摘要
目的以二维斑点追踪成像(2D-STI)观察脓毒症患儿左心室收缩功能变化。方法回顾性选择29例脓毒症患儿,根据相关诊断标准分为严重脓毒症组(n=10)与非严重脓毒症组(n=19),另以21名健康儿童为对照组;比较3组间及两两组间常规超声心动图参数及2D-STI参数。结果3组间左心房内径(LAD)、左心室舒张末期内径(LVEDD)及右心房内径(RAD)差异均有统计学意义(P均<0.05),而右心室舒张末期内径(RVEDD)及左心室射血分数(LVEF)差异均无统计学意义(P均>0.05)。3组间左心室整体纵向应变(LVGLS)及基底段前壁(BA)、基底段前侧壁(BAL)、基底段后侧壁(BIL)、中间段前壁(MA)、中间段前侧壁(MAL)、中间段后侧壁(MIL)、心尖段前壁(APA)、心尖段侧壁(APL)、心尖段下壁(API)、心尖帽(APEX)节段纵向应变(LS)差异均有统计学意义(P均<0.05);其中,两两组间比较LVGLS差异均有统计学意义(P均<0.05),严重脓毒症组与对照组BAL、BIL、MA、MAL、MIL、APA、APL、API及APEX节段LS,非严重脓毒症组与对照组BAL及MAL节段LS,严重脓毒症组与非严重脓毒症组BA、MA、APL、API及APEX节段LS差异均有统计学意义(P均<0.05)。结论脓毒症患儿LVEF尚在正常范围时左心室2D-STI参数已发生变化,且部分参数与病情严重程度有关。
Objective To observe the changes of left ventricular systolic function in children with sepsis by two-dimensional speckle tracking imaging(2D-STI).Methods A total of 29 children with sepsis were retrospectively enrolled and divided into severe sepsis group(n=10)and non-severe sepsis group(n=19)according to relevant diagnostic criteria,while 21 healthy children were taken as controls(control group).Conventional echocardiographic parameters and 2D-STI parameters were compared among 3 groups and between each 2 groups.Results Significant differences of left atrial diameter(LAD),left ventricular end-diastolic diameter(LVEDD)and right atrial diameter(RAD)were found among 3 groups(all P<0.05),while no significant difference of right ventricular end-diastolic diameter(RVEDD)nor left ventricular ejection fraction(LVEF)was noticed(both P>0.05).Meanwhile,significant differences of left ventricular global longitudinal strain(LVGLS)and basal anterior(BA),basal anterolateral(BAL),basal inferolateral(BIL),mid-anterior(MA),mid-anterolateral(MAL),mid-inferolateral(MIL),apical anterior(APA),apical lateral(APL),apical inferior(API)and apex cap(APEX)segment longitudinal strain(LS)were found among 3 groups(all P<0.05),also of LVGLS between each 2 groups,of LS in BAL,BIL,MA,MAL,MIL,APA,APL,API and APEX segments between severe sepsis group and control group,of LS in BAL and MAL segments between non-severe sepsis group and control group,and of LS in BA,MA,APL,API and APEX segments between severe sepsis group and non-severe sepsis group(all P<0.05).Conclusion Left ventricular 2D-STI parameters in children with sepsis changed when LVEF was still in normal range,and some parameters were related to the severity of disease.
作者
熊叶
周欢
彭晶
冯肖媛
XIONG Ye;ZHOU Huan;PENG Jing;FENG Xiaoyuan(Cardiac Ultrasound Room,Wuhan Children s Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430000,China)
出处
《中国医学影像技术》
北大核心
2025年第10期1667-1671,共5页
Chinese Journal of Medical Imaging Technology
