摘要
血府逐瘀汤为中医活血化瘀经典方剂,具调节炎症反应、细胞凋亡与增殖等功效。现代研究显示,其主要通过调控核转录因子-κB(NF-κB)信号通路中的相关因子,在心血管疾病、神经系统疾病、肿瘤及呼吸系统疾病等领域发挥防治作用。血府逐瘀汤临床应用广泛,但其防治疾病的药理作用及分子机制尚未完全明确,今后需对其活性成分、作用靶点及与其他信号通路的相互作用开展深入研究,以进一步明确其临床应用价值。
Xuefu Zhuyu Decoction is a classic traditional Chinese medicine formula for promoting blood circulation and removing blood stasis,with effects such as regulating inflammatory responses,cell apoptosis,and proliferation.Modern research shows that it mainly exerts preventive and therapeutic effects in cardiovascular diseases,neurological diseases,tumors,and respiratory diseases by regulating related factors in the nuclear transcription factor kappa-B(NF-kB)signaling pathway.Xuefu Zhuyu Decoction has a wide range of clinical applications,but its pharmacological effects and molecular mechanisms in disease prevention and treatment have not yet been fully eucidated.In the future,in-depth research should be conducted on its active components,action targets,and interactions with other signaling pathways to further clarify its clinical application value.
作者
李容杭
陈越
宋春燕
郑爽
Li Ronghang;Chen Yue;Song Chunyan;Zheng Shuang(The Second Hospital of Jilin University,Changchun 130041,China;Jilin Provincial Cancer Hospital,Changchun 130012,China)
出处
《长春中医药大学学报》
2025年第11期1280-1285,共6页
Journal of Changchun University of Chinese Medicine
基金
吉林省科技发展计划项目(YDZJ202501ZYTS674)。
关键词
血府逐瘀汤
NF-ΚB信号通路
活血化瘀
Xuefu Zhuyu Decoction
nuclear transcription factor kappa-B signaling pathway
promoting blood circulation and removing blood stasis
