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Single-cell transcriptomics unveils iron dysregulation in macrophages:Implicated genes in periodontitis pathogenesis identified via Mendelian randomization

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摘要 Periodontitis,a chronic inflammatory condition,is one of the leading causes of tooth loss globally,contributing significantly to the burden of oral diseases.Its pathogenesis involves a multifaceted interaction between microbial dysbiosis and host immune responses,where macrophages are pivotal in regulating inflammation and tissue remodeling.
机构地区 College of Stomatology
出处 《Genes & Diseases》 2026年第1期95-98,共4页 基因与疾病(英文)
基金 supported by grants from the Chongqing Young and Middle-aged Medical High-end Talent Studio(2022CQBSHTB3083) the Program for Youth Innovation in Future Medicine of Chongqing Medical University(No.W0055) the Chongqing Municipal Postdoctoral Science Foundation Project(CSTB2023NSCQ-BHX0033).

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