摘要
Long-wavelength fluorescent dyes have revolutionized in vivo fluorescence imaging by offering unparalleled spatial resolution.Nevertheless,the majority of organic fluorescent dyes documented to date exhibit emission wavelengths predominantly within the range of 1000-1100 nm,with scarcely any surpassing the 1200 nm threshold.Herein,we introduce a heptamethine cyanine dye that boasts a remarkable fluorescence wavelength of 1239 nm.To our knowledge,this represents the longest fluorescence wavelength for heptamethine benzindole derivative.We have meticulously analyzed its photophysical characteristics and solvatochromic behavior,and assessed its efficacy in vivo fluorescence imaging applications.
基金
supported by the National Natural Science Foundation of China(No.22277069)
Fundamental Research Program of Shanxi Province(Nos.202303021222134,202303021224003)
Open Project Fund from Key Laboratory of Coal Environmental Pathogenicity and Prevention(Shanxi Medical University),Ministry of Education,China(No.MEKLCEPP/SXMU-202414)
Doctor Fund Project of Shanxi Province(No.SD2324)
Doctor Fund Project of Shanxi Medical University(No.XD2222)。
