摘要
为观察乌梅丸合痛泻药方治疗溃疡性结肠炎的临床疗效及对NO的影响。选取治疗组和对照组各 30例 ,治疗组应用乌梅丸合痛泻药方内服加保留灌肠 ;对照组应用补脾益肠丸 ,两组疗程均为 30天。观察治疗前后大便次数和性状、腹痛、结肠镜、钡剂灌肠的变化 ,并采用硝酸还原法测定血清NO-3 浓度以反映一氧化氮 (NO)生成情况。结果 :治疗组临床治愈 12例 ,有效 10例 ,总有效率 73 3% ;对照组临床治愈 7例 ,有效 9例 ,总有效率 5 3 3%(P <0 0 5 )。两组治疗后 ,血中NO浓度均有所下降 ,但治疗组明显优于对照组 (P <0 0 1)。
To observe the clinical efficacy of combined 'Wu Mei Wan' and 'Tong Xie Yao Fang' in the treatment of ulcerative colitis (UC) and its influence on nitrous oxide (NO),30 cases in treatment group were treated by the oral administration and enema retention of combined formula,and another 30 cases in control group were treated by 'Bu Pi Yi Chang Pill',both with a course of 30 days.The defecation frequency,nature of stools,abdominal pain,colonoscopic results and barium enema conditions were observed;the content of serum NO through the assay of nitrate reductase was determined before and after treatment.Results:In treatment group,12 cases were clinically cured and 10 cases got effectiveness,and the total effective rate being 73 3%;in control group,7 cases were clinically cured and 9 cases got effectiveness,the total effective rate being 53 3%, P <0 05;the content of NO reduced more obviously in treatment group than in control group, P <0 01.
出处
《上海中医药杂志》
北大核心
2003年第1期35-36,共2页
Shanghai Journal of Traditional Chinese Medicine
