摘要
目的:探讨瑞马唑仑联合氢吗啡酮在老年腰椎椎间融合术患者中的麻醉效果及安全性。方法:选取2024年1月至12月于本院拟行腰椎椎间融合术的患者114例作为研究对象,随机分为对照组和观察组,每组各57例。对照组采用丙泊酚联合吗啡酮麻醉。观察组采用瑞马唑仑联合氢吗啡酮麻醉。分析比较两组的生命体征[术中血氧饱和度(Pulse Oximetry,SpO2)、心率(Heart Rate,HR)、平均动脉压(Mean Arterial Pressure,MAP)、呼吸频率(Respiratory Rate,RR)]、时间指标[手术时间、拔管时间、恢复室驻留时间、术后住院时间]、疼痛程度及并发症情况。结果:T1、T2、T3时,观察组的SpO2、HR、MAP、RR的变化幅度均明显小于对照组(P<0.05)。观察组的拔管时间、恢复室驻留时间均明显短于对照组(P<0.05)。但两组的手术时间、术后住院时间均无显著差异。术后4 h、术后8 h、术后12 h、术后24 h,两组的VAS评分均无显著差异。观察组的并发症发生率明显低于对照组。结论:瑞马唑仑联合氢吗啡酮应用在老年腰椎椎间融合术患者麻醉中,可有效维持术中生命体征的稳定,缩短患者恢复时间,提升安全性。
Objective:To explore the anesthetic effect and safety of remimazolam combined with hydromorphinone in elderly patients undergoing lumbar intervertebral fusion.Methods:114 patients who were scheduled to undergo lumbar intervertebral fusion in our hospital from January to December 2024 were selected as the research subjects.The patients were randomly divided into the control group and the observation group,with 57 cases in each group.The control group was anesthetized with propofol combined with hydromorphinone.The observation group was anesthetized with remimazolam combined with hydromorphinone.The vital signs[intraoperative Pulse Oximetry(SpO2),Heart Rate(HR),Mean Arterial Pressure(MAP),Respiratory Rate(RR)],time indicators[operation time,extubation time,recovery room stay time,postoperative hospital stay time],pain degree and complications of the two groups were analyzed and compared.Results:At T1,T2 and T3,the variation amplitudes of SpO2,HR,MAP and RR in the observation group were significantly smaller than those in the control group(P<0.05).The extubation time and the stay time in the recovery room of the observation group were significantly shorter than those of the control group(P<0.05).However,there were no significant differences in the operation time and postoperative hospital stay between the two groups At 4 hours,8 hours,12 hours and 24 hours after the operation,there were no significant differences in the VAS scores between the two groups.The incidence of complications in the observation group was significantly lower than that in the control group(P<0.05).Conclusion:The application of remimazolam combined with hydromorphine in the anesthesia of elderly patients undergoing lumbar intervertebral fusion can effectively maintain the stability of vital signs during the operation,shorten the recovery time of patients,and improve safety.
作者
蔡萌
Cai Meng(Anesthesiology Department,Tianjin Kanghui Hospital,Tianjin 300oo0,China)
关键词
瑞马唑仑
氢吗啡酮
腰椎椎间融合术
麻醉效果
Remimazolam
Hydromorphinone
Lumbar intervertebral fusion
Anesthetic effect
