摘要
目的 研究肥胖男童的内分泌激素及瘦素水平。 方法 选择单纯性肥胖和正常体重男童各 6 0例 ,年龄在 7～ 13岁。测定体质指数 ( BMI)、瘦素、胰岛素、皮质醇及性腺激素并进行分析。 结果 肥胖男童较正常男童瘦素、胰岛素、皮质醇和雌二醇增加 ,睾酮和黄体生成激素减少 ,差异有显著性 ( P<0 .0 0 1,P<0 .0 5 ) ;逐步 logistic回归分析 ,肥胖男童体质指数与瘦素、胰岛素、孕酮、催乳激素之间有负相关 ,与皮质醇、雌二醇之间有正相关。 结论 肥胖男童内分泌功能存在异常 ,体质指数越大瘦素、胰岛素 ,孕酮和催乳激素水平越低 。
Objective To study the relations between Leptin,endocrinal function and BMI in obesity boys. Methods Sixty obesity boys and sixty normal one at the age of 7～13 years were selected. They were measured body mass index(BMI),Leptin, insulin,corticoids,and sex steroids. Results The levels of leptin,insulin,corticoids and estradiol in obesity boys were higher than those in normal one.and were lower than those in normal boys. There were significant difference between two groups.The BMI of obesity boys was correlative.negtively with the levels of leptin,insulin,progesterone and prolactin,and was correlative positively with the levels of corticoids and estrovite. Conclusion Serum leptin levels may be a marker to evaluate the endocrinal function in obesity and high level of insulin,cortrcoids,sex steroids.
出处
《中国生育健康杂志》
2003年第1期19-20,共2页
Chinese Journal of Reproductive Health
关键词
男性儿童
肥胖
体质指数
瘦素
内分泌功能
Chidhood,male
Obesity
Body mass index
Leptin
Endcrinal function
