摘要
Three water-soluble β-alanine C 60 adducts with different addition numbers, C 60(NHCH 2CH 2COONa) nH n(n=1,5,9), were synthesized. The products were characterized by FTIR, 1H NMR and elemental analysis. The antioxidant activity of these C 60 adducts as the quencher for superoxide anion radical O -· 2 was evaluated by chemiluminescence in the system of pyrogallol-luminol. The results indicate that the three C 60 derivatives are all excellent quencher for superoxide anion radical O -· 2. The concentrations of 50% inhibition are 252, 140, 112 μmol/L respectively. This high efficiency should be attributed to many factors such as the numbers of remaining double bonds, donor effect of amino group and steric effect. However, the above results also suggest the effect of the adducted β-alanine groups is predominated in this system.
Three water-soluble β-alanine C 60 adducts with different addition numbers, C 60(NHCH 2CH 2COONa) nH n(n=1,5,9), were synthesized. The products were characterized by FTIR, 1H NMR and elemental analysis. The antioxidant activity of these C 60 adducts as the quencher for superoxide anion radical O -· 2 was evaluated by chemiluminescence in the system of pyrogallol-luminol. The results indicate that the three C 60 derivatives are all excellent quencher for superoxide anion radical O -· 2. The concentrations of 50% inhibition are 252, 140, 112 μmol/L respectively. This high efficiency should be attributed to many factors such as the numbers of remaining double bonds, donor effect of amino group and steric effect. However, the above results also suggest the effect of the adducted β-alanine groups is predominated in this system.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
2003年第7期1231-1233,共3页
Chemical Journal of Chinese Universities
基金
国家教育部博士点基金 (批准号 :970 335 10 )
国家自然科学基金 (批准号 :2 0 171039)资助
