摘要
Rational design has become a key focus in artificial nanozyme research,driven by their cost-efficiency and high sensitivity.This work introduces a simplified sintering approach to synthesize MXene quantum dot@CoOx(MQDs@CoOx)composites,showcasing superior peroxidase-mimicking activity.Steady-state fluorescence analysis demonstrated that MQDs@CoOx efficiently decomposes H_(2)O_(2) into hydroxyl radicals(·OH).Density functional theory(DFT)simulations revealed that the Co-Ti dimer interfacial active site is responsible for the enhanced catalytic performance,significantly promoting H_(2)O_(2) activation and•OH generation.Utilizing this property,a highly sensitive colorimetric sensor for profenofos detection was developed,reaching a detection limit of 0.68 nM with a relative standard deviation(RSD)of 1.02%–2.65%.This study proposes an innovative strategy for designing peroxidase-mimicking enzymes using MQDs,demonstrating their promising applications in environmental pollutant detection and food safety monitoring.
基金
supported by the National Natural Science Foundation of China(42407324)
Natural Science Foundation of Gansu Province(21JR1RA247,25JRRA179)
Lanzhou Jiaotong university-Tianjin uni-versity joint innovation fund(LH2024001).
