。进一步的研究表明 yopE 基因与对培养的 Hela 细胞的细胞毒作用有关,yopH基因与抗小鼠腹膜巨噬细胞的吞噬能力有关。Biot 和 Cornelis 二氏证实假结核菌 展开更多
关键词 耶尔辛杆菌 基因 基因表达
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