摘要
目的分离、鉴定过山蕨 (ComptosorussibiricusRupr )乙醇提取物中总黄酮的化学组成。 方法采用反复硅胶柱色谱法、制备薄层色谱法等进行分离纯化 ,并通过理化常数测定和光谱分析鉴定了其化学结构。结果分离得到了 6个黄酮类化合物 ,即山萘酚 (kaempferol,Ⅰ ) ,山萘酚 7 O α L 鼠李糖苷 (kaempferol 7 O α L rhamnoside,Ⅱ ) ,山萘酚 3 O β D 吡喃葡萄糖苷 (kaempferol3 O β D glucopyranoside,Ⅲ ) ,山萘酚 7 O β D 吡喃葡萄糖苷 (kaempferol 7 O β D glucopyranoside,Ⅳ ) ,山萘酚 3 ,7 二 O β D 吡喃葡萄糖苷 (kaempferol 3 ,7 di O β D glucopyranoside,Ⅴ ) ,过山蕨素 (山萘酚 3 O β D 葡萄糖 7 O α L 鼠李糖苷 ,kaempferol 3 O β D glucopyranoside 7 O α L rhamnoside,Ⅵ )。结论化合物Ⅱ为首次从该植物中分离得到。
Objective To study the chemical constituents of the total flavonoids from the ethanol(ω=0.7)extract of the whole herb of Comptosorus sibiricus Rupr..Methods The compounds were isolated by chromatography on the silica gel column and identified on the basis of physico-chemical constants and spectral analysis.Result Six compounds were isolated as kaempferol(Ⅰ), kaempferol-7-O-α-L-rhamnoside(Ⅱ), kaempferol 3-O-β-D- glucopyranoside(Ⅲ),kaempferol 7-O-β-D-glucopyranoside(Ⅳ),kaempferol 3,7-di-O-β-D-glucopyranoside(Ⅴ),kaempferol-3-O-β-D- glucopyranoside -7-O-α-L-rhamnoside(Ⅵ)respectively.Conclusion Compound Ⅱ is obtained from this plant for the first time.
出处
《沈阳药科大学学报》
CAS
CSCD
2004年第2期105-108,共4页
Journal of Shenyang Pharmaceutical University
关键词
过山蕨
化学成分
山萘酚苷
Comptosorus sibiricus Rupr
chemical constituents
kaempferol-O- glycoside
