Cellulose acetates with low degree of substituent(DS) were homogeneously synthesized in an ionic liquid,1-allyl-3-methyl-imidazolium chloride(AmimC1).Under mild reaction conditions,cellulose monoacetates(CMA) with the...Cellulose acetates with low degree of substituent(DS) were homogeneously synthesized in an ionic liquid,1-allyl-3-methyl-imidazolium chloride(AmimC1).Under mild reaction conditions,cellulose monoacetates(CMA) with the DS in a range from 0.34 to 1.60 were obtained.NMR analysis shows that the distribution of acetyl moieties among the three OH groups of anhydroglucose unit is C6■C3>C2 for the synthesized CMA.The water solubility measurement shows that the CMA samples with the DS ranging from 0.65 to 1.06 are readily dissolved in water.The relationship between the structure and water solubility of CMA was briefly discussed.展开更多
Cellulose acetate butyrates(CAB) were homogeneously synthesized in an ionic liquid,1-allyl-3-methyl-imidazolium chloride(AmimC1).By a sequence of first adding butyric anhydride and then acetic anhydride in the cellulo...Cellulose acetate butyrates(CAB) were homogeneously synthesized in an ionic liquid,1-allyl-3-methyl-imidazolium chloride(AmimC1).By a sequence of first adding butyric anhydride and then acetic anhydride in the cellulose/AmimCl solutions,CAB products with the butyryl contents ranging from 33% to 47%(mass) were obtained.NMR analysis showed that among the three OH groups of the anhydroglucose unit(AGU) of the synthesized CAB,the distribution of the butyryl moieties showed a preference at the C6 position,while the partial degree of substitution of acetyl moieties at the C6 position showed the minimum values.Solubility measurement showed that CAB samples readily dissolved in the common organic solvents,such as methyl ethyl ketone,dichloromethane,and ethyl acetate.展开更多
目的：探讨急性缺血性脑卒中严重程度与血清Adropin、神经元特异性烯醇化酶（ NES）、胱抑素C （ CysC）和血清淀粉酶样蛋白A（ SAA）水平的相关性。方法182例急性缺血性脑卒中患者作为研究对象，患者入院后进行美国国立卫生院神经功能...目的：探讨急性缺血性脑卒中严重程度与血清Adropin、神经元特异性烯醇化酶（ NES）、胱抑素C （ CysC）和血清淀粉酶样蛋白A（ SAA）水平的相关性。方法182例急性缺血性脑卒中患者作为研究对象，患者入院后进行美国国立卫生院神经功能缺损评分（ NIHSS评分）进行病情严重程度评定，患者根据NIHSS评分分为3组，≤4分为轻度组（ n ＝68），5～15分为中度组（ n ＝63），≥16分为重度组（ n ＝51）。选取同期健康体检者35例作为对照组。检测受检者血清Adropin、NES、CysC和SAA水平，并探讨其相关性。结果缺血性脑卒中组Adropin、NES、CysC和SAA水平与对照组比较，差异有统计学意义（ P ＜0滗．01）。急性缺血性脑卒中患者中、重度组NIHSS评分、Adropin、NES、CysC和SAA水平与轻度组比较，差异有统计学意义（ P ＜0．01），重度组NIHSS评分、Adropin、NES、CysC和SAA水平与中度组比较，差异有统计学意义（ P ＜0．01）。 NES、CysC和SAA水平与NIHSS评分呈正相关（ r值分别为0．953、0．972、0．984， P ＜0．05），Adropin水平与NIHSS评分呈负相关（ r ＝－0．953， P ＜0．05）。结论血清Adropin、NES、CysC和SAA与急性缺血性脑卒中患者有明显相关性，可以作为预测患者病情严重程度的试验室检测指标。展开更多
文摘Cellulose acetates with low degree of substituent(DS) were homogeneously synthesized in an ionic liquid,1-allyl-3-methyl-imidazolium chloride(AmimC1).Under mild reaction conditions,cellulose monoacetates(CMA) with the DS in a range from 0.34 to 1.60 were obtained.NMR analysis shows that the distribution of acetyl moieties among the three OH groups of anhydroglucose unit is C6■C3>C2 for the synthesized CMA.The water solubility measurement shows that the CMA samples with the DS ranging from 0.65 to 1.06 are readily dissolved in water.The relationship between the structure and water solubility of CMA was briefly discussed.
文摘Cellulose acetate butyrates(CAB) were homogeneously synthesized in an ionic liquid,1-allyl-3-methyl-imidazolium chloride(AmimC1).By a sequence of first adding butyric anhydride and then acetic anhydride in the cellulose/AmimCl solutions,CAB products with the butyryl contents ranging from 33% to 47%(mass) were obtained.NMR analysis showed that among the three OH groups of the anhydroglucose unit(AGU) of the synthesized CAB,the distribution of the butyryl moieties showed a preference at the C6 position,while the partial degree of substitution of acetyl moieties at the C6 position showed the minimum values.Solubility measurement showed that CAB samples readily dissolved in the common organic solvents,such as methyl ethyl ketone,dichloromethane,and ethyl acetate.
文摘目的：探讨急性缺血性脑卒中严重程度与血清Adropin、神经元特异性烯醇化酶（ NES）、胱抑素C （ CysC）和血清淀粉酶样蛋白A（ SAA）水平的相关性。方法182例急性缺血性脑卒中患者作为研究对象，患者入院后进行美国国立卫生院神经功能缺损评分（ NIHSS评分）进行病情严重程度评定，患者根据NIHSS评分分为3组，≤4分为轻度组（ n ＝68），5～15分为中度组（ n ＝63），≥16分为重度组（ n ＝51）。选取同期健康体检者35例作为对照组。检测受检者血清Adropin、NES、CysC和SAA水平，并探讨其相关性。结果缺血性脑卒中组Adropin、NES、CysC和SAA水平与对照组比较，差异有统计学意义（ P ＜0滗．01）。急性缺血性脑卒中患者中、重度组NIHSS评分、Adropin、NES、CysC和SAA水平与轻度组比较，差异有统计学意义（ P ＜0．01），重度组NIHSS评分、Adropin、NES、CysC和SAA水平与中度组比较，差异有统计学意义（ P ＜0．01）。 NES、CysC和SAA水平与NIHSS评分呈正相关（ r值分别为0．953、0．972、0．984， P ＜0．05），Adropin水平与NIHSS评分呈负相关（ r ＝－0．953， P ＜0．05）。结论血清Adropin、NES、CysC和SAA与急性缺血性脑卒中患者有明显相关性，可以作为预测患者病情严重程度的试验室检测指标。
