摘要
目的探讨灵珠七宝散穴位贴敷联合头部穴位按摩干预老年轻度认知功能障碍(MCI)的临床疗效。方法选取119例老年MCI患者,按照随机数字表法将所有患者分为试验组(59例)和对照组(60例);在整个干预过程中,试验组有3例脱落、对照组有1例脱落,试验组最终纳入56例,对照组最终纳入59例。对照组接受常规健康宣教与耳穴压豆治疗,试验组在对照组常规健康宣教和耳穴压豆基础上,额外接受头部穴位按摩联合灵珠七宝散穴位贴敷治疗。比较两组患者干预前后简易精神状态检查量表(MMSE)评分、匹兹堡睡眠质量指数(PSQI)评分、老年抑郁量表(GDS)评分、不良反应发生情况。结果干预后,两组患者MMSE评分较干预前提高,且试验组MMSE评分(24.87±1.73)分高于对照组的(23.97±1.02)分,差异显著(P<0.05)。干预后,两组患者PSQI评分较干预前降低,且试验组PSQI评分(6.39±2.21)分低于对照组的(9.53±3.09)分,差异显著(P<0.05)。干预后,两组患者GDS评分较干预前降低,且试验组GDS评分(8.16±3.39)分低于对照组的(12.23±4.75)分,差异显著(P<0.05)。两组不良反应发生率比较,无显著差异(P>0.05)。结论灵珠七宝散穴位贴敷联合头部穴位按摩能够改善老年MCI患者的认知功能、抑郁程度及睡眠质量,提高患者的生活质量。
Objective To explore the clinical efficacy of Lingzhu Qibao San acupoint application combined with head acupoint massage in elderly patients with mild cognitive impairment(MCI).Methods A total of 119 elderly patients with MCI were divided into an experimental group(59 cases)and a control group(60 cases)according to random numerical table.During the entire intervention process,3 cases dropped out from the experimental group and 1 case from the control group.The final number of participants in the experimental group was 56,and that in the control group was 59.The control group received routine health education and auricular acupressure.The experimental group additionally received head acupoint massage combined with Lingzhu Qibao San acupoint application on top of the routine health education and auricular acupressure of the control group.Comparison was made on mini-mental state examination(MMSE)score,pittsburgh sleep quality index(PSQI)score and geriatric depression scale(GDS)score before and after the intervention,and occurrence of adverse reactions between the two groups.Results After the intervention,MMSE scores in both groups were increased compared to before the intervention.Moreover,the MMSE scores in the experimental group was higher than the control group[(24.87±1.73)points vs.(23.97±1.02)points],and the difference was significant(P<0.05).After the intervention,the PSQI scores in both groups decreased compared to before the intervention.Moreover,the PSQI score of the experimental group was lower than the control group[(6.39±2.21)points vs.(9.53±3.09)points],and the difference was significant(P<0.05).After the intervention,the GDS scores in both groups decreased compared to before the intervention.Moreover,the GDS score in the experimental group was lower than the control group[(8.16±3.39)points vs.(12.23±4.75)points],and the difference was significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Lingzhu Qibao San acupoint application combined with head acupoint massage can effectively improve cognitive function,relieve depressive symptoms,and enhance sleep quality in elderly patients with MCI.
作者
杨涛
纪竹秋
魏永军
宫厚前
李翔宇
YANG Tao;JI Zhu-qiu;WEI Yong-jun(Qingdao West-Coast Economic New Area Lingzhushan Hospital,Qingdao 266515,China)
出处
《中国实用医药》
2026年第7期120-123,共4页
China Practical Medicine
关键词
灵珠七宝散
中药
穴位贴敷
穴位按摩
老年轻度认知障碍
Lingzhu Qibao San
Traditional Chinese medicine
Acupoint application
Head acupoint massage
Mild cognitive impairment in the elderly
